Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Joshua J White"'
Autor:
Gerrit Cornelis Beekhof, Catarina Osório, Joshua J White, Scott van Zoomeren, Hannah van der Stok, Bilian Xiong, Ingo HMS Nettersheim, Willem Ashwin Mak, Marit Runge, Francesca Romana Fiocchi, Henk-Jan Boele, Freek E Hoebeek, Martijn Schonewille
Publikováno v:
eLife, Vol 10 (2021)
Distinct populations of Purkinje cells (PCs) with unique molecular and connectivity features are at the core of the modular organization of the cerebellum. Previously, we showed that firing activity of PCs differs between ZebrinII-positive and Zebrin
Externí odkaz:
https://doaj.org/article/3e63f4188e7347519436936b6269724f
Publikováno v:
eLife, Vol 9 (2020)
Tremor is currently ranked as the most common movement disorder. The brain regions and neural signals that initiate the debilitating shakiness of different body parts remain unclear. Here, we found that genetically silencing cerebellar Purkinje cell
Externí odkaz:
https://doaj.org/article/d5e00430d77a429dabb1d539cbd5821e
Autor:
Joshua J White, Roy V Sillitoe
Publikováno v:
Frontiers in Neuroanatomy, Vol 7 (2013)
The cerebellum is organized into parasagittal zones that control sensory-motor behavior. Although the architecture of adult zones is well understood, very little is known about how zones emerge during development. Understanding the process of zone fo
Externí odkaz:
https://doaj.org/article/59b8638616d6452ba21d6013fdcc550d
Publikováno v:
Frontiers in Neural Circuits, Vol 6 (2013)
The cerebellum has a simple tri-laminar structure that is comprised of relatively few cell types. Yet, its internal micro-circuitry is anatomically, biochemically, and functionally complex. The most striking feature of cerebellar circuit complexity i
Externí odkaz:
https://doaj.org/article/2718ae7d43384ce5903b3f4b90a6980a
Autor:
François G. C. Blot, Joshua J. White, Amy van Hattem, Licia Scotti, Vaishnavi Balaji, Youri Adolfs, R. Jeroen Pasterkamp, Chris I. De Zeeuw, Martijn Schonewille
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract The classification of neuronal subpopulations has significantly advanced, yet its relevance for behavior remains unclear. The highly organized flocculus of the cerebellum, known to fine-tune multi-axial eye movements, is an ideal substrate f
Externí odkaz:
https://doaj.org/article/82fd7fa96c6f48598a238a279fec019b
Autor:
Stijn Voerman, Bastiaan H. A. Urbanus, Martijn Schonewille, Joshua J. White, Chris I. De Zeeuw
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-7 (2022)
Electrophysiological recordings from Purkinje cells in mice show that the potential for induction of long-term depression may vary with molecular identity
Externí odkaz:
https://doaj.org/article/c0ec630b4ec84d1eb41d28615d3d4808
Autor:
François G. C. Blot, Joshua J. White, Amy van Hattem, Licia Scotti, Vaishnavi Balaji, Youri Adolfs, R. Jeroen Pasterkamp, Chris I. De Zeeuw, Martijn Schonewille
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/4a38a20ffeec4897acf957e5eea2c06c
Autor:
Lisanne J. van’t Sant, Joshua J. White, Jan H. J. Hoeijmakers, Wilbert P. Vermeij, Dick Jaarsma
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-20 (2021)
Abstract Fluorescent staining of newly transcribed RNA via metabolic labelling with 5-ethynyluridine (EU) and click chemistry enables visualisation of changes in transcription, such as in conditions of cellular stress. Here, we tested whether EU labe
Externí odkaz:
https://doaj.org/article/ef45f63d26b14d52901530cdf2a81f48
Autor:
Lauren N. Miterko, Tao Lin, Joy Zhou, Meike E. van der Heijden, Jaclyn Beckinghausen, Joshua J. White, Roy V. Sillitoe
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Deep brain stimulation (DBS) has potential for several movement disorders. Here the authors show that DBS improves motor function in a mouse model of ataxia.
Externí odkaz:
https://doaj.org/article/65cc25c011ad4bb78bf25ac8b3f1001d
Publikováno v:
Journal of the American College of Emergency Physicians Open, Vol 2, Iss 1, Pp n/a-n/a (2021)
Externí odkaz:
https://doaj.org/article/eef9b8883294438e9730c88aed4b2373