Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Joshua D Strauss"'
Publikováno v:
IUCrJ, Vol 9, Iss 2, Pp 243-252 (2022)
Limitations to successful single-particle cryo-electron microscopy (cryo-EM) projects include stable sample generation, production of quality cryo-EM grids with randomly oriented particles embedded in thin vitreous ice and access to microscope time.
Externí odkaz:
https://doaj.org/article/9a3eba09b8f448d5b745000824830b97
Autor:
Luba A. Aleksandrov, Adrei A. Aleksandrov, Timothy J. Jensen, Joshua D. Strauss, Jonathan F. Fay
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 16, p 9248 (2022)
Cystic fibrosis transmembrane regulator (CFTR) is a dynamic membrane protein belonging to the ABC transporter family. It is unusual within this family as it is an ion channel, as opposed to a transporter. Activation of CFTR requires ATP and phosphory
Externí odkaz:
https://doaj.org/article/3cec2d9334a344478dfa5fe9e56fa11e
Autor:
Zunlong Ke, Joshua D. Strauss, Cheri M. Hampton, Melinda A. Brindley, Rebecca S. Dillard, Fredrick Leon, Kristen M. Lamb, Richard K. Plemper, Elizabeth R. Wright
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Virus assembly is technically challenging to study. Here the authors use cryo-electron tomography of measles virus-infected human cells to determine native-state virus structure and they locate well-ordered M lattices that organize viral glycoprotein
Externí odkaz:
https://doaj.org/article/8cf6586c2905457c8522577aa118213b
Autor:
Christopher C. Stobart, Christina A. Rostad, Zunlong Ke, Rebecca S. Dillard, Cheri M. Hampton, Joshua D. Strauss, Hong Yi, Anne L. Hotard, Jia Meng, Raymond J. Pickles, Kaori Sakamoto, Sujin Lee, Michael G. Currier, Syed M. Moin, Barney S. Graham, Marina S. Boukhvalova, Brian E. Gilbert, Jorge C. G. Blanco, Pedro A. Piedra, Elizabeth R. Wright, Martin L. Moore
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Development of a safe and efficacious vaccine for respiratory syncytial virus (RSV) has been challenging. Here the authors generate a live-attenuated RSV vaccine that shows increased thermostability and immunogenicity, and protects cotton rats from R
Externí odkaz:
https://doaj.org/article/2a61be93aec04ad3a0b22213856c0d55
Autor:
Gabrielle R Budziszewski, Yani Zhao, Cathy J Spangler, Katarzyna M Kedziora, Michael R Williams, Dalal N Azzam, Aleksandra Skrajna, Yuka Koyama, Andrew P Cesmat, Holly C Simmons, Eyla C Arteaga, Joshua D Strauss, Dmitri Kireev, Robert K McGinty
Publikováno v:
Nucleic Acids Research. 50:4355-4371
A key role of chromatin kinases is to phosphorylate histone tails during mitosis to spatiotemporally regulate cell division. Vaccinia-related kinase 1 (VRK1) is a serine–threonine kinase that phosphorylates histone H3 threonine 3 (H3T3) along with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b4fc712a694ff79d54241e2704864b6
https://doi.org/10.1093/nar/gkac198
https://doi.org/10.1093/nar/gkac198
Publikováno v:
Microscopy and Microanalysis. 28:1288-1290
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5714ea76fe3050c22ca919de0e7a1e8
https://doi.org/10.1017/s1431927622005293
https://doi.org/10.1017/s1431927622005293
Publikováno v:
Microscopy and Microanalysis. 27:832-834
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24c624c316d044b0b86b319fe2db5764
https://doi.org/10.1017/s1431927621003275
https://doi.org/10.1017/s1431927621003275
Autor:
Andrew P. Cesmat, Robert K. McGinty, Qi Zhang, Cathy J. Spangler, Joshua D. Strauss, Pengda Liu, Joshua A. Boyer
Publikováno v:
Science
Saving a host cell from itself A fundamental mammalian defense mechanism against pathogens and damaged cellular DNA is to recognize DNA fragments in the cytosol and trigger an inflammatory response. The cyclic guanosine monophosphate–adenosine mono
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b04a141b630f7cdc72ca49af2639e5
https://doi.org/10.1126/science.abd0609
https://doi.org/10.1126/science.abd0609
Autor:
Zunlong Ke, Rebecca S. Dillard, Tatiana Chirkova, Fredrick Leon, Christopher C. Stobart, Cheri M. Hampton, Joshua D. Strauss, Devi Rajan, Christina A. Rostad, Jeannette V. Taylor, Hong Yi, Raven Shah, Mengtian Jin, Tina V. Hartert, R. Stokes Peebles, Barney S. Graham, Martin L. Moore, Larry J. Anderson, Elizabeth R. Wright
Publikováno v:
Viruses, Vol 10, Iss 8, p 446 (2018)
Human respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract disease in young children. With repeat infections throughout life, it can also cause substantial disease in the elderly and in adults with compromised cardiac, pu
Externí odkaz:
https://doaj.org/article/b83229ea519e4e5e93301f5ad75312af
Autor:
Duhyeong Hwang, Marina Sokolsky-Papkov, Alexander V. Kabanov, Jacob D. Ramsey, Chaemin Lim, Joshua D. Strauss, Susana C. M. Teixeira, Chi-Duen Poon
Significant advances in physicochemical properties of polymeric micelles enable optimization of therapeutic drug efficacy, supporting nanomedicine manufacturing and clinical translation. Yet, the effect of micelle morphology on pharmacological effica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd0475f46403ead3f732e5b138944345
https://doi.org/10.1101/2021.06.10.447962
https://doi.org/10.1101/2021.06.10.447962
