Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Joshua G. Puhl"'
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0201206 (2018)
The medicinal leech is one of the most venerated model systems for the study of fundamental nervous system principles, ranging from single-cell excitability to complex sensorimotor integration. Yet, molecular analyses have yet to be extensively appli
Externí odkaz:
https://doaj.org/article/fd6adcd65deb4c9bb2f502da03702660
Publikováno v:
eLife, Vol 6 (2017)
Motoneurons are traditionally viewed as the output of the spinal cord that do not influence locomotor rhythmogenesis. We assessed the role of motoneuron firing during ongoing locomotor-like activity in neonatal mice expressing archaerhopsin-3 (Arch),
Externí odkaz:
https://doaj.org/article/31316c11901a47438854f42db0fa15ae
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 7, p e0201206 (2018)
PLoS ONE, Vol 13, Iss 7, p e0201206 (2018)
The medicinal leech is one of the most venerated model systems for the study of fundamental nervous system principles, ranging from single-cell excitability to complex sensorimotor integration. Yet, molecular analyses have yet to be extensively appli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae179ce5e6d6ee805ec4be85818f79fc
http://europepmc.org/articles/PMC6054404
http://europepmc.org/articles/PMC6054404
Publikováno v:
eNeuro
Many animals depend on descending information from the brain for the initiation and proper execution of locomotion. Interestingly, after injury and the loss of such inputs, locomotor function can sometimes be regained without the regrowth of central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dfca635c2bfd282b4b7f6e3c0cf95ff
http://europepmc.org/articles/PMC6071192
http://europepmc.org/articles/PMC6071192
Publikováno v:
The Journal of experimental biology. 221(Pt 7)
Blood feeding is an essential and signature activity of the medicinal leech species H irudo verbana . Despite keen interest in understanding the neuronal substrates of this behavior, a major component of the nervous system associated with feeding has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::102bc2abcd51c98faf70f186b40efd57
https://pubmed.ncbi.nlm.nih.gov/29444844
https://pubmed.ncbi.nlm.nih.gov/29444844
Publikováno v:
The Journal of Neuroscience. 32:17646-17657
In this report we posed the overarching question: What multiple contributions can a single neuron have on controlling the behavior of an animal, especially within a given context? To address this timely question, we studied the neuron R3b-1 in the me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0247cf03c1367f7117bbe5987e6929a6
https://doi.org/10.1523/jneurosci.2249-12.2012
https://doi.org/10.1523/jneurosci.2249-12.2012
Autor:
Joshua G. Puhl, Karen A. Mesce
Publikováno v:
The Journal of Neuroscience. 30:2373-2383
The coordination of multiple neural oscillators is key for the generation of productive locomotor movements. In the medicinal leech, we determined that activation and coordination of the segmental crawl oscillators, or unit burst generators, are depe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74d8390621b1a0fd9fa461d5a054a25f
https://doi.org/10.1523/jneurosci.5765-09.2010
https://doi.org/10.1523/jneurosci.5765-09.2010
Autor:
Karen A. Mesce, Joshua G. Puhl
Publikováno v:
The Journal of Neuroscience. 28:4192-4200
Locomotion in segmented animals is thought to be based on the coupling of "unit burst generators," but the biological nature of the unit burst generator has been revealed in only a few animal systems. We determined that dopamine (DA), a universal mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8aca0d6a42558e03358c6263fada027
https://doi.org/10.1523/jneurosci.0136-08.2008
https://doi.org/10.1523/jneurosci.0136-08.2008
Autor:
Christian Nagel, Emma Morley, Chantel Schlegel, Karen A. Mesce, Chris Stewart, Joshua G. Puhl, Melissa G. Reilly, Cynthia M. Harley, Kevin M. Crisp
Publikováno v:
Journal of neurophysiology. 113(10)
Homeostatic plasticity is an important attribute of neurons and their networks, enabling functional recovery after perturbation. Furthermore, the directed nature of this plasticity may hold a key to the restoration of locomotion after spinal cord inj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aa9894b1b37987952f50757aa8cda91
https://pubmed.ncbi.nlm.nih.gov/26424582
https://pubmed.ncbi.nlm.nih.gov/26424582