Výsledky vyhledávání - "Joshua Gervin"

Akademický článek

Leveraging gene correlations in single cell transcriptomic data

Autor: Kai Silkwood, Emmanuel Dollinger, Joshua Gervin, Scott Atwood, Qing Nie, Arthur D. Lander

Publikováno v: BMC Bioinformatics, Vol 25, Iss 1, Pp 1-43 (2024)

Abstract Background Many approaches have been developed to overcome technical noise in single cell RNA-sequencing (scRNAseq). As researchers dig deeper into data—looking for rare cell types, subtleties of cell states, and details of gene regulatory

Externí odkaz: https://doaj.org/article/1c805c6f0a6e47c8a01756342320121c

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Akademický článek

Survival of the Curviest: Noise-Driven Selection for Synergistic Epistasis.

Autor: Jon F Wilkins, Peter T McHale, Joshua Gervin, Arthur D Lander

Publikováno v: PLoS Genetics, Vol 12, Iss 4, p e1006003 (2016)

A major goal of human genetics is to elucidate the genetic architecture of human disease, with the goal of fueling improvements in diagnosis and the understanding of disease pathogenesis. The degree to which epistasis, or non-additive effects of risk

Externí odkaz: https://doaj.org/article/20bd7529e610485eb09cb4a39375994c

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Akademický článek

Postinjection delirium/sedation syndrome in a transgender man undergoing hormone therapy

Autor: Joshua Gerving, PharmD, BCPS, BCPP, Heather Walser, PharmD, BCPP, Anne C. Kelly, MD

Publikováno v: Mental Health Clinician, Vol 12, Iss 4, Pp 263-266 (2023)

Background: Long-acting injectable medications have become an important tool in the treatment of schizophrenia and schizoaffective disorder due to the high rates of medication nonadherence. Olanzapine long-acting injection (OLAI) is a useful therapeu

Externí odkaz: https://doaj.org/article/1824c0a8ad7e4d28beed3c1334680f0b

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Survival of the Curviest: Noise-Driven Selection for Synergistic Epistasis

Autor: Joshua Gervin, Peter McHale, Jon F. Wilkins, Arthur D. Lander

Publikováno v: PLoS genetics, vol 12, iss 4
PLoS Genetics
Wilkins, JF; McHale, PT; Gervin, J; & Lander, AD. (2016). Survival of the Curviest: Noise-Driven Selection for Synergistic Epistasis. PLOS GENETICS, 12(4), e1006003. doi: 10.1371/journal.pgen.1006003. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/90d512kr
PLoS Genetics, Vol 12, Iss 4, p e1006003 (2016)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6b1bd14717d5f37105d55c3d1352872
https://escholarship.org/uc/item/90d512kr

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Discovering regulatory motifs in the Plasmodium genome using comparative genomics

Autor: Xiaohui Xie, Douglas H. Sieglaff, Joshua Gervin, Jie Wu

Publikováno v: Bioinformatics (Oxford, England). 24(17)

Motivation: Understanding gene regulation in Plasmodium, the causative agent of malaria, is an important step in deciphering its complex life cycle as well as leading to possible new targets for therapeutic applications. Very little is known about ge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3edf59b9ef2c1f524d4d6c1b48b05553
https://pubmed.ncbi.nlm.nih.gov/18611947

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