Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Joshua M, Bock"'
Autor:
Joshua M. Bock, PhD, Keith A. Needham, BS, David A. Gregory, MPA, Mercedes M. Ekono, MPH, Emerson M. Wickwire, PhD, Virend K. Somers, MD, PhD, Amir Lerman, MD
Publikováno v:
Mayo Clinic Proceedings: Innovations, Quality & Outcomes, Vol 6, Iss 2, Pp 166-175 (2022)
Objective: To determine whether continuous positive airway pressure (CPAP) adherence reduces health care–related costs or use in patients with obstructive sleep apnea (OSA) and comorbid cardiovascular disease (CVD). Patients: A total of 23 million
Externí odkaz:
https://doaj.org/article/31771d162f6a480fb5c07943adfc2ea5
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13094 (2023)
Patients with obstructive sleep apnea (OSA) have a heightened risk of developing cardiovascular diseases, namely hypertension. While seminal evidence indicates a causal role for sympathetic nerve activity in the hypertensive phenotype commonly observ
Externí odkaz:
https://doaj.org/article/745b607be44d4a2e8c038e16c55ef49d
Autor:
Joshua M. Bock, Kirk J. Rodysill, Andrew D. Calvin, Soumya Vungarala, Karine R. Sahakyan, Stephen S. Cha, Anna Svatikova, Francisco Lopez-Jimenez, Virend K. Somers
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Background: Ambulatory overnight oximetry (OXI) has emerged as a cost-effective initial test for sleep disordered breathing. Obesity is closely associated with obstructive sleep apnea (OSA); however, whether body mass index (BMI) or waist-to-hip rati
Externí odkaz:
https://doaj.org/article/a39791f2a5ef4f85bdbe50ade7cca53a
Autor:
Kristen D. Turner, Ana Kronemberger, Dam Bae, Joshua M. Bock, William E. Hughes, Kenichi Ueda, Andrew J. Feider, Satoshi Hanada, Luis G. O. de Sousa, Matthew P. Harris, Ethan J. Anderson, Sue C. Bodine, M. Bridget Zimmerman, Darren P. Casey, Vitor A. Lira
Publikováno v:
Nutrients, Vol 14, Iss 21, p 4479 (2022)
Nitric oxide (NO) stimulates mitochondrial biogenesis in skeletal muscle. However, NO metabolism is disrupted in individuals with type 2 diabetes mellitus (T2DM) potentially contributing to their decreased cardiorespiratory fitness (i.e., VO2max) and
Externí odkaz:
https://doaj.org/article/f0c4a9ef66794e1fb98cdb528fdffe87
Autor:
Joshua M. Bock, William E. Hughes, Kenichi Ueda, Andrew J. Feider, Satoshi Hanada, Darren P. Casey
Publikováno v:
Physiological Reports, Vol 9, Iss 5, Pp n/a-n/a (2021)
Abstract Microvascular endothelial dysfunction precipitates cardiovascular disease mortality in patients with type 2 diabetes mellitus (T2DM). However, the relationship between glycemic management and microvascular endothelial function of these patie
Externí odkaz:
https://doaj.org/article/f0e6e48dd2f14c91be99827c73b09415
Autor:
Joshua M. Bock, Brady E. Hanson, Kayla A. Miller, Nathanael T. Seaberg, Kenichi Ueda, Andrew J. Feider, Satoshi Hanada, Vitor A. Lira, Darren P. Casey
Publikováno v:
Journal of Applied Physiology. 133:1407-1414
We report that increasing nitric oxide bioavailability via 8 wk of inorganic nitrate/nitrite supplementation improves maximal aerobic exercise capacity in patients with type 2 diabetes mellitus. Similarly, we observed a rightward shift in the gas exc
Publikováno v:
Nutr Metab Cardiovasc Dis
BACKGROUND & AIMS: Peripheral artery disease (PAD) is characterized by elevated blood pressure (BP), low nitric oxide availability (NO), and exaggerated pressor responses to sympatho-excitatory stressors. Inorganic nitrate reduces peripheral BP in he
Publikováno v:
Nitric Oxide. 118:17-25
AIMS Patients with type 2 diabetes mellitus (T2DM) have reduced vasodilatory responses during exercise partially attributable to low nitric oxide (NO) levels. Low NO contributes to greater α-adrenergic mediated vasoconstriction in contracting skelet
Autor:
Kimberly A. Clevenger, Kelly A. Mackintosh, Melitta A. McNarry, Karin A. Pfeiffer, M. Benjamin Nelson, Joshua M. Bock, Mary T. Imboden, Leonard A. Kaminsky, Alexander H.K. Montoye
Publikováno v:
Journal of sports sciences.
Identifying the best analytical approach for capturing moderate-to-vigorous physical activity (MVPA) using accelerometry is complex but inconsistent approaches employed in research and surveillance limits comparability. We illustrate the use of a con
Publikováno v:
Am J Hypertens
While the contribution of several physiological systems to arterial blood pressure regulation has been studied extensively, the role of normal and disrupted sleep as a modifiable determinant of blood pressure control, and in the pathophysiology of hy