Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Joshua Choi"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Do lymphatic vessels support cancer cells? Or are they vessels that help suppress cancer development? It is known that the lymphatic system is a vehicle for tumor metastasis and that the lymphangiogenic regulator VEGF-C supports the tumor. One such r
Externí odkaz:
https://doaj.org/article/0fb6bd426c6a4df2b10f0974dac4501a
Autor:
Patrick T. Rudak, Joshua Choi, Katie M. Parkins, Kelly L. Summers, Dwayne N. Jackson, Paula J. Foster, Anton I. Skaro, Ken Leslie, Vivian C. McAlister, Vijay K. Kuchroo, Wataru Inoue, Olivier Lantz, S.M. Mansour Haeryfar
Publikováno v:
Cell Reports, Vol 35, Iss 2, Pp 108979- (2021)
Summary: The deleterious effects of psychological stress on mainstream T lymphocytes are well documented. However, how stress impacts innate-like T cells is unclear. We report that long-term stress surprisingly abrogates both T helper 1 (TH1)- and TH
Externí odkaz:
https://doaj.org/article/6b28ec3ee5014eb1b4081f330d2f952d
Publikováno v:
Lipids in Health and Disease, Vol 16, Iss 1, Pp 1-11 (2017)
Abstract Background Efficacy-safety of proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitors, alirocumab (ALI) and evolocumab (EVO), have previously been evaluated through controlled clinical trials with selective patient groups. Post-comm
Externí odkaz:
https://doaj.org/article/961ace430720489f88ffa463eb50748a
Autor:
Eli B Nix, Joshua Choi, Christina Anthes, Gabrielle N Gaultier, Joelle Thorgrimson, Andrew D Cox, Raymond S W Tsang, William G McCready, Douglas Boreham, Marina Ulanova
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201282 (2018)
During the last two decades, Haemophilus influenzae serotype a (Hia) emerged as an important cause of invasive disease in Canadian First Nations and Inuit, and Alaskan Native populations, with the highest rates reported in young children. Immunocompe
Externí odkaz:
https://doaj.org/article/f5b186e643ef4ec7a8e8c5001ba1a445
Publikováno v:
Studies in Digital Heritage, Vol 1, Iss 2 (2017)
In an essay on architectural representation, Stan Allen (2000) wrote about a paradoxical nature of built forms: “Buildings are presumably more tangible and physically present than drawings, yet it is only in the experience of the building that the
Externí odkaz:
https://doaj.org/article/33040812bc244c72a758a3e1e6e7362f
Autor:
Christopher R Shaler, Joshua Choi, Patrick T Rudak, Arash Memarnejadian, Peter A Szabo, Mauro E Tun-Abraham, Jamie Rossjohn, Alexandra J Corbett, James McCluskey, John K McCormick, Olivier Lantz, Roberto Hernandez-Alejandro, S M Mansour Haeryfar
Publikováno v:
PLoS Biology, Vol 15, Iss 6, p e2001930 (2017)
Superantigens (SAgs) are potent exotoxins secreted by Staphylococcus aureus and Streptococcus pyogenes. They target a large fraction of T cell pools to set in motion a "cytokine storm" with severe and sometimes life-threatening consequences typically
Externí odkaz:
https://doaj.org/article/4b24ea4518434fc0a5371e496f1d85b0
Autor:
Joshua Choi, Crystal L Schmerk, Tina S Mele, Patrick T Rudak, Christine M Wardell, Gansen Deng, Farzan R Pavri, Kyoungok Kim, Gediminas Cepinskas, Wenqing He, SM Mansour Haeryfar
Publikováno v:
Immunology & Cell Biology. 101:249-261
Sepsis-elicited immunosuppression elevates the risk of secondary infections. We used a clinically relevant mouse model and serial peripheral blood samples from patients to assess the antimicrobial activities of mucosa-associated invariant T (MAIT) ce
Autor:
Michael A. Wheeler, Iain C. Clark, Hong-Gyun Lee, Zhaorong Li, Mathias Linnerbauer, Joseph M. Rone, Manon Blain, Camilo Faust Akl, Gavin Piester, Federico Giovannoni, Marc Charabati, Joon-Hyuk Lee, Yoon-Chul Kye, Joshua Choi, Liliana M. Sanmarco, Lena Srun, Elizabeth N. Chung, Lucas E. Flausino, Brian M. Andersen, Veit Rothhammer, Hiroshi Yano, Tomer Illouz, Stephanie E. J. Zandee, Carolin Daniel, David Artis, Marco Prinz, Adam R. Abate, Vijay K. Kuchroo, Jack P. Antel, Alexandre Prat, Francisco J. Quintana
Publikováno v:
Science
Cell–cell interactions in the central nervous system play important roles in neurologic diseases. However, little is known about the specific molecular pathways involved, and methods for their systematic identification are limited. Here, we develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::716c964e8fd9ff8c09dd7ebbf702e31d
https://europepmc.org/articles/PMC10066924/
https://europepmc.org/articles/PMC10066924/
Autor:
Dongwon Choi, Eunkyung Park, Roy P. Yu, Michael N. Cooper, Il-Taeg Cho, Joshua Choi, James Yu, Luping Zhao, Ji-Eun Irene Yum, Jin Suh Yu, Brandon Nakashima, Sunju Lee, Young Jin Seong, Wan Jiao, Chester J. Koh, Peter Baluk, Donald M. McDonald, Sindhu Saraswathy, Jong Y. Lee, Noo Li Jeon, Zhenqian Zhang, Alex S. Huang, Bin Zhou, Alex K. Wong, Young-Kwon Hong
Publikováno v:
Circulation Research. 131
Background: Mutations in PIEZO1 (Piezo type mechanosensitive ion channel component 1) cause human lymphatic malformations. We have previously uncovered an ORAI1 (ORAI calcium release-activated calcium modulator 1)-mediated mechanotransduction pathway
Autor:
Wataru Inoue, S. M. Mansour Haeryfar, Kelly L. Summers, Dwayne N. Jackson, Amer M. Burhan, Joshua Choi, Patrick T. Rudak, Rakshith Gangireddy
Publikováno v:
Brain, Behavior, and Immunity. 80:793-804
Stress is known to impede certain host defense mechanisms, including those governed by conventional T lymphocytes. However, whether innate-like T lymphocytes, such as invariant natural killer T (iNKT) and mucosa-associated invariant T (MAIT) cells, a