Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Joshua E. Lehrer-Graiwer"'
Autor:
Megan H. MacNabb, Matthias Nahrendorf, James K. Min, Khurram Nasir, Ahmed Tawakol, Amparo L. Figueroa, Zahi A. Fayad, James H.F. Rudd, Hamed Emami, Magnus Korsgren, Udo Hoffmann, Zachary R Lavender, Amos Baruch, Barry B. Rubin, Quynh A. Truong, Jill Fredrickson, Esad Vucic, Joshua E. Lehrer-Graiwer, Parmanand Singh
Publikováno v:
JACC: Cardiovascular Imaging. 8(2):121-130
Objectives This study sought to determine whether splenic activation after acute coronary syndrome (ACS) is linked to leukocyte proinflammatory remodeling and whether splenic activity independently predicts the risk of cardiovascular disease (CVD) ev
Autor:
Nuno Arantes-Oliveira, Andrew G. Fraser, Ao Lin Hsu, Julie Ahringer, Joshua E. Lehrer-Graiwer, Ravi S. Kamath, Honor Hsin, Andrew Dillin, Cynthia Kenyon
Publikováno v:
Science. 298:2398-2401
To explore the role of mitochondrial activity in the aging process, we have lowered the activity of the electron transport chain and adenosine 5′-triphosphate (ATP) synthase with RNA interference (RNAi) in Caenorhabditis elegans. These perturbation
Autor:
Sarah E. Craven, Alaa El-Husseini, Chiye Aoki, Joshua E. Lehrer-Graiwer, J. Rick Topinka, Bonnie L. Firestein, David S. Bredt
Publikováno v:
Journal of Biological Chemistry. 275:23904-23910
The postsynaptic density protein PSD-95 and related membrane-associated guanylate kinase (MAGUK) proteins assemble signal transduction complexes at sites of cell-cell contact including synapses. Whereas PSD-95 and PSD-93 occur only at postsynaptic si
Publikováno v:
Neuroscience Letters. 288:107-110
Neurons that express neuronal nitric oxide synthase (nNOS) are selectively spared from nitric oxide (NO)-induced cytotoxicity in acute cerebral ischemia and neurodegenerative conditions but the mechanism of this resistance is unknown. To identify spe
Publikováno v:
Current Atherosclerosis Reports. 15
In this article, CSL112, an HDL-infusion therapy in clinical development has been incorrectly described as a synthetic reconstituted HDL mimetic currently in a Phase 2 IVUS plaque regression study. Correction : CSL112 is a novel formulation of apoA-I
Publikováno v:
Current atherosclerosis reports. 15(6)
Despite dramatic advances in standard of care, the risk of recurrent myocardial infarction early after an acute coronary syndrome (ACS) remains high. This period of elevated risk after a cardiovascular event is associated with an acute inflammatory r
Autor:
Zahi A. Fayad, Amr Abdelbaky, Jill Fredrickson, Parmanand Singh, Brian B. Ghoshhajra, Magnus Korsgren, Michael Koren, Daniel Duprez, Eli M. Roth, Amos Baruch, Christie M. Ballantyne, Nick Van Bruggen, Esad Vucic, Joshua E. Lehrer-Graiwer, Frank Hsieh, Ahmed Tawakol, Robert S. Rosenson, James H.F. Rudd, Meina T. Tang, Björn Frendéus
Publikováno v:
JACC: Cardiovascular Imaging. (4):493-494
Previous reports have demonstrated that oxidized low-density lipoprotein (oxLDL) is a key mediator in atherogenesis [(1)][1]. oxLDL increases endothelial cell adhesion molecules, recruitment of inflammatory cells into the vessel wall, and formation o