Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Joshua D. Horvath"'
Publikováno v:
Fluids and Barriers of the CNS, Vol 21, Iss 1, Pp 1-14 (2024)
Abstract Background Achieving effective drug delivery to the central nervous system (CNS) remains a challenge for treating neurological disorders. Intrathecal (IT) delivery, which involves direct injection into the cerebrospinal fluid (CSF), presents
Externí odkaz:
https://doaj.org/article/948e62293a1542d4acb79495b0302fd9
Autor:
Akari Seiner, Goutham Kumar Reddy Burla, Dev Shrestha, Mayumi Bowen, Joshua D. Horvath, Bryn A. Martin
Publikováno v:
Frontiers in Neuroimaging. 1
BackgroundUnderstanding the relationship between cerebrospinal fluid (CSF) dynamics and intrathecal drug delivery (ITDD) injection parameters is essential to improve treatment of central nervous system (CNS) disorders.MethodsAn anatomically detailed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd3fe7af5b5904d9b539cb343f18935c
https://doi.org/10.3389/fnimg.2022.879098
https://doi.org/10.3389/fnimg.2022.879098
Autor:
Robert F. Kelley, Devin B. Tesar, Yue Wang, Nicholas J. Agard, Patrick G. Holder, Joyce Chan, Laetitia Comps-Agrar, Judit Horvath, Joshua D. Horvath, Susan R. Crowell
Publikováno v:
Molecular pharmaceutics. 19(5)
Treatment of age-related macular degeneration (AMD) with anti-vascular endothelial growth factor (VEGF) biologic agents has been shown to restore and maintain visual acuity for many patients afflicted with wet AMD. These agents are usually administer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6095b527f1e688da14152e395c7c08a3
https://pubmed.ncbi.nlm.nih.gov/35393854
https://pubmed.ncbi.nlm.nih.gov/35393854
Publikováno v:
Journal of physics. Condensed matter : an Institute of Physics journal. 29(3)
The desorption kinetics of a chiral compound, R-3-methylcyclohexanone (R-3MCHO), have been measured on both enantiomers of seven chiral Cu(hkl)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e105692b1c4cb54b330b0ee7fbcced4c
https://pubmed.ncbi.nlm.nih.gov/27845932
https://pubmed.ncbi.nlm.nih.gov/27845932
Publikováno v:
The Journal of Physical Chemistry C. 112:7637-7643
The high Miller index planes of metal single crystals are chiral, if they do not lie perpendicular to any of the mirror symmetry planes of the bulk lattice. Such chiral surfaces of face-centered cubic metals expose kinked step edges and have been sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bde0a4a0fdc580faf397636aca9ead6
https://doi.org/10.1021/jp0753878
https://doi.org/10.1021/jp0753878
Publikováno v:
Journal of the American Chemical Society. 126:14988-14994
Kinked-stepped, high Miller index surfaces of metal crystals are chiral and, therefore, exhibit enantiospecific properties. Previous temperature-programmed desorption (TPD) spectra have shown that the desorption energies of R-3-methylcyclohexanone (R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46da012a0b6e778ee10d8e6a444cdee4
https://doi.org/10.1021/ja045537h
https://doi.org/10.1021/ja045537h
Publikováno v:
Surface Science. 563:217-224
Scanning tunneling microscopy (STM) and temperature programmed desorption (TPD) measurements have revealed that the straight step edges of Cu(5 3 3) surfaces are reconstructed by the room temperature adsorption of R-3methylcyclohexanone (R-3-MCHO). S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39d171e95d5c2cef84cd464fa4ccd895
https://doi.org/10.1016/j.susc.2004.06.159
https://doi.org/10.1016/j.susc.2004.06.159
Publikováno v:
Surface Science. 563:206-216
Density functional theory (DFT) and temperature programmed desorption (TPD) experiments have been used to probe the site preferences of adsorbed iodine atoms on Cu surfaces. DFT calculations are presented for iodine adsorption on Cu(1 1 1), Cu(1 0 0)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2a3c328c1bcf4b72abb0cb6d4908a45
https://doi.org/10.1016/j.susc.2004.06.160
https://doi.org/10.1016/j.susc.2004.06.160
Autor:
Andrew J. Gellman, Joshua D. Horvath
Publikováno v:
Journal of the American Chemical Society. 124:2384-2392
Temperature-programmed desorption (TPD) experiments have been conducted to investigate enantiospecific desorption from chiral single-crystal surfaces. The (643) and (six four three) planes of face-centered cubic metals such as Cu have kinked and step
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9def1b70f66bedcdfbe1e27d8d9c1549
https://doi.org/10.1021/ja012182i
https://doi.org/10.1021/ja012182i
Publikováno v:
Journal of Molecular Catalysis A: Chemical. 167:3-11
Several experiments have been performed to probe the enantiospecific properties of chiral single crystal surfaces. The surfaces chosen have been the (643) planes of Ag and Cu, both face centered cubic structures. The chirality of these surfaces arise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6969b3e75061740a713cfe56ee728d59
https://doi.org/10.1016/s1381-1169(00)00484-2
https://doi.org/10.1016/s1381-1169(00)00484-2