Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Joshua J. C. McGrath"'
Autor:
Steven P. Cass, Olivia Mekhael, Danya Thayaparan, Joshua J. C. McGrath, Spencer D. Revill, Matthew F. Fantauzzi, Peiyao Wang, Amir Reihani, Aaron I. Hayat, Christopher S. Stevenson, Anna Dvorkin-Gheva, Fernando M. Botelho, Martin R. Stämpfli, Kjetil Ask
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
RationaleThe accumulation of macrophages in the airways and the pulmonary interstitium is a hallmark of cigarette smoke-associated inflammation. Notably, pulmonary macrophages are not a homogenous population but consist of several subpopulations. To
Externí odkaz:
https://doaj.org/article/42863354dc984044af4890b5d31645bc
Autor:
L. Patrick Schenck, Joshua J. C. McGrath, Daphnée Lamarche, Martin R. Stämpfli, Dawn M. E. Bowdish, Michael G. Surette
Publikováno v:
mSphere, Vol 5, Iss 6 (2020)
ABSTRACT Respiratory infections are a leading cause of morbidity and mortality worldwide. Bacterial pathogens often colonize the upper respiratory tract (nose or mouth) prior to causing lower respiratory infections or invasive disease. Interactions w
Externí odkaz:
https://doaj.org/article/4b8080cc2100449f9a7fc427badf0db7
Autor:
Amanda J Lee, Emily Feng, Marianne V Chew, Elizabeth Balint, Sophie M Poznanski, Elizabeth Giles, Ali Zhang, Art Marzok, Spencer D Revill, Fatemeh Vahedi, Anisha Dubey, Ehab Ayaub, Rodrigo Jimenez-Saiz, Joshua J C McGrath, Tyrah M Ritchie, Manel Jordana, Danny D Jonigk, Maximilian Ackermann, Kjetil Ask, Matthew Miller, Carl D Richards, Ali A Ashkar
Publikováno v:
PLoS Pathogens, Vol 18, Iss 5, p e1010471 (2022)
The ability to treat severe viral infections is limited by our understanding of the mechanisms behind virus-induced immunopathology. While the role of type I interferons (IFNs) in early control of viral replication is clear, less is known about how I
Externí odkaz:
https://doaj.org/article/bac7c41243064cfda47eb006b0f0cc7c
Publikováno v:
Nature Immunology. 24:570-572
Autor:
Joshua J. C. McGrath, Steven P. Cass
Publikováno v:
Allergy. 77:2866-2868
Autor:
Lei Li, Siriruk Changrob, Yanbin Fu, Olivia Stovicek, Jenna J Guthmiller, Joshua J C McGrath, Haley L Dugan, Christopher T Stamper, Nai-Ying Zheng, Min Huang, Patrick C Wilson
Publikováno v:
Brief Bioinform
Artificial mutagenesis and protein engineering have laid the foundation for antigenic characterization and universal vaccine design for influenza viruses. However, many methods used in this process require manual sequence editing and protein expressi
Autor:
Joshua J C, McGrath, Danya, Thayaparan, Steven P, Cass, Jonathan P, Mapletoft, Peter Y F, Zeng, Joshua F E, Koenig, Matthew F, Fantauzzi, Puja, Bagri, Bruce, Ly, Rachel, Heo, L Patrick, Schenck, Pamela, Shen, Matthew S, Miller, Martin R, Stämpfli
Publikováno v:
Mucosal immunology. 14(5)
The upper respiratory tract is highly exposed to airborne pathogens and serves as an important inductive site for protective antibody responses, including mucosal IgA and systemic IgG. However, it is currently unknown to what extent inhaled environme