Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Joshua Letson"'
Autor:
Sudipta Baroi, Piotr J. Czernik, Mohd Parvez Khan, Joshua Letson, Emily Crowe, Amit Chougule, Patrick R. Griffin, Clifford J. Rosen, Beata Lecka-Czernik
Publikováno v:
Molecular Metabolism, Vol 88, Iss , Pp 102000- (2024)
Objective: The skeleton is one of the largest organs in the body, wherein metabolism is integrated with systemic energy metabolism. However, the bioenergetic programming of osteocytes, the most abundant bone cells coordinating bone metabolism, is not
Externí odkaz:
https://doaj.org/article/fd12f41dade74bab8b4e130e40b8ee7d
Publikováno v:
Bio-Protocol, Vol 9, Iss 19 (2019)
Co-culture systems utilizing reconstituted or synthetic extracellular matrix (ECM) and micropatterning techniques have enabled the reconstruction of surface epithelial tissues. This technique has been utilized in the regeneration, disease modeling an
Externí odkaz:
https://doaj.org/article/fab23504023643348e93ed0d5b53c927
Autor:
Vandana Sharma, Veani Fernando, Joshua Letson, Yashna Walia, Xunzhen Zheng, Daniel Fackelman, Saori Furuta
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 4600 (2021)
S-nitrosylation is a selective and reversible post-translational modification of protein thiols by nitric oxide (NO), which is a bioactive signaling molecule, to exert a variety of effects. These effects include the modulation of protein conformation
Externí odkaz:
https://doaj.org/article/fcb7af49504c426284f4386362018744
Publikováno v:
Antioxidants, Vol 8, Iss 9, p 404 (2019)
Nitric oxide (NO) is a highly reactive molecule, generated through metabolism of L-arginine by NO synthase (NOS). Abnormal NO levels in mammalian cells are associated with multiple human diseases, including cancer. Recent studies have uncovered that
Externí odkaz:
https://doaj.org/article/d51f54e6e7f84a46bcab013fa3abdc55
Publikováno v:
Sci Signal
Cumulative evidence shows that fibrogenic stroma and stiff extracellular matrix (ECM) not only result from tumor growth but also play pivotal roles in cellular transformation and tumor initiation. This emerging concept may largely account for the inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4332987ba2bb1dfefd36ecfa13d7ae28
https://doi.org/10.1126/scisignal.abg3449
https://doi.org/10.1126/scisignal.abg3449
Autor:
Vandana Sharma, Joshua Letson, Andrea L. Nestor-Kalinoski, Saori Furuta, Xunzhen Zheng, Gang Ren
Publikováno v:
Cancers
Volume 13
Issue 11
Cancers, Vol 13, Iss 2815, p 2815 (2021)
Volume 13
Issue 11
Cancers, Vol 13, Iss 2815, p 2815 (2021)
Simple Summary Fibrosis, which is often caused by chronic diseases and environmental substances, is closely associated with cancer. Thus, the development of a robust method allowing for deep studies of the linkage between fibrosis and cancer is essen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25e351039d6a0702f628314c04022b6a
http://europepmc.org/articles/PMC8201212
http://europepmc.org/articles/PMC8201212
Autor:
Allen Schroering, Saori Furuta, Gang Ren, Matthew Bommarito, Christopher Figy, Yashna Walia, Samantha Metzger, Xunzhen Zheng, Andrea Kalinoski, David A. Weaver, Joshua Letson, Kam C. Yeung
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-21 (2019)
Scientific Reports
Scientific Reports
One third of newly diagnosed breast cancers in the US are early-stage lesions. The etiological understanding and treatment of these lesions have become major clinical challenges. Because breast cancer risk factors are often linked to aberrant nitric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04a85c27ea5b1e6d22892ebc79b815bc
http://link.springer.com/article/10.1038/s41598-019-43239-x
http://link.springer.com/article/10.1038/s41598-019-43239-x
Autor:
Yashna Walia, Vandana Sharma, Daniel Fackelman, Xunzhen Zheng, Veani Fernando, Saori Furuta, Joshua Letson
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 4600, p 4600 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 4600, p 4600 (2021)
S-nitrosylation is a selective and reversible post-translational modification of protein thiols by nitric oxide (NO), which is a bioactive signaling molecule, to exert a variety of effects. These effects include the modulation of protein conformation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d46c6476b68fcf19413038345e6a0a7
https://pubmed.ncbi.nlm.nih.gov/33925645
https://pubmed.ncbi.nlm.nih.gov/33925645
Autor:
Xunzhen, Zheng, Veani, Fernando, Vandana, Sharma, Yashna, Walia, Joshua, Letson, Saori, Furuta
Publikováno v:
Biochemical pharmacology
Immunotherapy is a first-line treatment for many tumor types. However, most breast tumors are immunosuppressive and only modestly respond to immunotherapy. We hypothesized that correcting arginine metabolism might improve the immunogenicity of breast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4f8616277400c9943fd41c2844a9bf9d
https://pubmed.ncbi.nlm.nih.gov/32112882
https://pubmed.ncbi.nlm.nih.gov/32112882
Publikováno v:
Bio Protoc
Co-culture systems utilizing reconstituted or synthetic extracellular matrix (ECM) and micropatterning techniques have enabled the reconstruction of surface epithelial tissues. This technique has been utilized in the regeneration, disease modeling an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::961c4c6e4a95c5c3961c1e46c6ff9aa8
https://europepmc.org/articles/PMC7854015/
https://europepmc.org/articles/PMC7854015/
