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pro vyhledávání: '"Joshua Grabeck"'
Autor:
Denise Meinberger, Marco G. Drexelius, Joshua Grabeck, Gabriele Hermes, Annika Roth, Dzemal Elezagic, Ines Neundorf, Thomas Streichert, Andreas R. Klatt
Publikováno v:
Antibiotics, Vol 12, Iss 10, p 1532 (2023)
Antimicrobial peptides (AMPs) represent a promising alternative to conventional antibiotics. Sequence changes can significantly improve the therapeutic properties of antimicrobial peptides. In our study, we apply different sequence modifications to e
Externí odkaz:
https://doaj.org/article/443eba95fde3488bb2fa481aff721d14
Publikováno v:
Molecules, Vol 27, Iss 19, p 6656 (2022)
Herein, the design and synthesis of peptide-drug conjugates (PDCs) including different variants of the cell-penetrating peptide sC18 is presented. We first generated a series of novel sequence mutants of sC18 having either amino acid deletions and/or
Externí odkaz:
https://doaj.org/article/58b011ca411848509644073ebcce86aa
Autor:
Joshua Grabeck, Andre Reinhardt, Tom Cronenberg, Frank Nitsche, Berenike Maier, Pitter F. Huesgen, Ines Neundorf, Marco Drexelius
Publikováno v:
Biochemical journal 478(1), 63-78 (2021). doi:10.1042/BCJ20200698
Multidrug resistant (MDR) bacteria have adapted to most clinical antibiotics and are a growing threat to human health. One promising type of candidates for the everlasting demand of new antibiotic compounds constitute antimicrobial peptides (AMPs). T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15c68f114eef7fa07cba67ed8502a802
https://pubmed.ncbi.nlm.nih.gov/33313751
https://pubmed.ncbi.nlm.nih.gov/33313751