Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Joshua D, Podlevsky"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract CRISPR arrays and CRISPR-associated (Cas) proteins comprise a prevalent adaptive immune system in bacteria and archaea. These systems defend against exogenous parasitic mobile genetic elements. The adaption of single effector CRISPR-Cas syst
Externí odkaz:
https://doaj.org/article/f34e83c9f6844f03aea7ae8e91457eea
Autor:
Kimberly S. Butler, Bryan D. Carson, Joshua D. Podlevsky, Cathryn M. Mayes, Jessica M. Rowland, DeAnna Campbell, J. Bryce Ricken, George Wudiri, The SNL COVID Dx Assay Team, Jerilyn A. Timlin
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract For workplaces which cannot operate as telework or remotely, there is a critical need for routine occupational SARS-CoV-2 diagnostic testing. Although diagnostic tests including the CDC 2019-Novel Coronavirus (2019-nCoV) Real-Time RT-PCR Dia
Externí odkaz:
https://doaj.org/article/f238737a0b1343228df91a681d5e85e8
Autor:
Dhenugen Logeswaran, Yang Li, Khadiza Akhter, Joshua D. Podlevsky, Tamara L. Olson, Katherine Forsberg, Julian J.-L. Chen
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Telomerase is a eukaryotic ribonucleoprotein (RNP) enzyme that adds DNA repeats onto chromosome ends to maintain genomic stability and confer cellular immortality in cancer and stem cells. The telomerase RNA (TER) component is essential for telomeras
Autor:
Flávia S Donaires, Natália F Scatena, Raquel M Alves-Paiva, Joshua D Podlevsky, Dhenugen Logeswaran, Barbara A Santana, Andreza C Teixeira, Julian J-L Chen, Rodrigo T Calado, Ana L C Martinelli
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183287 (2017)
Telomeres are repetitive DNA sequences at linear chromosome termini, protecting chromosomes against end-to-end fusion and damage, providing chromosomal stability. Telomeres shorten with mitotic cellular division, but are maintained in cells with high
Externí odkaz:
https://doaj.org/article/eff92107e14f4c0bad8391e108f36032
Publikováno v:
Molecular Biology and Evolution
Telomerase RNA (TR) is a noncoding RNA essential for the function of telomerase ribonucleoprotein. TRs from vertebrates, fungi, ciliates, and plants exhibit extreme diversity in size, sequence, secondary structure, and biogenesis pathway. However, th
Autor:
Jennie H, Appel, Duo O, Li, Joshua D, Podlevsky, Abhishek, Debnath, Alexander A, Green, Qing Hua, Wang, Junseok, Chae
Publikováno v:
ACS biomaterials scienceengineering. 2(3)
Atomically thin transition-metal dichalcogenides (TMDs) have attracted considerable interest because of their unique combination of properties, including photoluminescence, high lubricity, flexibility, and catalytic activity. These unique properties
Publikováno v:
NAR Genomics and Bioinformatics
CRISPR arrays and CRISPR-associated (Cas) proteins comprise a widespread adaptive immune system in bacteria and archaea. These systems function as a defense against exogenous parasitic mobile genetic elements that include bacteriophages, plasmids and
Autor:
Jason C. Harper, Edwin A. Saada, Joshua D. Podlevsky, Steven S. Branda, Robert K. Johnston, Jerilyn A. Timlin, Kyle J. Seamon
Publikováno v:
Biosensorsbioelectronics. 141
The clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) ribonucleoprotein (RNP) complex is an RNA-guided DNA-nuclease that is part of the bacterial adaptive immune system. CRISPR/Cas9 RNP has been ada