Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Joshua L. Milstein"'
Autor:
Lisa A. Post, Joshua A. Kulas, Joshua L. Milstein, Sarah V. L. Sebastian, Seyyedmohsen Hosseini-Barkooie, Max E. Stevenson, George S. Bloom, Heather A. Ferris
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract While historically viewed as an insulin insensitive organ, it is now accepted that insulin has a role in brain physiology. Changes in brain insulin and IGF1 signaling have been associated with neurological diseases, however the molecular fac
Externí odkaz:
https://doaj.org/article/f1aaef2f449c46ba99d160a3b2b7f049
Autor:
Joshua L. Milstein, Heather A. Ferris
Publikováno v:
Molecular Metabolism, Vol 52, Iss , Pp 101234- (2021)
Background: The brain was once thought of as an insulin-insensitive organ. We now know that the insulin receptor is present throughout the brain and serves important functions in whole-body metabolism and brain function. Brain insulin signaling is in
Externí odkaz:
https://doaj.org/article/8a883d3d22e14261938274aff05a741e
Publikováno v:
Frontiers in Neurology, Vol 10 (2019)
Objective: To test the hypothesis that Multiple Sclerosis (MS) patients have increased peripheral inflammation compared to healthy donors and that this systemic activation of the immune system, reflected by acute phase reactants (APRs) measured in th
Externí odkaz:
https://doaj.org/article/3a5a97cdaf874f48b384e6cbfd8006a7
Publikováno v:
Mult Scler Relat Disord
ObjectiveMultiple sclerosis is a chronic neuroinflammatory disorder, in which activated immune cells directly or indirectly induce demyelination and axonal degradation. Inflammatory stimuli also change the phenotype of astrocytes, making them neuroto
Publikováno v:
Frontiers in Neurology
Frontiers in Neurology, Vol 10 (2019)
Frontiers in Neurology, Vol 10 (2019)
Objective: To test the hypothesis that Multiple Sclerosis (MS) patients have increased peripheral inflammation compared to healthy donors and that this systemic activation of the immune system, reflected by acute phase reactants (APRs) measured in th
Autor:
Joshua L. Milstein, Antonia Santoro, Perri Hooper, Lillian Skeiky, Jeff Kukucka, Savanah Clark, Kimberly Cates, Julie Blandford
Publikováno v:
Eye on Psi Chi Magazine. 21:16-19
Autor:
Brian M. Polster, Jonathan W. VanRyzin, Shealinna X. Ge, Sausan M. Jaber, Joshua L. Milstein, Jaylyn Waddell
Publikováno v:
J Neurosci
Idebenone is a synthetic quinone that on reduction in cells can bypass mitochondrial Complex I defects by donating electrons to Complex III. The drug is used clinically to treat the Complex I disease Leber's hereditary optic neuropathy (LHON), but ha
Autor:
Post, Lisa A.1,2 (AUTHOR), Kulas, Joshua A.1,3 (AUTHOR), Milstein, Joshua L.1 (AUTHOR), Sebastian, Sarah V. L.3 (AUTHOR), Hosseini-Barkooie, Seyyedmohsen3 (AUTHOR), Stevenson, Max E.3 (AUTHOR), Bloom, George S.1,4 (AUTHOR), Ferris, Heather A.1,3 (AUTHOR) hf4f@virginia.edu
Publikováno v:
Scientific Reports. 7/18/2023, Vol. 13 Issue 1, p1-15. 15p.
Publikováno v:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association; 2023 Supplement, Vol. 19, p1-87, 87p
Autor:
Jaber, Sausan M., Ge, Shealinna X., Milstein, Joshua L., VanRyzin, Jonathan W., Waddell, Jaylyn, Polster, Brian M.
Publikováno v:
Journal of Neuroscience; 6/3/2020, Vol. 40 Issue 23, p4609-4619, 11p