Zobrazeno 1 - 10
of 15 809
pro vyhledávání: '"Joshua E"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract The C-terminal domain of RPB1 (CTD) orchestrates transcription by recruiting regulators to RNA Pol II upon phosphorylation. With CTD driving condensate formation on gene loci, the molecular mechanism behind how CTD-mediated recruitment of tr
Externí odkaz:
https://doaj.org/article/5617c07b006f4dc7b2e870a33e0063c5
Autor:
Kun Leng, Brendan Rooney, Frank McCarthy, Wenlong Xia, Indigo V. L. Rose, Sophie Bax, Marcus Chin, Saeed Fathi, Kari A. Herrington, Manuel Leonetti, Aimee Kao, Stephen P. J. Fancy, Joshua E. Elias, Martin Kampmann
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Astrocytes respond and contribute to neuroinflammation by adopting inflammatory reactive states. Although recent efforts have characterized the gene expression signatures associated with these reactive states, the cell biology underlying inf
Externí odkaz:
https://doaj.org/article/3362c7cd0c774b99bc1e41cc97a52ae6
Autor:
Joshua E Allen, Gabriel Krigsfeld, Luv Patel, Patrick A Mayes, David T Dicker, Gen Sheng Wu, Wafik S El-Deiry
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/fc6b85f6734f493ba36e3a76e182456c
Autor:
Jeneen Hadj-Hammou, Joshua E. Cinner, Diego R. Barneche, Iain R. Caldwell, David Mouillot, James P. W. Robinson, Nina M. D. Schiettekatte, Alexandre C. Siqueira, Brett M. Taylor, Nicholas A. J. Graham
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Fish fecundity scales hyperallometrically with body mass, meaning larger females produce disproportionately more eggs than smaller ones. We explore this relationship beyond the species-level to estimate the “reproductive potential” of 16
Externí odkaz:
https://doaj.org/article/13e525f6826f4e39b67e75e0e6ed688f
Autor:
Jesse Hill, MD, MSc, Esther H. Yang, BSc, MSc, Dennis Lefebvre, MD, PhD, Shandra Doran, MD, PhD, Sean van Diepen, MD, FRCPC, Joshua E. Raizman, PhD, Albert K.Y. Tsui, PhD, Brian H. Rowe, MD, MSc
Publikováno v:
CJC Open, Vol 6, Iss 7, Pp 915-924 (2024)
Background: This study strove to assess the impact of the implementation of an accelerated diagnostic protocol (ADP), using shortened serial-testing intervals and a conventional troponin I (c-TnI) test, on emergency department (ED) length of stay (LO
Externí odkaz:
https://doaj.org/article/86452b5b65e64420932b3a2e75901230
Autor:
Djibril M. Ba, Chrispin Kayembe, Joe Littlejohn, Lauren J. Van Scoy, Erika VanDyke, James Williams, Avnish Katoch, Neil C. Shook, Yue Zhang, Craig Livelsberger, Alicia C. McDonald, Joshua E. Muscat
Publikováno v:
Current Oncology, Vol 31, Iss 7, Pp 3698-3712 (2024)
The rapid increase in telehealth has the potential to bring informed decision-making for prostate cancer screening (PCS) at the population level to high-risk individuals. We utilized a global technology platform of electronic health records data repo
Externí odkaz:
https://doaj.org/article/9a1bfdad0d2d43f49a3a51477716020c
Autor:
Tess D. Pottinger, Joshua E. Motelow, Gundula Povysil, Cristiane A. Martins Moreno, Zhong Ren, Hemali Phatnani, The New York Genome Center ALS Sequencing Consortium, Timothy J. Aitman, Javier Santoyo-Lopez, Scottish Genomes Partnership, Hiroshi Mitsumoto, ALS COSMOS Study Group, PLS COSMOS Study Group, GTAC Investigators, David B. Goldstein, Matthew B. Harms
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Background Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease affecting over 300,000 people worldwide. It is characterized by the progressive decline of the nervous system that leads to the weakening of muscles which impacts
Externí odkaz:
https://doaj.org/article/77b804dfb5a346ffb655ea53c881d520
Autor:
Xinyue Wang, Liming Li, Xun Jiang, Patrick M. Fry, Robert A. West, Conor A. Nixon, Larry Guan, Thishan D. Karandana G, Ronald Albright, Joshua E. Colwell, Tristan Guillot, Mark D. Hofstadter, Matthew E. Kenyon, Anthony Mallama, Santiago Perez-Hoyos, Agustin Sanchez-Lavega, Amy A. Simon, Daniel Wenkert, Xi Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract The global energy budget is pivotal to understanding planetary evolution and climate behaviors. Assessing the energy budget of giant planets, particularly those with large seasonal cycles, however, remains a challenge without long-term obser
Externí odkaz:
https://doaj.org/article/08f31c7e99aa4aca823c6701b3661877
Autor:
Simon Gilbody, Dean McMillan, Bob Phillips, Kym I E Snell, Richard D Riley, David A Richards, Jaime Delgadillo, Shehzad Ali, Chris Salisbury, Lewis W Paton, Lucinda Archer, Peter A Coventry, Stephen Pilling, Andrew S Moriarty, Joshua E J Buckman, Nick Meader, Carolyn A Chew Graham
Publikováno v:
BMJ Mental Health, Vol 27, Iss 1 (2024)
Background Relapse of depression is common and contributes to the overall associated morbidity and burden. We lack evidence-based tools to estimate an individual’s risk of relapse after treatment in primary care, which may help us more effectively
Externí odkaz:
https://doaj.org/article/c4859bb2eb6f4002ae87fcb089d753f9
Autor:
Stefan Dascalu, Joshua E. Sealy, Jean-Remy Sadeyen, Patrik G. Flammer, Steven Fiddaman, Stephen G. Preston, Robert J. Dixon, Michael B. Bonsall, Adrian L. Smith, Munir Iqbal
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Avian influenza viruses (AIVs) are a major economic burden to the poultry industry and pose serious zoonotic risks, with human infections being reported every year. To date, the vaccination of birds remains the most important method for the preventio
Externí odkaz:
https://doaj.org/article/5d220b690bd942aaac8d57e61f935630