Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Joshua F. Heiber"'
Publikováno v:
Haematologica, Vol 100, Iss 3 (2015)
Current therapies for acute myeloid leukemia are associated with high failure and relapse rates. Adoptive immunotherapies, which have shown promise in the treatment of hematologic malignancies, have the potential to target acute myeloid leukemia thro
Externí odkaz:
https://doaj.org/article/8d5c69e2b43049f1a592f3248fec77da
Publikováno v:
Haematologica. 100:336-344
Current therapies for acute myeloid leukemia are associated with high failure and relapse rates. Adoptive immunotherapies, which have shown promise in the treatment of hematologic malignancies, have the potential to target acute myeloid leukemia thro
Autor:
Rae Myers, Mark J. Federspiel, Glen N. Barber, Jaime R. Merchan, Vittal Kurisetty, Guilherme S. Pereira, Jarrard Goodwin, Kah Whye Peng, Joshua F. Heiber, Stephen J. Russell
Publikováno v:
Head & Neck. 36:1619-1627
Background Recombinant vesicular stomatitis virus expressing interferon-β (VSV-IFN-β) has demonstrated antitumor activity in vitro and in vivo. In preparation for clinical testing in human squamous cell carcinoma (SCC) of the head and neck, we cond
Publikováno v:
Chinese Journal of Cancer
In the last decade, we have gained significant understanding of the mechanism by which vesicular stomatitis virus (VSV) specifically kills cancer cells. Dysregulation of translation and defective innate immunity are both thought to contribute to VSV
Autor:
Toni M. Yeasky, Ying Wang, Xiang Xi Xu, Glen N. Barber, Joshua F. Heiber, Callinice D. Capo-chichi
Publikováno v:
Gynecologic Oncology. 116:269-275
Current treatment options for epithelial ovarian cancer are limited and therapeutic development for recurrent and drug-resistant ovarian cancer is an urgent agenda. We investigated the potential use of genetically engineered Vesicular Stomatitis Viru
Autor:
Terrence L. Geiger, Joshua F. Heiber
Publikováno v:
Cellular immunology. 279(1)
Circulating Foxp3(+) regulatory T cells (Treg) may arise in the thymus (natural Treg, nTreg) or through the adaptive upregulation of Foxp3 after T cell activation (induced Treg, iTreg). In this brief review, we explore evidence for the formation and
Autor:
Joshua F, Heiber, Glen N, Barber
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 797
Oncolytic viruses, the use of viruses to treat cancer, is emerging as a new option for cancer therapy. Oncolytic viruses, of both DNA and RNA origin, exhibit the ability to preferentially replicate in and kill cancer cells plausibly due to defects in
Autor:
Joshua F. Heiber, Glen N. Barber
Publikováno v:
Methods in Molecular Biology ISBN: 9781617793394
Oncolytic viruses, the use of viruses to treat cancer, is emerging as a new option for cancer therapy. Oncolytic viruses, of both DNA and RNA origin, exhibit the ability to preferentially replicate in and kill cancer cells plausibly due to defects in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99f7e78832bfcb71114147d16960a94e
https://doi.org/10.1007/978-1-61779-340-0_15
https://doi.org/10.1007/978-1-61779-340-0_15
Autor:
Joshua F. Heiber, Glen N. Barber
Publikováno v:
Journal of virology. 85(20)
Vesicular stomatitis virus (VSV), a negative-strand RNA rhabdovirus, preferentially replicates in and eradicates transformed versus nontransformed cells and is thus being considered for use as a potential anticancer treatment. The genetic malleabilit
Autor:
Peter J. Reid, Rachel Elsby, Graham D. Pavitt, Joshua F. Heiber, Scot R. Kimball, Glen N. Barber
Publikováno v:
Journal of virology. 85(19)
Eukaryotic translation initiation factor 2B (eIF2B) is a heteropentameric guanine nucleotide exchange factor that converts protein synthesis initiation factor 2 (eIF2) from a GDP-bound form to the active eIF2-GTP complex. Cellular stress can repress