Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Joshua M Mitchell"'
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 6, p e1011912 (2024)
To standardize metabolomics data analysis and facilitate future computational developments, it is essential to have a set of well-defined templates for common data structures. Here we describe a collection of data structures involved in metabolomics
Externí odkaz:
https://doaj.org/article/9e39222fa6d9460a9f0042e59533afb4
Publikováno v:
Frontiers in Genetics, Vol 5 (2014)
Large-scale identification of metabolites is key to elucidating and modeling metabolism at the systems level. Advances in metabolomics technologies, particularly ultra-high resolution mass spectrometry enable comprehensive and rapid analysis of metab
Externí odkaz:
https://doaj.org/article/629b8d6baf8946f08e8f37d6af3802f4
Publikováno v:
Metabolites, Vol 12, Iss 6, p 515 (2022)
We present a novel, scan-centric method for characterizing peaks from direct injection multi-scan Fourier transform mass spectra of complex samples that utilizes frequency values derived directly from the spacing of raw m/z points in spectral scans.
Externí odkaz:
https://doaj.org/article/42860590aa964706ad90e15f4fbdbc7a
Publikováno v:
Metabolites, Vol 11, Iss 11, p 740 (2021)
Lung cancer remains the leading cause of cancer death worldwide and non-small cell lung carcinoma (NSCLC) represents 85% of newly diagnosed lung cancers. In this study, we utilized our untargeted assignment tool Small Molecule Isotope Resolved Formul
Externí odkaz:
https://doaj.org/article/71d7cd8c2dff47edba9bb2a5e5e4c12f
Autor:
Russell M. Grandbois, Peter H. Santschi, Chen Xu, Joshua M. Mitchell, Daniel I. Kaplan, Chris M. Yeager
Publikováno v:
Frontiers in Chemistry. 11
129I is a nuclear fission decay product of concern because of its long half-life (16 Ma) and propensity to bioaccumulate. Microorganisms impact iodine mobility in soil systems by promoting iodination (covalent binding) of soil organic matter through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9589ba2408e5a22f46c520624f2643b
https://doi.org/10.3389/fchem.2023.1105641
https://doi.org/10.3389/fchem.2023.1105641
Autor:
Joshua M. Mitchell, Justin W. Mabin, Laura K. Muehlbauer, Douglas S. Annis, Sameer K. Mathur, Mats W. Johansson, Alex S. Hebert, Frances J. Fogerty, Joshua J. Coon, Deane F. Mosher
IL5 and IL33 are major activating cytokines that cause circulating eosinophils to polarize, adhere, and release their granule contents. We correlated microscopic features of purified human blood eosinophils stimulated for 10 min with IL5 or IL33 with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b26f3f5c6e09636afba41f549701f691
https://doi.org/10.1101/2022.12.21.521419
https://doi.org/10.1101/2022.12.21.521419
Autor:
Joshua M. Mitchell, Cynthia M. June, Vincent L. Baggett, Beth C. Lowe, James F. Ruble, Robert A. Bonomo, David A. Leonard, Rachel A. Powers
Publikováno v:
Journal of Biological Chemistry. 298:102127
The evolution of multidrug resistance in Acinetobacter spp. increases the risk of our best antibiotics losing their efficacy. From a clinical perspective, the carbapenem-hydrolyzing class D β-lactamase subfamily present in Acinetobacter spp. is part
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb51e2aa50b9d6b8a286dc648efba57
https://doi.org/10.1016/j.jbc.2022.102127
https://doi.org/10.1016/j.jbc.2022.102127
Lung cancer is the leading cause of cancer death worldwide and non-small cell lung carcinoma (NSCLC) represents 85% of newly diagnosed lung cancers. The high mortality rate of lung cancer is due in part to the lack of effective treatment options for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a29a6a85ddb7774dff665618c80d367
https://doi.org/10.1101/2021.03.16.21253733
https://doi.org/10.1101/2021.03.16.21253733
Autor:
Josephine P. Werner, Joshua M. Mitchell, Magdalena A. Taracila, Robert A. Bonomo, Rachel A. Powers
Publikováno v:
Protein Science. 26:515-526
β-lactam antibiotics are crucial to the management of bacterial infections in the medical community. Due to overuse and misuse, clinically significant bacteria are now resistant to many commercially available antibiotics. The most widespread resista
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c19e906dca45edf50a02a2d9af8607fe
https://doi.org/10.1002/pro.3100
https://doi.org/10.1002/pro.3100
Publikováno v:
Analytical chemistry. 91(14)
Improvements in Fourier transform mass spectrometry (FT-MS) enable increasingly more complex experiments in the field of metabolomics. What is directly detected in FT-MS spectra are spectral features (peaks) that correspond to sets of adducted and ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab45adb172d5ecefab6f72310546691e
https://pubmed.ncbi.nlm.nih.gov/31260262
https://pubmed.ncbi.nlm.nih.gov/31260262