Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Joshua D, Garcia"'
Autor:
Joshua D. Garcia, Sarah E. Wolfe, Amber R. Stewart, Erika Tiemeier, Sara E. Gookin, Mayra Bueno Guerrero, Nidia Quillinan, Katharine R. Smith
Publikováno v:
iScience, Vol 26, Iss 10, Pp 108061- (2023)
Summary: Synaptic inhibition is critical for controlling neuronal excitability and function. During global cerebral ischemia (GCI), inhibitory synapses are rapidly eliminated, causing hyper-excitability which contributes to cell-death and the pathoph
Externí odkaz:
https://doaj.org/article/edb341abaf2f4e43b5873403d0258911
Autor:
E Mae Guthman, Joshua D Garcia, Ming Ma, Philip Chu, Serapio M Baca, Katharine R Smith, Diego Restrepo, Molly M Huntsman
Publikováno v:
eLife, Vol 9 (2020)
The basolateral amygdala (BLA) plays a vital role in associating sensory stimuli with salient valence information. Excitatory principal neurons (PNs) undergo plastic changes to encode this association; however, local BLA inhibitory interneurons (INs)
Externí odkaz:
https://doaj.org/article/1935d86d414344138ff9d6dc3c140a8b
Autor:
Kevin C. Crosby, Sara E. Gookin, Joshua D. Garcia, Katlin M. Hahm, Mark L. Dell’Acqua, Katharine R. Smith
Publikováno v:
Cell Reports, Vol 26, Iss 12, Pp 3284-3297.e3 (2019)
Summary: Inhibitory synapses mediate the majority of synaptic inhibition in the brain, thereby controlling neuronal excitability, firing, and plasticity. Although essential for neuronal function, the central question of how these synapses are organiz
Externí odkaz:
https://doaj.org/article/177e5de8518b4b4f9459c49e82a08221
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114235 (2014)
Communication between cortical cell polarity cues and the mitotic spindle ensures proper orientation of cell divisions within complex tissues. Defects in mitotic spindle positioning have been linked to various developmental disorders and have recentl
Externí odkaz:
https://doaj.org/article/1f17b5247d7a49fbb60588de5aad267d
Autor:
Molly M. Huntsman, Philip Chu, Serapio M. Baca, E Mae Guthman, Ming Ma, Joshua D. Garcia, Diego Restrepo, Katharine R. Smith
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
The basolateral amygdala (BLA) plays a vital role in associating sensory stimuli with salient valence information. Excitatory principal neurons (PNs) undergo plastic changes to encode this association; however, local BLA inhibitory interneurons (INs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b7a8e0209b2d05310ee94d47f81bb78
http://europepmc.org/articles/PMC6984813
http://europepmc.org/articles/PMC6984813
Autor:
Joshua D. Garcia, Sara E. Gookin, Kevin C. Crosby, Samantha L. Schwartz, Erika Tiemeier, Matthew J. Kennedy, Mark L. Dell’Acqua, Paco S. Herson, Nidia Quillinan, Katharine R. Smith
Publikováno v:
Cell Reports. 37:110142
GABAergic synaptic inhibition controls neuronal firing, excitability, and synaptic plasticity to regulate neuronal circuits. Following an acute excitotoxic insult, inhibitory synapses are eliminated, reducing synaptic inhibition, elevating circuit ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e39afed94b9cd61a672264cfb2d1bdb
https://doi.org/10.1016/j.celrep.2021.110142
https://doi.org/10.1016/j.celrep.2021.110142
Autor:
Dipen, Rajgor, Alicia M, Purkey, Jennifer L, Sanderson, Theresa M, Welle, Joshua D, Garcia, Mark L, Dell'Acqua, Katharine R, Smith
Publikováno v:
Cell reports
SUMMARY Molecular mechanisms underlying plasticity at brain inhibitory synapses remain poorly characterized. Increased postsynaptic clustering of GABAA receptors (GABAARs) rapidly strengthens inhibition during inhibitory long-term potentiation (iLTP)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f00e0dfef12a40f26aefd3bbbfe4b211
https://pubmed.ncbi.nlm.nih.gov/32579917
https://pubmed.ncbi.nlm.nih.gov/32579917
Autor:
Mark L. Dell'Acqua, Katharine R. Smith, Katlin M. Hahm, Sara E. Gookin, Joshua D. Garcia, Kevin C. Crosby
Publikováno v:
Cell Reports, Vol 26, Iss 12, Pp 3284-3297.e3 (2019)
Summary: Inhibitory synapses mediate the majority of synaptic inhibition in the brain, thereby controlling neuronal excitability, firing, and plasticity. Although essential for neuronal function, the central question of how these synapses are organiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c4f452113d874befed4ee0af7a1de2f
https://europepmc.org/articles/PMC6529211/
https://europepmc.org/articles/PMC6529211/
Autor:
Joshua D. Garcia, Dipen Rajgor, Jennifer L. Sanderson, Theresa M. Welle, Mark L. Dell'Acqua, Alicia Purkey, Katharine R. Smith
Publikováno v:
Cell Reports. 31:107785
Molecular mechanisms underlying plasticity at brain inhibitory synapses remain poorly characterized. Increased postsynaptic clustering of GABAA receptors (GABAARs) rapidly strengthens inhibition during inhibitory long-term potentiation (iLTP). Howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::816c478b260a7f79b866da42e1806eb9
https://doi.org/10.1016/j.celrep.2020.107785
https://doi.org/10.1016/j.celrep.2020.107785