Zobrazeno 1 - 7 of 7 pro vyhledávání: '"Joshua M. Britt"'
1
Rapid, effective, and long-lasting behavioral recovery produced by microsutures, methylene blue, and polyethylene glycol after completely cutting rat sciatic nerves
Autor: Aleksej Zuzek, Wesley P. Thayer, George D. Bittner, Francisco Gonzalez-Lima, Timothy J Schallert, Cameron P. Keating, Joshua M. Britt, Christopher S. Spaeth, Jacqueline R. Kane, R. W. Wilcott, J. D. Fan, Jonathan M. Winograd
Publikováno v: Journal of Neuroscience Research. 90:967-980
Behavioral function lost in mammals (including humans) after peripheral nerve severance is slowly (weeks to years) and often poorly restored by 1-2-mm/day, nonspecifically directed outgrowths from proximal axonal stumps. To survive, proximal stumps m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cba8e64b4d1dcf23b650556b5dd5883d
https://doi.org/10.1002/jnr.23023
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2
Assessing the role of dopamine in limb and cranial-oromotor control in a rat model of Parkinson's disease
Autor: Joshua M. Britt, Nathan Tews, Lawrence K. Cormack, Jacqueline R. Kane, Timothy J Schallert, Sean T. Ma, Michelle R. Ciucci, Allison M. Ahrens, John A. Russell, Amber Jacobs
Publikováno v: Journal of Communication Disorders. 44:529-537
Parkinson's disease (PD) is a neurodegenerative disorder primarily characterized by sensorimotor dysfunction. The neuropathology of PD includes a loss of dopamine (DA) neurons of the nigrostriatal pathway. Classic signs of the disease include rigidit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3f4ea880b681c5b109195e4eecd5210
https://doi.org/10.1016/j.jcomdis.2011.04.005
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3
Polyethylene Glycol Rapidly Restores Axonal Integrity and Improves the Rate of Motor Behavior Recovery After Sciatic Nerve Crush Injury
Autor: Melengor Y. Gbanaglo, Joshua M. Britt, Aleksej Zuzek, George D. Bittner, Jacqueline R. Kane, Cody J. Estler, Garrett L. Robinson, Christopher S. Spaeth, Elaine A. Boydston, Timothy J Schallert
Publikováno v: Journal of Neurophysiology. 104:695-703
The inability to rapidly (within minutes to hours) improve behavioral function after severance of peripheral nervous system axons is an ongoing clinical problem. We have previously reported that polyethylene glycol (PEG) can rapidly restore axonal in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24c190456661e1ba8f320f2053fd953b
https://doi.org/10.1152/jn.01051.2009
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4
Cooling enhances in vitro survival and fusion-repair of severed axons taken from the peripheral and central nervous systems of rats
Autor: George D. Bittner, Timothy C. Marzullo, Ronda C. Stavisky, Joshua M. Britt
Publikováno v: Neuroscience Letters. 327:9-12
Severed segments of rat peripheral (PNS; sciatic) and central nervous system (CNS; spinal) axons continue to conduct action potentials when maintained in vitro at 6-9 degrees C for up to 7 (sciatic axons) and 2 days (spinal axons), compared with only
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24a77cf2e72390517d0f817dce7160b1
https://doi.org/10.1016/s0304-3940(02)00378-6
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5
Melatonin enhances the in vitro and in vivo repair of severed rat sciatic axons
Autor: Aleksej Zuzek, George D. Bittner, Joshua M. Britt, Elizabeth Truong, Ronda C. Stavisky
Publikováno v: Neuroscience letters. 376(2)
This study examines the effects of several experimental compounds [melatonin (MEL), cyclosporin A (CsA), glial-derived neurotrophic factor (GDNF), and methylprednisolone (MP)] on polyethylene glycol (PEG)-induced repair in vitro and/or in vivo by pla
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abefc80e680fecdcf74fa4001b5dcca9
https://pubmed.ncbi.nlm.nih.gov/15698928
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6
Degeneration of mammalian PNS and CNS axons is accelerated by incubation with protein synthesis inhibitors
Autor: Ronda C. Stavisky, Tuan Pham, Joshua M. Britt, Timothy C. Marzullo, George D. Bittner, Aleksej Zuzek
Publikováno v: Neuroscience research. 47(4)
Protein synthesis inhibitors (PSIs) increase the rate of degeneration, as measured by compound action potential (CAP) conduction, in segments of rat PNS and CNS axons. Sciatic axonal segments maintained in vitro in Krebs at 37-38 degrees C generate C
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac5d80b717e62b80f15ab8c2947d75c3
https://pubmed.ncbi.nlm.nih.gov/14630349
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