Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Joshua L Schwartz"'
Autor:
Shivani Shukla, Joshua L. Schwartz, Callum Walsh, Wen Mai Wong, Vrund Patel, Yu-Peng Hsieh, Chichi Onwuasoanya, Shaoming Chen, Andreas Offenhäusser, Gert Cauwenberghs, Francesca Santoro, Alysson R. Muotri, Gene W. Yeo, Sreekanth H. Chalasani, Zeinab Jahed
Publikováno v:
Microsystems & Nanoengineering, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract The brain integrates activity across networks of interconnected neurons to generate behavioral outputs. Several physiological and imaging-based approaches have been previously used to monitor responses of individual neurons. While these tech
Externí odkaz:
https://doaj.org/article/b8bc8123d45b4d64a93b9b91cebbb8d5
Autor:
Megha eSubramanian, Christina K Timmerman, Joshua L Schwartz, Daniel L Pham, Mollie K. Meffert
Publikováno v:
Frontiers in Neuroscience, Vol 9 (2015)
The genetic and phenotypic heterogeneity of autism spectrum disorders (ASD) presents a substantial challenge for diagnosis, classification, research, and treatment. Investigations into the underlying molecular etiology of ASD have often yielded mixed
Externí odkaz:
https://doaj.org/article/eb1e763a45ed406f8d25d1194b8d5eac
Autor:
Kathryn H. Morelli, Wenhao Jin, Shashank Shathe, Assael A. Madrigal, Krysten L. Jones, Joshua L. Schwartz, Tristan Bridges, Jasmine R. Mueller, Archana Shankar, Isaac A. Chaim, John W. Day, Gene W. Yeo
Publikováno v:
Sci Transl Med
Myotonic dystrophy type 1 (DM1) is a multisystem, autosomal-dominant inherited disorder caused by CTG microsatellite repeat expansions (MREs) in the 3′ untranslated region of the dystrophia myotonica-protein kinase ( DMPK ) gene. Despite its promin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb6fa1febd240558019bfb8e656619b8
https://europepmc.org/articles/PMC9645119/
https://europepmc.org/articles/PMC9645119/
Publikováno v:
Critical reviews in biochemistry and molecular biology
Dozens of incurable neurological disorders result from expansion of short repeat sequences in both coding and non-coding regions of the transcriptome. Short repeat expansions underlie microsatellite repeat expansion (MRE) disorders including myotonic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94bfe32413e39aeae891212a3c5f1c94
http://europepmc.org/articles/PMC8192115
http://europepmc.org/articles/PMC8192115
Autor:
Hana Cho, Elizabeth T. Abshire, Maximilian W. Popp, Christoph Pröschel, Joshua L. Schwartz, Gene W. Yeo, Lynne E. Maquat
Publikováno v:
Molecular cell. 82(15)
Despite a long appreciation for the role of nonsense-mediated mRNA decay (NMD) in destroying faulty, disease-causing mRNAs and maintaining normal, physiologic mRNA abundance, additional effectors that regulate NMD activity in mammalian cells continue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09393521d31c3541addbb2efae62a8ff
https://pubmed.ncbi.nlm.nih.gov/35675814
https://pubmed.ncbi.nlm.nih.gov/35675814
Autor:
Sebastian Markmiller, Joshua L. Schwartz, David E. Hill, Gene W. Yeo, Archana Shankar, Jonathan C. Schmok, Gabriel A. Pratt, Duy B. Scaletta, Brian A. Yee, Stefan Aigner, Frederick E. Tan, Shashank Sathe, Jason L. Nathanson, Yuanchi Ha, En-Ching Luo
Publikováno v:
Nature structural & molecular biology, vol 27, iss 10
Nat Struct Mol Biol
Nat Struct Mol Biol
The molecular functions of the majority of RNA-binding proteins (RBPs) remain unclear, highlighting a major bottleneck to a full understanding of gene expression regulation. Here, we develop a plasmid resource of 690 human RBPs that we subject to luc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6c24a6237dec4ffeb782ed4b0b5f261
https://escholarship.org/uc/item/5kd0v4kq
https://escholarship.org/uc/item/5kd0v4kq