Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Joshua Gillard"'
Autor:
Joshua Gillard, Madeleine Suffiotti, Peter Brazda, Prashanna B. Venkatasubramanian, Pauline Versteegen, Marien I. de Jonge, Dominic Kelly, Sagida Bibi, Marta Valente Pinto, Elles Simonetti, Mihaela Babiceanu, Andrew Kettring, Cristina Teodosio, Ronald de Groot, Guy Berbers, Hendrik G. Stunnenberg, Brian Schanen, Craig Fenwick, Martijn A. Huynen, Dimitri A. Diavatopoulos
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Many countries continue to experience pertussis epidemics despite widespread vaccination. Waning protection after booster vaccination has highlighted the need for a better understanding of the immunological factors that promote durable prote
Externí odkaz:
https://doaj.org/article/070c1fead68940ffb909a241214acbe3
Autor:
Jakob Einhaus, Dyani K. Gaudilliere, Julien Hedou, Dorien Feyaerts, Michael G. Ozawa, Masaki Sato, Edward A. Ganio, Amy S. Tsai, Ina A. Stelzer, Karl C. Bruckman, Jonas N. Amar, Maximilian Sabayev, Thomas A. Bonham, Joshua Gillard, Maïgane Diop, Amelie Cambriel, Zala N. Mihalic, Tulio Valdez, Stanley Y. Liu, Leticia Feirrera, David K. Lam, John B. Sunwoo, Christian M. Schürch, Brice Gaudilliere, Xiaoyuan Han
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108486- (2023)
Summary: Oral squamous cell carcinoma (OSCC), a prevalent and aggressive neoplasm, poses a significant challenge due to poor prognosis and limited prognostic biomarkers. Leveraging highly multiplexed imaging mass cytometry, we investigated the tumor
Externí odkaz:
https://doaj.org/article/869544f8ba5e4b78a97cd60fb2d44b05
Autor:
Evi van Schuppen, Janeri Fröberg, Prashanna Balaji Venkatasubramanian, Pauline Versteegen, Hans de Graaf, Jana Holubová, Joshua Gillard, Pieter G. M. van Gageldonk, Irma Joosten, Ronald de Groot, Peter Šebo, Guy A. M. Berbers, Robert C. Read, Martijn A. Huynen, Marien I. de Jonge, Dimitri A. Diavatopoulos
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Bordetella pertussis (Bp), the causative agent of pertussis, continues to circulate and it’s not well understood how (sub)clinical infections shape immune memory to Bp and vaccination. Here, using a mutant Bp strain lacking antigens of the acellula
Externí odkaz:
https://doaj.org/article/89b65445de2a46a88e026c42b7c1a8cc
Autor:
Isaac Núñez, Joshua Gillard, Sergio Fragoso-Saavedra, Dorien Feyaerts, León Islas-Weinstein, Angel A. Gallegos-Guzmán, Uriel Valente-García, Justin Meyerowitz, J. Daniel Kelly, Han Chen, Edward Ganio, Alexander Benkendorff, Jaime Flores-Gouyonnet, Pedro Dammann-Beltrán, José Francisco Heredia-González, Gabriela A. Rangel-Gutiérrez, Catherine A. Blish, Kari C. Nadeau, Garry Nolan, Jose C. Crispín, David R. McIlwain, Brice Gaudillière, Sergio I. Valdés-Ferrer
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
IntroductionFew studies have evaluated the presence of Post COVID-19 conditions (PCC) in people from Latin America, a region that has been heavily afflicted by the COVID-19 pandemic. In this study, we describe the frequency, co-occurrence, predictors
Externí odkaz:
https://doaj.org/article/0bb7fe6b72c541e9aab5fef4af1187ca
Autor:
Joshua Gillard, Bastiaan A. Blok, Daniel R. Garza, Prashanna Balaji Venkatasubramanian, Elles Simonetti, Marc J. Eleveld, Guy A. M. Berbers, Pieter G. M. van Gageldonk, Irma Joosten, Ronald de Groot, L. Charlotte J. de Bree, Reinout van Crevel, Marien I. de Jonge, Martijn A. Huynen, Mihai G. Netea, Dimitri A. Diavatopoulos
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-9 (2022)
