Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Joshua L Everson"'
Autor:
Galen W Heyne, Cal G Melberg, Padydeh Doroodchi, Kia F Parins, Henry W Kietzman, Joshua L Everson, Lydia J Ansen-Wilson, Robert J Lipinski
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120517 (2015)
The Hedgehog (Hh) signaling pathway mediates multiple spatiotemporally-specific aspects of brain and face development. Genetic and chemical disruptions of the pathway are known to result in an array of structural malformations, including holoprosence
Externí odkaz:
https://doaj.org/article/0d35fea9865541e895abcebe1dd8023e
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89448 (2014)
Disruption of the Hedgehog signaling pathway has been implicated as an important molecular mechanism in the pathogenesis of fetal alcohol syndrome. In severe cases, the abnormalities of the face and brain that result from prenatal ethanol exposure fa
Externí odkaz:
https://doaj.org/article/ff9afc57459e433593597f62db921006
Autor:
Robert J Lipinski, Hunter T Holloway, Shonagh K O'Leary-Moore, Jacob J Ament, Stephen J Pecevich, Gary P Cofer, Francois Budin, Joshua L Everson, G Allan Johnson, Kathleen K Sulik
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102603 (2014)
Subtle behavioral and cognitive deficits have been documented in patient cohorts with orofacial clefts (OFCs). Recent neuroimaging studies argue that these traits are associated with structural brain abnormalities but have been limited to adolescent
Externí odkaz:
https://doaj.org/article/a44a4af0733e44ef83077693ea2498fc
Autor:
Robert J Lipinski, Peter Hammond, Shonagh K O'Leary-Moore, Jacob J Ament, Stephen J Pecevich, Yi Jiang, Francois Budin, Scott E Parnell, Michael Suttie, Elizabeth A Godin, Joshua L Everson, Deborah B Dehart, Ipek Oguz, Hunter T Holloway, Martin A Styner, G Allan Johnson, Kathleen K Sulik
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43067 (2012)
Prenatal ethanol exposure is the leading preventable cause of congenital mental disability. Whereas a diagnosis of fetal alcohol syndrome (FAS) requires identification of a specific pattern of craniofacial dysmorphology, most individuals with behavio
Externí odkaz:
https://doaj.org/article/f002b2c989d34d4bb0b782c406b0b246
Autor:
Matthew T. McLaughlin, Miranda R. Sun, Tyler G. Beames, Austin C. Steward, Joshua W. M. Theisen, Hannah M. Chung, Joshua L. Everson, Ivan P. Moskowitz, Michael D. Sheets, Robert J. Lipinski
Publikováno v:
Developmental Dynamics. 252:483-494
Frem1 has been linked to human face shape variation, dysmorphology, and malformation, but little is known about its regulation and biological role in facial development.During midfacial morphogenesis in mice, we observed Frem1 expression in the embry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af9f221212df12422809ee1e27ec2746
https://doi.org/10.1002/dvdy.555
https://doi.org/10.1002/dvdy.555
Autor:
Joshua L. Everson, Johann K. Eberhart
Publikováno v:
Current Topics in Developmental Biology ISBN: 9780128201572
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4371fea4720065cbae815aef93ed0b2d
https://doi.org/10.1016/bs.ctdb.2022.10.003
https://doi.org/10.1016/bs.ctdb.2022.10.003
Publikováno v:
Birth defects researchREFERENCES.
Losses and malformations of cranial neural crest cell (cNCC) derivatives are a hallmark of several common brain and face malformations. Nevertheless, the etiology of these cNCC defects remains unknown for many cases, suggesting a complex basis involv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84842ea11277b273921fcae51b30fdfb
https://pubmed.ncbi.nlm.nih.gov/36369674
https://pubmed.ncbi.nlm.nih.gov/36369674
Autor:
Matthew T. McLaughlin, Miranda R. Sun, Tyler G. Beames, Austin C. Steward, Joshua W. M. Theisen, Hannah M. Chung, Joshua L. Everson, Ivan P. Moskowitz, Michael D. Sheets, Robert J. Lipinski
The Frem/Fras family of extracellular matrix proteins has been linked to human face shape variation and malformation, but little is known about their regulation and biological roles in facial development. During midfacial morphogenesis in mice, we ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f5adb2ba963ac5b5be74e69a26aaace
https://doi.org/10.1101/2022.07.16.500318
https://doi.org/10.1101/2022.07.16.500318
Autor:
Beth A. Kozel, Paul Kruszka, Maximilian Muenke, Zoë C. Wong, Robert J. Lipinski, Kristen Malecki, Joshua L. Everson, Angela Troia, Yonit A. Addissie
Publikováno v:
Birth Defects Res
BACKGROUND: Holoprosencephaly is the most common malformation of the forebrain (1 in 250 embryos) with severe consequences for fetal and child development. This study evaluates nongenetic factors associated with holoprosencephaly risk, severity, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2218d5fb72bffd8fd3f91a3ff9fb379c
https://doi.org/10.1002/bdr2.1834
https://doi.org/10.1002/bdr2.1834
Autor:
Seth I. Berger, Maximilian Muenke, Omkar Hajirnis, Paul Kruszka, David R. Murdock, Raymond J. Louie, Joshua L. Everson, Luis F. Escobar, Chitra Prasad, Maria Iascone, Hülya Kayserili, Raymond A. Poot, Valentina Casa, Nancy J. Clegg, Evelien Zonneveld-Huijssoon, Anna Cereda, Jenna Gaesser, Meena Balasubramanian, Nicole Corsten-Janssen, Mike R. Dekker, Jacob Hogue, Mark J. Stephan, Mauricio R. Delgado, Ariel F. Martinez, Oebele F. Brouwer, Allison Schreiber, Ping Hu, Angie W Lichty, Vickie Zurcher, Kerstin S. Wendt, Karin Weiss, Eloise J. Prijoles, Robert J. Lipinski, Momoko Tanima-Nagai, Matthew A. Deardorff
Publikováno v:
Brain
Paediatrics Publications
Brain, 142, 2631-2643. Oxford University Press
Paediatrics Publications
Brain, 142, 2631-2643. Oxford University Press
Marked by incomplete division of the embryonic forebrain, holoprosencephaly is one of the most common human developmental disorders. Despite decades of phenotype-driven research, 80-90% of aneuploidy-negative holoprosencephaly individuals with a prob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fed82bfc0052080687c621419beb9552
https://pure.eur.nl/en/publications/51e947b8-750f-4483-9714-66e18a1776c5
https://pure.eur.nl/en/publications/51e947b8-750f-4483-9714-66e18a1776c5