Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Joshua D'Rozario"'
Autor:
Swee Heng Milon Pang, Joshua D’Rozario, Senora Mendonca, Tejasvini Bhuvan, Natalie L. Payne, Di Zheng, Assifa Hisana, Georgia Wallis, Adele Barugahare, David Powell, Jai Rautela, Nicholas D. Huntington, Grant Dewson, David C. S. Huang, Daniel H. D. Gray, Tracy S. P. Heng
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Mesenchymal stromal cells (MSCs) demonstrate therapeutic benefits in multiple diseases, but the mechanisms remain unclear as infused MSCs do not persist in the body. Here, the authors show that MSC apoptosis is an important mechanistic element, as MS
Externí odkaz:
https://doaj.org/article/301d7cf4f8394cb5843dbd85fe61a7dd
Autor:
Johannes Brägelmann, Carina Lorenz, Sven Borchmann, Kazuya Nishii, Julia Wegner, Lydia Meder, Jenny Ostendorp, David F. Ast, Alena Heimsoeth, Takamasa Nakasuka, Atsuko Hirabae, Sachi Okawa, Marcel A. Dammert, Dennis Plenker, Sebastian Klein, Philipp Lohneis, Jianing Gu, Laura K. Godfrey, Jan Forster, Marija Trajkovic-Arsic, Thomas Zillinger, Mareike Haarmann, Alexander Quaas, Stefanie Lennartz, Marcel Schmiel, Joshua D’Rozario, Emily S. Thomas, Henry Li, Clemens A. Schmitt, Julie George, Roman K. Thomas, Silvia von Karstedt, Gunther Hartmann, Reinhard Büttner, Roland T. Ullrich, Jens T. Siveke, Kadoaki Ohashi, Martin Schlee, Martin L. Sos
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Kinase inhibitors are widely used to treat cancer, however patients frequently develop resistance. Here, the authors investigate adaption mechanisms during drug persistence and show that stimulation of the innate immunity sensor RIG-I enhances cancer
Externí odkaz:
https://doaj.org/article/9def69d01bbd4809814653393e15ac1f
Autor:
Joshua D'Rozario, Konstantin Knoblich, Mechthild Lütge, Christian Pérez Shibayama, Hung‐Wei Cheng, Yannick O. Alexandre, David Roberts, Joana Campos, Emma Dutton, Muath Suliman, Alice E. Denton, Shannon J. Turley, Richard L. Boyd, Scott N. Mueller, Burkhard Ludewig, Tracy S.P. Heng, Anne L. Fletcher
Publikováno v:
European Journal of Immunology.
Publikováno v:
Cancer Research. 82:6028-6028
Small cell lung cancer (SCLC) accounts for approximately 15% of all lung cancers with an overall 5-year survival rate of 5-10%. Although transgenic mouse models and patient derived xenograft models have been shown to capture the heterogeneity and com
Autor:
Joshua D'Rozario, Konstantin Knoblich, Mechthild Luetge, Christian Perez Shibayama, Hung-Wei Cheng, Yannick O. Alexandre, David Roberts, Joana Campos, Jillian Astarita, Emma Dutton, Muath Suliman, Alice E. Denton, Shannon J. Turley, Richard L. Boyd, Scott Mueller, Burkhard Ludewig, Tracy Heng, Anne L. Fletcher
Publikováno v:
SSRN Electronic Journal.
Publikováno v:
Advances in experimental medicine and biology. 1060
Lymph nodes play a crucial role in the formation and initiation of immune responses, allowing lymphocytes to efficiently scan for foreign antigens and serving as rendezvous points for leukocyte-antigen interactions. Here we describe the major stromal
Autor:
JOSHUA D'ROZARIO
Whilst long believed to perform a solely structural role, stromal cells are connective cells within tissues and organs, which have to evolved to play a variety of roles to regulate the immune system. As a result, these cell types have been utilised s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19daa2f50e4865ef319933f63c6d7494