Abstract Acellular pertussis (aP) booster vaccines are central to pertussis immunization programs, although their effectiveness varies. The Bacille Calmette-Guérin (BCG) vaccine is a prototype inducer of trained immunity, which enhances immune respo
Externí odkaz:
https://doaj.org/article/03fd26af521743d3bf22ca86c1c84e94
Autor:
Janeri Fröberg, Joshua Gillard, Ria Philipsen, Kjerstin Lanke, Joyce Rust, Diana van Tuijl, Karina Teelen, Teun Bousema, Elles Simonetti, Christa E. van der Gaast-de Jongh, Mariska Bos, Frank J. van Kuppeveld, Berend-Jan Bosch, Marrigje Nabuurs-Franssen, Nannet van der Geest-Blankert, Charlotte van Daal, Martijn A. Huynen, Marien I. de Jonge, Dimitri A. Diavatopoulos
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
There has been limited research on the role of the mucosal immune response to SARS-CoV-2 infection. Here, the authors perform a prospective observational household study and find that mucosal antibody responses are associated with decreased viral loa
Externí odkaz:
https://doaj.org/article/50f02a2039984e818d1c4dc6db699767
Autor:
Dorien Feyaerts, Joshua Gillard, Bram van Cranenbroek, Lina Rigodanzo Marins, Mariam M. S. Baghdady, Gaia Comitini, A. Titia Lely, Henk W. van Hamersvelt, Olivier W. H. van der Heijden, Irma Joosten, Renate G. van der Molen
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Pregnancy after renal transplantation is associated with an increased risk of complications. While a delicately balanced uterine immune system is essential for a successful pregnancy, little is known about the uterine immune environment of pregnant k
Externí odkaz:
https://doaj.org/article/55dbb48733504b01ac7f3ae3d4bf7556
Autor:
Simone J.C.F.M. Moorlag, Yessica Alina Rodriguez-Rosales, Joshua Gillard, Stephanie Fanucchi, Kate Theunissen, Boris Novakovic, Cynthia M. de Bont, Yutaka Negishi, Ezio T. Fok, Lydia Kalafati, Panayotis Verginis, Vera P. Mourits, Valerie A.C.M. Koeken, L. Charlotte J. de Bree, Ger J.M. Pruijn, Craig Fenwick, Reinout van Crevel, Leo A.B. Joosten, Irma Joosten, Hans Koenen, Musa M. Mhlanga, Dimitri A. Diavatopoulos, Triantafyllos Chavakis, Mihai G. Netea
Publikováno v:
Cell Reports, Vol 33, Iss 7, Pp 108387- (2020)
Summary: The tuberculosis vaccine bacillus Calmette-Guérin (BCG) protects against some heterologous infections, probably via induction of non-specific innate immune memory in monocytes and natural killer (NK) cells, a process known as trained immuni
Externí odkaz:
https://doaj.org/article/867252fa4e9041d0b4262603d849461e
Autor:
Anne Zeddeman, Evi van Schuppen, Kristianne E Kok, Marjolein van Gent, Kees J Heuvelman, Marieke J Bart, Han G J van der Heide, Joshua Gillard, Elles Simonetti, Marc J Eleveld, Fred J H van Opzeeland, Saskia van Selm, Ronald de Groot, Marien I de Jonge, Frits R Mooi, Dimitri A Diavatopoulos
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0237394 (2020)
Bordetella pertussis vaccine escape mutants that lack expression of the pertussis antigen pertactin (Prn) have emerged in vaccinated populations in the last 10-20 years. Additionally, clinical isolates lacking another acellular pertussis (aP) vaccine
Externí odkaz:
https://doaj.org/article/7b2d2994431c417db634287736b3d67c
Autor:
Felix Hugentobler, Karen K Yam, Joshua Gillard, Raya Mahbuba, Martin Olivier, Benoit Cousineau
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30945 (2012)
Leishmania is a mammalian parasite affecting over 12 million individuals worldwide. Current treatments are expensive, cause severe side effects, and emerging drug resistance has been reported. Vaccination is the most cost-effective means to control i
Externí odkaz:
https://doaj.org/article/4580f8cc58f342cc852efa7771c5225c