Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Joshua G. Liang"'
Autor:
Joshua G. Liang, Danmei Su, Tian-Zhang Song, Yilan Zeng, Weijin Huang, Jinhua Wu, Rong Xu, Peiwen Luo, Xiaofang Yang, Xiaodong Zhang, Shuangru Luo, Ying Liang, Xinglin Li, Jiaju Huang, Qiang Wang, Xueqin Huang, Qingsong Xu, Mei Luo, Anliang Huang, Dongxia Luo, Chenyan Zhao, Fan Yang, Jian-Bao Han, Yong-Tang Zheng, Peng Liang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Vaccines for SARS-CoV-2 are needed to fight the pandemic. Here the authors show immunogenicity of an adjuvanted subunit vaccine, SARS-CoV-2 spike protein trimerized with trimer-tag technology, in small animal models and protection from SARS-CoV-2 cha
Externí odkaz:
https://doaj.org/article/61db57e69d5a405e82b86f6070a7345d
Autor:
Haipeng Liu, Danmei Su, Jinlong Zhang, Shuaishuai Ge, Youwei Li, Fei Wang, Michel Gravel, Anne Roulston, Qin Song, Wei Xu, Joshua G. Liang, Gordon Shore, Xiaodong Wang, Peng Liang
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract TNF-related apoptosis-inducing ligand (TRAIL/Apo2L) has long been considered a tantalizing target for cancer therapy because it mediates activation of the extrinsic apoptosis pathway in a tumor-specific manner by binding to and trimerizing i
Externí odkaz:
https://doaj.org/article/689ba978ac0b499ca617fd53fe206c90
Autor:
Yang Xu, Lingmo Chang, Anliang Huang, Xiaojun Liu, Xinyu Liu, Hong Zhou, Joshua G. Liang, Peng Liang
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
Abstract Aberrant expression of TNF family of cytokines has been linked to human diseases, and biologics targeting their signaling have become the best selling drugs globally. However, functional detection with labeled ligands for accurate detection
Externí odkaz:
https://doaj.org/article/4cdf3414717f4446a182075804eda027
Autor:
Yang Xu, Lingmo Chang, Anliang Huang, Xiaojun Liu, Xinyu Liu, Hong Zhou, Joshua G. Liang, Peng Liang
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-1 (2018)
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
Externí odkaz:
https://doaj.org/article/38f9d053b9d64e59882effc528128690
Autor:
Qingsong Xu, Xueqin Huang, Xinglin Li, Xiaodong Zhang, Shuangru Luo, Jiaju Huang, Ying Liang, Xiaofang Yang, Tian-Zhang Song, Qiang Wang, Jian-Bao Han, Danmei Su, Rong Xu, Fan Yang, Anliang Huang, Joshua G. Liang, Mei Luo, Peiwen Luo, Yong-Tang Zheng, Weijin Huang, Yilan Zeng, Dongxia Luo, Peng Liang, Chenyan Zhao, Jinhua Wu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications
Nature Communications
SARS-CoV-2 is the underlying cause for the COVID-19 pandemic. Like most enveloped RNA viruses, SARS-CoV-2 uses a homotrimeric surface antigen to gain entry into host cells. Here we describe S-Trimer, a native-like trimeric subunit vaccine candidate f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62bab56ab138d615fe9313d074e3b14f
https://doaj.org/article/61db57e69d5a405e82b86f6070a7345d
https://doaj.org/article/61db57e69d5a405e82b86f6070a7345d
Autor:
Danmei Su, Xinglin Li, Xueqin Huang, Cui He, Cheng Zeng, Qiang Wang, Wenchang Qin, Zhongquan Mu, Donna Ambrosino, George Siber, Ralf Clemens, Joshua G. Liang, Peng Liang, Nick Jackson, Rong Xu
The Omicron variant of SARS-COV-2 (GISAID GRA clade [B.1.1.529, BA.1 and BA.2]) is now the single dominant Variant of Concern (VOC). The high number of mutations in the Omicron Spike (S) protein promotes humoral immunological escape. Although a third
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03b37d0842cfd9a109a5f71d0c3c5a77
https://doi.org/10.1101/2022.05.03.490428
https://doi.org/10.1101/2022.05.03.490428
Autor:
Dan Luo, Caixia Wen, Rongchuan Zhao, Xinyu Liu, Xinxin Liu, Jingjing Cui, Joshua G Liang, Peng Liang
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0156106 (2016)
Adenylate kinase (AK) from Escherichia coli was used as both solubility and affinity tag for recombinant protein production. When fused to the N-terminus of a target protein, an AK fusion protein could be expressed in soluble form and purified to nea
Externí odkaz:
https://doaj.org/article/a5e60fb2ff014ad9a2cf1afe35953545
Autor:
Meilin Chen, Mei Luo, Peng Liang, Cui He, Wenchang Qin, Rong Xu, Donna Ambrosino, Xinglin Li, Qiang Wang, George Siber, David M Salisbury, Joshua G. Liang, Ying Liang, Dongxia Luo, Danmei Su, Yilan Zeng, Peiwen Luo, Xiaofang Yang, Xueqin Huang, Ralf Clemens, Jinhua Wu
Beginning in late 2020, the emergence and spread of multiple variant SARS-CoV-2 strains harboring mutations which may enable immune escape necessitates the rapid evaluation of second generation COVID-19 vaccines, with the goal of inducing optimized i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c41ca75b22a079252ae8a18c07449846
https://doi.org/10.1101/2021.05.16.444369
https://doi.org/10.1101/2021.05.16.444369
Autor:
Hong Zhou, Xiaojun Liu, Anliang Huang, Lingmo Chang, Yang Xu, Xinyu Liu, Joshua G. Liang, Peng Liang
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-1 (2018)
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9826798707e35a9476deefd0e131d576
https://doi.org/10.1038/s41598-018-24986-9
https://doi.org/10.1038/s41598-018-24986-9
Autor:
Danmei Su, Qin Song, Xiaodong Wang, Shuaishuai Ge, Peng Liang, Gordon C. Shore, Youwei Li, Michel Gravel, Wei Xu, Haipeng Liu, Jie Zhang, Joshua G. Liang, Anne Roulston, Fei Wang
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-1 (2018)
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::041a6bfd4aa5897d08f9339b60cdbdd8
https://doi.org/10.1038/s41598-018-23057-3
https://doi.org/10.1038/s41598-018-23057-3