Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Joshua J. Sebranek"'
Autor:
Katrina J. Carter, Jaqueline K. Limberg, Rebecca E. Johansson, John W Harrell, Joshua J. Sebranek, Garrett L. Peltonen, Benjamin J. Walker, Marlowe W. Eldridge, William G. Schrage, J. Mikhail Kellawan
Publikováno v:
Am J Physiol Heart Circ Physiol
Central adiposity is associated with greater sympathetic support of blood pressure. β-adrenergic receptors (β-AR) buffer sympathetically mediated vasoconstriction and β-AR-mediated vasodilation is attenuated in preclinical models of obesity. With
Publikováno v:
DeckerMed Critical Care of the Surgical Patient.
Patients with diabetes mellitus routinely require management in the adult intensive care unit (ICU). These patients have increased morbidity, mortality, hospital length of stay, cost of care, and frequency of hospital and ICU admission. Glucose contr
Autor:
Joshua J. Sebranek, Jacqueline K. Limberg, Marlowe W. Eldridge, William G. Schrage, J. Mikhail Kellawan, Garrett L. Peltonen, Rebecca E. Johansson, John W. Harrell
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 310:H756-H764
We tested the hypothesis that women exhibit greater vasodilator responses to β-adrenoceptor stimulation compared with men. We further hypothesized women exhibit a greater contribution of nitric oxide synthase and cyclooxygenase to β-adrenergic-medi
Exercise vasodilation is greater in women: contributions of nitric oxide synthase and cyclooxygenase
Autor:
Joshua J. Sebranek, J. Mikhail Kellawan, Rebecca E. Johansson, John W. Harrell, William G. Schrage, Marlowe W. Eldridge, Benjamin J. Walker
Publikováno v:
European Journal of Applied Physiology. 115:1735-1746
We hypothesized exercise vasodilation would be greater in women due to nitric oxide synthase (NOS) and cyclooxygenase (COX) signaling.45 healthy adults (23 women, W, 22 men, M, 26 ± 1 years) completed two 10-min trials of dynamic forearm exercise at
Autor:
Jacqueline K. Limberg, Rebecca E. Johansson, William G. Schrage, John W. Harrell, J. Mikhail Kellawan, Marlowe W. Eldridge, Joshua J. Sebranek, Lester T. Proctor
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 307:H840-H847
We tested the hypothesis that infusion of ascorbic acid (AA), a potent antioxidant, would alter vasodilator responses to exercise in human obesity and metabolic syndrome (MetSyn). Forearm blood flow (FBF, Doppler ultrasound) was measured in lean, obe
Autor:
William G. Schrage, Lester T. Proctor, Marlowe W. Eldridge, Barbara J. Morgan, Joshua J. Sebranek, Jacqueline K. Limberg
Publikováno v:
Experimental Physiology. 99:1191-1202
New Findings What is the central question of this study? α-Adrenergic-mediated vasoconstriction is greater during simulated exercise in animal models of metabolic syndrome when compared with control animals. Whether such findings can be translated t
Autor:
Rebecca E. Johansson, John W. Harrell, Marlowe W. Eldridge, Lester T. Proctor, Joshua J. Sebranek, William G. Schrage, Jacqueline K. Limberg
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 305:H1230-H1237
Older adults with cardiovascular disease exhibit microvascular dysfunction and increased levels of reactive oxygen species (ROS). We hypothesized that microvascular impairments begin early in the disease process and can be improved by scavenging ROS.
Autor:
Rebecca E. Johansson, John W. Harrell, Garrett L. Peltonen, Marlowe W. Eldridge, Joshua J. Sebranek, William G. Schrage, Benjamin J. Walker, Jeremy Kellawan, Jacqueline K. Limberg
Publikováno v:
Frontiers in Physiology
Background: β-adrenergic receptors play an important role in mitigating the pressor effects of sympathetic nervous system activity in young women. Based on recent data showing oral contraceptive use in women abolishes the relationship between muscle
Autor:
Lester T. Proctor, Marlowe W. Eldridge, Joshua J. Sebranek, William G. Schrage, Barbara J. Morgan, Benjamin J. Walker, Jacqueline K. Limberg
Publikováno v:
The Journal of Physiology. 590:6109-6119
Key points • Young healthy adults exhibit a balance between muscle sympathetic nerve activity (MSNA) and α-adrenergic-mediated vasoconstriction such that those with higher MSNA exhibit lower vascular-adrenergic responsiveness. • In contrast to h
Autor:
David F. Pegelow, Markus Amann, Jerome A. Dempsey, Gregory M. Blain, Lester T. Proctor, Joshua J. Sebranek
Publikováno v:
The Journal of Physiology. 589:5299-5309
Non-technical summary We investigated the influence of group III/IV muscle afferents on central motor drive, the development of peripheral locomotor muscle fatigue, and endurance performance time during high-intensity constant-load cycling exercise t