Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Joshua D Berkowitz"'
Autor:
Bruce S. Burnham, John T. Gupton, Keith Krumpe, John R. Lukens, Robert B. Miller, Joshua D. Berkowitz, Bryan J. McCranor, Kam Suet Lam, Josephine Glersaye, Ulander Miott, Brett M. Taylor, Donna L. Wilson, Shahzad Rifat, Gerard A. Dalglish, Daniel C. Smith, Michael A. Evans, Anthony Argenti, Adam Getzel, Kathy O'Toole-Colin, Justin M. Holub
Publikováno v:
Molecules, Vol 9, Iss 3, Pp 134-157 (2004)
A series of substituted 2-phenacyl-3-phenyl-1H-pyrrole-4-carboxylates were prepared from substituted acetophenones in 6 steps. The final condensations between a chloroenal and an aminoketone were carried out under neutral conditions in parallel to yi
Externí odkaz:
https://doaj.org/article/e22d8e87294f4356a67eed35a8b783b0
Autor:
Mardel Cooper, Charles E. Carraher, Joshua D. Berkowitz, Larisa Gofman, Kenzo Morie, Lisa-Marie Bergh, Bruce S. Burnham, Jodi Hallback, Bryan J. McCranor, Kurt McCann, Justin M. Holub, Melissa Melendez, Kyle Pillitteri, Zachary Orr
Publikováno v:
Letters in Drug Design & Discovery. 8:544-549
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9498e5d3b2ad2c1666b06cb02fbfcae
https://doi.org/10.2174/157018011795906839
https://doi.org/10.2174/157018011795906839
Autor:
Daniel C. Smith, Keith Krumpe, Richard W. Durham, Anthony Argenti, Michael A. Evans, Joshua D. Berkowitz, Tanya C. Scarlett, Mafoloe Hoff, Gerard A. Dalglish, Bruce S. Burnham, Donna L. Wilson, Justin M. Holub, Iris H. Hall, John T. Gupton, Brett M. Taylor
Publikováno v:
Archiv der Pharmazie. 336:181-190
The substituted ethyl-2-phenacyl-3-phenylpyrrole-4-carboxylates were synthesized by a condensation of a beta-chloroenal and an alpha-aminoketone under neutral conditions. They proved to be potent cytotoxic agents against the growth of murine L1210 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::095cee982ffbaba66348796f7c290a12
https://doi.org/10.1002/ardp.200390018
https://doi.org/10.1002/ardp.200390018
Autor:
Joshua D. Berkowitz, Richard W. Durham, Richard J. Crosswicks, Bruce S. Burnham, Tanya C. Scarlett, Iris H. Hall
Publikováno v:
Metal-Based Drugs
N6-Benzoyladenine-cyanoborane (2), and 6-triphenylphosphonylpurine-cyanoborane (3) were selected for investigation of cytotoxicity in murine and human tumor cell lines, effects on human HL-60 leukemic metabolism and DNA strand scission to determine t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f45b4de6c1a0bef0428d8f35b15bc65
https://doi.org/10.1155/mbd.2002.19
https://doi.org/10.1155/mbd.2002.19
Autor:
Joshua D Berkowitz, Boyd L. Harrison, Robert Martone, Hua Zhou, Micheal Chlenov, Yun Hu, Peimin Lu, Koi Michele Morris, June Sonnenberg-Reines, S. Aschmies, Joan E. Sabalski, Kerri Lipinski, George Diamantidis, Kevin Atchison, Thomas J. Caggiano, Shaiu-Ching Sun, Zheng Xu, Jun Pu, Anthony F. Kreft, Dave R. Riddell, Yiqun Wang, Lynn Resnick, Mei Jin, Donna M. Huryn, Erik Wagner, J. Steven Jacobsen
Publikováno v:
Bioorganicmedicinal chemistry. 17(13)
gamma-Secretase inhibitors have been shown to reduce the production of beta-amyloid, a component of the plaques that are found in brains of patients with Alzheimer's disease. A novel series of heterocyclic sulfonamide gamma-secretase inhibitors that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccb35335c5e137415c463df8839ade10
https://pubmed.ncbi.nlm.nih.gov/19443228
https://pubmed.ncbi.nlm.nih.gov/19443228
Autor:
Justin M. Holub, Kam Suet Lam, Daniel C. Smith, Donna L. Wilson, Robert B. Miller, Joshua D. Berkowitz, Anthony Argenti, John R. Lukens, Bryan J. McCranor, Michael A. Evans, Shahzad Rifat, Gerard A. Dalglish, Adam Getzel, Brett M. Taylor, John T. Gupton, Bruce S. Burnham, Josephine Glersaye, Ulander Miott, Kathy O'Toole-Colin, Keith Krumpe
Publikováno v:
Molecules, Vol 9, Iss 3, Pp 134-157 (2004)
Molecules; Volume 9; Issue 3; Pages: 134-157
Molecules; Volume 9; Issue 3; Pages: 134-157
A series of substituted 2-phenacyl-3-phenyl-1H-pyrrole-4-carboxylates were prepared from substituted acetophenones in 6 steps. The final condensations between a chloroenal and an aminoketone were carried out under neutral conditions in parallel to yi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33a68a8bc3a48bc53055dd38836ad941
https://europepmc.org/articles/PMC6147299/
https://europepmc.org/articles/PMC6147299/
Autor:
Michael A. Evans, Daniel C. Smith, Justin M. Holub, Anthony Argenti, Mafoloe Hoff, Gerard A. Dalglish, Donna L. Wilson, Brett M. Taylor, Joshua D. Berkowitz, Bruce S. Burnham, Keith Krumpe, John T. Gupton, Tanya C. Scarlett, Richard W. Durham Jr, Iris H. Hall
Publikováno v:
Archiv der Pharmazie; Jun2003, Vol. 336 Issue 3, p181-190, 10p