Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Joshua Hislop"'
Autor:
Dongshunyi Li, Jeremy J. Velazquez, Jun Ding, Joshua Hislop, Mo R. Ebrahimkhani, Ziv Bar-Joseph
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-19 (2022)
Abstract A major advantage of single cell RNA-sequencing (scRNA-Seq) data is the ability to reconstruct continuous ordering and trajectories for cells. Here we present TraSig, a computational method for improving the inference of cell-cell interactio
Externí odkaz:
https://doaj.org/article/8b97f126d0ac4d28a579e15ac820ce67
Autor:
Joseph C Maggiore, Ryan LeGraw, Aneta Przepiorski, Jeremy Velazquez, Christopher Chaney, Evan Streeter, Anne Silva-Barbosa, Jonathan Franks, Joshua Hislop, Alex Hill, Haojia Wu, Katherine Pfister, Sara E Howden, Simon C Watkins, Melissa Little, Benjamin Humphreys, Alan Watson, Donna B Stolz, Samira Kiani, Alan J Davidson, Thomas J. Carroll, Ondine J. Cleaver, Sunder Sims-Lucas, Mo R Ebrahimkhani, Neil A Hukriede
Vascularization plays a critical role in organ maturation and cell type development. Drug discovery, organ mimicry, and ultimately transplantation in a clinical setting thereby hinges on achieving robust vascularization of in vitro engineered organs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a832bb2fd956b83cba53f6fdf775582
https://doi.org/10.1101/2023.05.30.542848
https://doi.org/10.1101/2023.05.30.542848
Autor:
Jeremy J. Velazquez, Dongshunyi Li, Ziv Bar-Joseph, Jun Ding, Mo R. Ebrahimkhani, Joshua Hislop
A major advantage of single cell RNA-Sequencing (scRNA-Seq) data is the ability to reconstruct continuous ordering and trajectories for cells. To date, such ordering was mainly used to group cells and to infer interactions within cells. Here we prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45c4735b288c919a9b624d3dede710c8
https://doi.org/10.1101/2021.07.28.454054
https://doi.org/10.1101/2021.07.28.454054
Autor:
Farzaneh Moghadam, Yuqi Tan, Silvia Liu, Susana M. Chuva de Sousa Lopes, Mo R. Ebrahimkhani, Joseph C. Maggiore, Joshua Hislop, Jeremy J. Velazquez, Davy Cats, Patrick Cahan, Christopher L. Plaisier, Ryan LeGraw, Samira Kiani, Jacquelyn Kilbourne
Publikováno v:
Cell Systems, 12(1), 41-55.e11. Elsevier
Trends Genet
Trends Genet
Summary Pluripotent stem cell (PSC)-derived organoids have emerged as novel multicellular models of human tissue development but display immature phenotypes, aberrant tissue fates, and a limited subset of cells. Here, we demonstrate that integrated a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef984817d983a940da7411dc9fc419ff
http://hdl.handle.net/1887/3280148
http://hdl.handle.net/1887/3280148
Publikováno v:
Methods in Molecular Biology ISBN: 9781071611739
Methods Mol Biol
Methods Mol Biol
Cell-fate determination is a function of cell-intrinsic and -extrinsic signaling cues. Understanding the design principles governing fate control in multicellular systems remains difficult to understand and analyze. To address the current challenges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d25910863e8cfcf1900443e3fa2820f8
https://doi.org/10.1007/978-1-0716-1174-6_2
https://doi.org/10.1007/978-1-0716-1174-6_2
Autor:
Jeremy J. Velazquez, Shi Tong Liu, Jacquelyn Kilbourne, Farzaneh Moghadam, Christopher L. Plaisier, Yuqi Tan, Ryan LeGraw, Mo R. Ebrahimkhani, Davy Cats, Susana M. Chuva de Sousa Lopes, Joshua Hislop, Samira Kiani, Patrick Cahan
SUMMARYPluripotent stem cell (PSC)-derived organoids are emerging as novel human-based microphysiological models but display immature phenotypes with limited subsets of endothelial or stromal cells. Here we demonstrate that in vitro manipulation of g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b90a728c6249b275459fecc216928cf9