Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Joshua Kellner"'
Autor:
Glenn E Winnier, Nick Valenzuela, Jennifer Peters-Hall, Joshua Kellner, Christopher Alt, Eckhard U Alt
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0221457 (2019)
Freshly isolated, uncultured, autologous adipose derived regenerative cells (ADRCs) have emerged as a promising tool for regenerative cell therapy. The Transpose RT system (InGeneron, Inc., Houston, TX, USA) is a system for isolating ADRCs from adipo
Externí odkaz:
https://doaj.org/article/da84c0753b414cfa805ad7577b67e935
Autor:
Simrit Parmar, Jaap Jan Boelens, Joseph D. Khoury, Yago Nieto, Stefan O. Ciurea, Uday R. Popat, Richard E. Champlin, Eric Yvon, Eveline M. Delemarre, Peter F. Thall, Hongbing Ma, Sairah Ahmed, Stefan Nierkens, Jennifer D Ramos, Joshua Kellner, Borje S. Andersson, Amanda Olson, Robert S. Negrin, Zeng Ke, Mitsutaka Nishimoto, Ian K. McNiece
Publikováno v:
Scopus-Elsevier
Oncotarget
Oncotarget
Incubation of umbilical cord blood (UCB) derived regulatory T-cells (Tregs) with fucosyltransferase enzyme improves their ability to home to the target tissue to prevent graft vs. host disease (GVHD). We report results of 5 patients (Double UCB Trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cb9ed9d949fbbcf1763667e1f877e84
https://doi.org/10.18632/oncotarget.26242
https://doi.org/10.18632/oncotarget.26242
Publikováno v:
Oncotarget. 9:33694-33701
Regulatory T cells (Tregs) are an important component of the immune system involved in regulation of immune cell proliferation and inflammatory responses and preventing autoimmune diseases. The use of Tregs in cellular therapy has recently been explo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55cd84f6eb21c4ee7f25c233d1660c56
https://doi.org/10.18632/oncotarget.26097
https://doi.org/10.18632/oncotarget.26097
Publikováno v:
JCI Insight. 4
Multiple myeloma (MM) is an incurable plasma cell malignancy with frequent treatment failures and relapses, suggesting the existence of pathogenic myeloma stem/progenitor populations. However, the identity of MM stem cells remains elusive. We used a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56bd080a57cf8724aece70849557c730
https://doi.org/10.1172/jci.insight.124698
https://doi.org/10.1172/jci.insight.124698
Autor:
Yuliya-Yael Miropolski, Joshua Kellner, Ayokunle A Ogunye, S. Daniliuc, Ian K. McNiece, D. Fiorentini, M. Genser-Nir
Publikováno v:
Future Science OA
Aim: Endothelial cells (ECs), isolated from peripheral blood (PB), bone marrow (BM) and cord blood (CB), are limited in numbers and expansion has had limited success. We used a novel serum-free medium (EndoGo) to evaluate effects on ex vivo expansion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7c8270eee1b45bdb8c06b4fd8eacabf
http://europepmc.org/articles/PMC6554691
http://europepmc.org/articles/PMC6554691
Publikováno v:
Leukemia Research. 40:54-59
Leukemic cell lines have become important tools for studies of disease providing a monoclonal cell population that can be extensively expanded in vitro while preserving leukemic cellular characteristics. However, studies of chronic lymphocytic leukem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13da10cfe8dc6def4e996ec5a8eb92a0
https://doi.org/10.1016/j.leukres.2015.10.008
https://doi.org/10.1016/j.leukres.2015.10.008
Autor:
Christopher Alt, Glenn E. Winnier, Jennifer Peters-Hall, Eckhard Alt, Joshua Kellner, Nick Valenzuela
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 9, p e0221457 (2019)
PLoS ONE, Vol 14, Iss 9, p e0221457 (2019)
Background: Freshly isolated, unmodified autologous adipose derived regenerative cells (ADRCs) (also named Stromal Vascular Fraction; SVF) have emerged as a promising tool for regenerative cell therapy. Due to regulatory concerns recently the use of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77f43b7357057c96c85377c1a78e9444
Publikováno v:
Cytotherapy. 17:1514-1523
Background aims Mesenchymal stromal cells (MSCs), derived from several tissues including bone marrow and adipose tissue, are being evaluated in clinical trials for a range of diseases. Virtually all tissues of the body contain stromal cells, yet it i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd1caf2a8ddc46efc88abd9184c8fae9
https://doi.org/10.1016/j.jcyt.2015.07.009
https://doi.org/10.1016/j.jcyt.2015.07.009
Autor:
Saad Z. Usmani, Zihai Li, Saleh Rachidi, Ronald A. DePinho, Joshua Kellner, Bei Liu, Shai White-Gilbertson, Gabriela Chiosis, Yunpeng Hua
Publikováno v:
Clinical Cancer Research. 19:6242-6251
Purpose: gp96 (grp94) is a key downstream chaperone in the endoplasmic reticulum (ER) to mediate unfolded protein response (UPR) and the pathogenesis of multiple myeloma is closely linked to dysregulated UPR. In this study, we aimed to determine the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1958800ac231b8b9e32ddf2993bdeb86
https://doi.org/10.1158/1078-0432.ccr-13-2083
https://doi.org/10.1158/1078-0432.ccr-13-2083
Publikováno v:
Natural Killer Cells ISBN: 9781493936823
As part of the innate immune system, natural killer (NK) cells are regarded as promising effector cells for adoptive cell therapy approaches to treat patients with cancer. In some cases, genetic modification of the NK cells may be considered but such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc09c8dfb8a685b8721a666bd7d7ab21
https://doi.org/10.1007/978-1-4939-3684-7_17
https://doi.org/10.1007/978-1-4939-3684-7_17