Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Joshua Lowitz"'
Autor:
Stephanie Maciuba, Gregory D. Bowden, Harrison J. Stratton, Kazimierz Wisniewski, Claudio D. Schteingart, Juan C. Almagro, Philippe Valadon, Joshua Lowitz, Scott M. Glaser, Grace Lee, Mahdi Dolatyari, Edita Navratilova, Frank Porreca, Pierre J.M. Rivière
Publikováno v:
mAbs, Vol 15, Iss 1 (2023)
ABSTRACTProlactin (PRL) has recently been demonstrated to elicit female-selective nociceptor sensitization and increase pain-like behaviors in female animals. Here we report the discovery and characterization of first-in-class, humanized PRL neutrali
Externí odkaz:
https://doaj.org/article/13a501dc4b6048c599396d77471221c9
Autor:
Kalyaneswar Mandal, Jarrett Adams, Dong Jun Lee, John Kenney, Dana Ault-Riche, Les P. Miranda, Sachdev S. Sidhu, Hongyan Li, Joshua Lowitz, Stephen B. H. Kent, Maruti Uppalapati
Publikováno v:
ACS chemical biology. 11(4)
Polypeptides composed entirely of d-amino acids and the achiral amino acid glycine (d-proteins) inherently have in vivo properties that are proposed to be near-optimal for a large molecule therapeutic agent. Specifically, d-proteins are resistant to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3a7ab6182823de66dab29904c3b7945
https://pubmed.ncbi.nlm.nih.gov/26745345
https://pubmed.ncbi.nlm.nih.gov/26745345
Autor:
Joshua Lowitz, Stephen B. H. Kent, John Kenney, Maruti Uppalapati, Dana Ault-Riche, Sachdev S. Sidhu, Kalyaneswar Mandal
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 109(37)
Total chemical synthesis was used to prepare the mirror image ( D -protein) form of the angiogenic protein vascular endothelial growth factor (VEGF-A). Phage display against D -VEGF-A was used to screen designed libraries based on a unique small prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e30f53e51152ddbe336632e7183ba5b
https://pubmed.ncbi.nlm.nih.gov/22927390
https://pubmed.ncbi.nlm.nih.gov/22927390