Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Joshua J Emrick"'
Autor:
Sienna K. Perry, Joshua J. Emrick
Publikováno v:
Frontiers in Pain Research, Vol 5 (2024)
Externí odkaz:
https://doaj.org/article/e798fc8fc7c8416785784e11e5f84195
Autor:
Sienna K. Perry, Joshua J. Emrick
Publikováno v:
Frontiers in Pain Research, Vol 5 (2024)
The temporomandibular joint (TMJ) consists of bone, cartilage, ligaments, and associated masticatory muscles and tendons that coordinate to enable mastication in mammals. The TMJ is innervated by the trigeminal nerve (CNV), containing axons of motor
Externí odkaz:
https://doaj.org/article/a718aa5b988a42109c9f5a479136c3f7
Publikováno v:
Frontiers in Pain Research, Vol 5 (2024)
Somatosensory innervation of the oral cavity enables the detection of a range of environmental stimuli including minute and noxious mechanical forces. The trigeminal sensory neurons underlie sensation originating from the tooth. Prior work has provid
Externí odkaz:
https://doaj.org/article/c9cb865a24514fc482202c048e1f536c
Autor:
Sarah B Peters, Joshua J Emrick
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 7, Pp 1503-1504 (2023)
Externí odkaz:
https://doaj.org/article/6f5ad85532ce430b9cb126a5fcd1ba25
Autor:
Alexander T. Chesler, Nicholas J. P. Ryba, Ruby M. Lam, Joshua J. Emrick, Lars J. von Buchholtz
Publikováno v:
Pain
Single cell sequencing has provided unprecedented information about the transcriptomic diversity of somatosensory systems. Here, we describe a simple and versatile in situ hybridization (ISH)-based approach for mapping this information back to the ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ecd03244d1b5294a732d5f29dcfce9b
https://doi.org/10.1097/j.pain.0000000000001911
https://doi.org/10.1097/j.pain.0000000000001911
Publikováno v:
J Dent Res
Toothache is a common painful consequence of damage to the teeth, particularly when coupled to infection. Clinical restoration of tooth integrity, sometimes involving physical and chemical sterilization of the tooth with nerve fiber ablation (i.e., e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c080ddbcb20a09d23c30b40019c7669f
https://europepmc.org/articles/PMC7684839/
https://europepmc.org/articles/PMC7684839/
Autor:
John V. Lin King, David Julius, Mark J. S. Kelly, Joshua J. Emrick, Volker Herzig, Glenn F. King, Katalin F. Medzihradszky
Publikováno v:
Cell
Cell, vol 178, iss 6
Cell, vol 178, iss 6
TRPA1 is a chemosensory ion channel that functions as a sentinel for structurally diverse electrophilic irritants. Channel activation occurs through an unusual mechanism involving covalent modification of cysteine residues clustered within an amino-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::089d3cb9654169e2499251e36b639cea
https://europepmc.org/articles/PMC6731142/
https://europepmc.org/articles/PMC6731142/
Autor:
Andy D. Weyer, Eivind A. B. Undheim, Frank Bosmans, Chuchu Zhang, Jeremiah D. Osteen, Grigori Y. Rychkov, John Gilchrist, Glenn F. King, David Julius, Allan I. Basbaum, Luke Grundy, Cheryl L. Stucky, Stuart M. Brierley, Zoltan Dekan, Xidao Wang, Paul F. Alewood, Joel Castro, Sonia Garcia-Caraballo, Joshua J. Emrick, Volker Herzig
Publikováno v:
Nature
Voltage-gated sodium (Na-v) channels initiate action potentials in most neurons, including primary afferent nerve fibres of the pain pathway. Local anaesthetics block pain through non-specific actions at all Na-v channels, but the discovery of select
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::111e278a95f5de7f9a87efe3eee05a95
http://europepmc.org/articles/PMC4919188
http://europepmc.org/articles/PMC4919188
Autor:
Joshua J, Emrick, Anubhav, Mathur, Jessica, Wei, Elena O, Gracheva, Karsten, Gronert, Michael D, Rosenblum, David, Julius
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 115(51)
Atopic dermatitis (AD) is the most common skin disease in children. It is characterized by relapsing inflammation, skin-barrier defects, and intractable itch. However, the pathophysiology of itch in AD remains enigmatic. Here, we examine the contribu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::787a080af5e92b324c8dee79b83ae12c
https://pubmed.ncbi.nlm.nih.gov/30538205
https://pubmed.ncbi.nlm.nih.gov/30538205
Autor:
Michael Rosenblum, Jessica Wei, Elena O. Gracheva, David Julius, Karsten Gronert, Joshua J. Emrick, Anubhav N. Mathur
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 115, iss 51
Atopic dermatitis (AD) is the most common skin disease in children. It is characterized by relapsing inflammation, skin-barrier defects, and intractable itch. However, the pathophysiology of itch in AD remains enigmatic. Here, we examine the contribu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5460d1db3bb726fdc2a63057cee1a5d8
https://doi.org/10.1073/pnas.1814132115
https://doi.org/10.1073/pnas.1814132115