Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Joshua J Obar"'
Autor:
Joshua J Obar, Kelly M Shepardson
Publikováno v:
PLoS Pathogens, Vol 19, Iss 5, p e1011334 (2023)
Externí odkaz:
https://doaj.org/article/62064dde430644db85fcee58b6dcd9e2
Autor:
Yuko Kawakami, Miho Kimura, Christella Widjaja, Kazumi Kasakura, Tomoaki Ando, Yu Kawakami, Joshua J. Obar, Toshiaki Kawakami
Publikováno v:
Frontiers in Allergy, Vol 4 (2023)
BackgroundMast cells are the major effector cell type for IgE-mediated allergic reactions. Recent studies revealed a role for mast cells in orchestrating the host response to viral infections.ObjectiveWe studied the relationship between FcεRI (high-
Externí odkaz:
https://doaj.org/article/83f844f57edb4479a6817cde381d5320
Autor:
Ko-Wei Liu, Madeleine S. Grau, Jane T. Jones, Xi Wang, Elisa M. Vesely, Matthew R. James, Cecilia Gutierrez-Perez, Robert A. Cramer, Joshua J. Obar
Publikováno v:
mBio, Vol 13, Iss 6 (2022)
ABSTRACT Aspergillus fumigatus is a human fungal pathogen that is most often avirulent in immunecompetent individuals because the innate immune system is efficient at eliminating fungal conidia. However, recent clinical observations have shown that s
Externí odkaz:
https://doaj.org/article/0dbf20e9d99a4ffaba87096a512d23d2
Autor:
Marina E. Kirkland, McKenzie Stannard, Caitlin H. Kowalski, Dallas Mould, Alayna Caffrey-Carr, Rachel M. Temple, Brandon S. Ross, Lotus A. Lofgren, Jason E. Stajich, Robert A. Cramer, Joshua J. Obar
Publikováno v:
mSphere, Vol 6, Iss 6 (2021)
ABSTRACT Aspergillus fumigatus isolates display significant heterogeneity in growth, virulence, pathology, and inflammatory potential in multiple murine models of invasive aspergillosis. Previous studies have linked the initial germination of a funga
Externí odkaz:
https://doaj.org/article/a9d97d6657df4007937c146b431aced9
Autor:
Benjamin AWR Ralph, Melanie Lehoux, Hanna Ostapska, Brendan D. Snarr, Alayna K. Caffrey-Carr, Richard Fraser, Maya Saleh, Joshua J. Obar, Salman T. Qureshi, Donald C. Sheppard
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Aspergillus fumigatus airway infections are associated with increased rates of hospitalizations and declining lung function in patients with chronic lung disease. While the pathogenesis of invasive A. fumigatus infections is well studied, little is k
Externí odkaz:
https://doaj.org/article/d88a9100c3c944109606726bf7d86365
Autor:
Jane T. Jones, Ko-Wei Liu, Xi Wang, Caitlin H. Kowalski, Brandon S. Ross, Kathleen A. M. Mills, Joshua D. Kerkaert, Tobias M. Hohl, Lotus A. Lofgren, Jason E. Stajich, Joshua J. Obar, Robert A. Cramer
Publikováno v:
mSphere, Vol 6, Iss 1 (2021)
Allergic broncho-pulmonary aspergillosis (ABPA) patients often present with long-term colonization of Aspergillus fumigatusin vivo
Externí odkaz:
https://doaj.org/article/2d51c477fd3c4b37918cee6177e1c4da
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/44e9181f82bd4e8bb402cbc68c15116e
Autor:
Laure Nicolas Annick Ries, Jacob L. Steenwyk, Patrícia Alves de Castro, Pollyne Borborema Almeida de Lima, Fausto Almeida, Leandro José de Assis, Adriana Oliveira Manfiolli, Azusa Takahashi-Nakaguchi, Yoko Kusuya, Daisuke Hagiwara, Hiroki Takahashi, Xi Wang, Joshua J. Obar, Antonis Rokas, Gustavo H. Goldman
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Acquisition and subsequent metabolism of different carbon and nitrogen sources have been shown to play an important role in virulence attributes of the fungal pathogen Aspergillus fumigatus, such as the secretion of host tissue-damaging proteases and
Externí odkaz:
https://doaj.org/article/7d53cea0f9684301979ff08fa8f08ed6
Autor:
Alayna K. Caffrey-Carr, Kimberly M. Hilmer, Caitlin H. Kowalski, Kelly M. Shepardson, Rachel M. Temple, Robert A. Cramer, Joshua J. Obar
Publikováno v:
Frontiers in Immunology, Vol 8 (2018)
Aspergillus fumigatus is a mold that causes severe pulmonary infections. Our knowledge of how immune competent hosts maintain control of fungal infections while constantly being exposed to fungi is rapidly emerging. It is known that timely neutrophil
Externí odkaz:
https://doaj.org/article/7411fbe98c034d999cb689b440db9e7c
Autor:
Ko-Wei Liu, Madeleine S. Grau, Jane T. Jones, Xi Wang, Elisa M. Vesely, Matthew R. James, Cecilia Gutierrez-Perez, Robert A. Cramer, Joshua J. Obar
Aspergillus fumigatusis a human fungal pathogen that is most often avirulent in immune competent individuals because the innate immune system is efficient at eliminating fungal conidia. However, recent clinical observations have shown that severe Inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb83046d6215491b1e32639209b76a45
https://doi.org/10.1101/2022.10.14.512336
https://doi.org/10.1101/2022.10.14.512336
