Zobrazeno 1 - 10
of 21 536
pro vyhledávání: '"Joshua C."'
Publikováno v:
Bone Research, Vol 12, Iss 1, Pp 1-16 (2024)
Abstract The human skeleton is a multifunctional organ made up of multiple cell types working in concert to maintain bone and mineral homeostasis and to perform critical mechanical and endocrine functions. From the beginning steps of chondrogenesis t
Externí odkaz:
https://doaj.org/article/025b037894cf4eaaac10c5bdf002ba03
Autor:
Ghislain Rocheleau, Shoa L. Clarke, Gaëlle Auguste, Natalie R. Hasbani, Alanna C. Morrison, Adam S. Heath, Lawrence F. Bielak, Kruthika R. Iyer, Erica P. Young, Nathan O. Stitziel, Goo Jun, Cecelia Laurie, Jai G. Broome, Alyna T. Khan, Donna K. Arnett, Lewis C. Becker, Joshua C. Bis, Eric Boerwinkle, Donald W. Bowden, April P. Carson, Patrick T. Ellinor, Myriam Fornage, Nora Franceschini, Barry I. Freedman, Nancy L. Heard-Costa, Lifang Hou, Yii-Der Ida Chen, Eimear E. Kenny, Charles Kooperberg, Brian G. Kral, Ruth J. F. Loos, Sharon M. Lutz, JoAnn E. Manson, Lisa W. Martin, Braxton D. Mitchell, Rami Nassir, Nicholette D. Palmer, Wendy S. Post, Michael H. Preuss, Bruce M. Psaty, Laura M. Raffield, Elizabeth A. Regan, Stephen S. Rich, Jennifer A. Smith, Kent D. Taylor, Lisa R. Yanek, Kendra A. Young, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Austin T. Hilliard, Catherine Tcheandjieu, Patricia A. Peyser, Ramachandran S. Vasan, Jerome I. Rotter, Clint L. Miller, Themistocles L. Assimes, Paul S. de Vries, Ron Do
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Whole genome sequences (WGS) enable discovery of rare variants which may contribute to missing heritability of coronary artery disease (CAD). To measure their contribution, we apply the GREML-LDMS-I approach to WGS of 4949 cases and 17,494 c
Externí odkaz:
https://doaj.org/article/06f5575dd28f4c74ac4e7a972d07a02f
Autor:
Shahzad Ahmad, Mohammad Aslam Imtiaz, Aniket Mishra, Ruiqi Wang, Marisol Herrera-Rivero, Joshua C. Bis, Myriam Fornage, Gennady Roshchupkin, Edith Hofer, Mark Logue, W. T. Longstreth, Rui Xia, Vincent Bouteloup, Thomas Mosley, Lenore J. Launer, Michael Khalil, Jens Kuhle, Robert A. Rissman, Genevieve Chene, Carole Dufouil, Luc Djoussé, Michael J. Lyons, Kenneth J. Mukamal, William S. Kremen, Carol E. Franz, Reinhold Schmidt, Stephanie Debette, Monique M. B. Breteler, Klaus Berger, Qiong Yang, Sudha Seshadri, N. Ahmad Aziz, Mohsen Ghanbari, M. Arfan Ikram
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract Neurofilament light chain (NfL) levels in circulation have been established as a sensitive biomarker of neuro-axonal damage across a range of neurodegenerative disorders. Elucidation of the genetic architecture of blood NfL levels could prov
Externí odkaz:
https://doaj.org/article/14e2c47872a446f281d0e204198d3b52
Autor:
Qianming Jiang, Matheus Castilho Galvão, Abdulrahman S. Alharthi, Ibrahim A. Alhidary, Mateus P. Gionbelli, Joshua C. McCann, Juan J. Loor
Publikováno v:
Ruminants, Vol 4, Iss 3, Pp 387-405 (2024)
We identified alterations in the ruminal microbiome, metabolome, and epithelial inflammatory response due to moderate feed restriction (FR). Ruminal digesta and epithelial biopsies from seven ruminally cannulated Angus steers were initially collected
Externí odkaz:
https://doaj.org/article/9e3e4ed544984af684157d9bcf3c44cc
Autor:
Robinson M. Ferre, Joshua C. Kaine, Daniela Lobo, Dina Peterson, Elisa Sarmiento, John Adame, Audrey Herbert, Paul M. Wallach, Frances M. Russell
Publikováno v:
BMC Medical Education, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Point of care ultrasound (POCUS) education has grown significantly over the past two decades. Like most curricular items, POCUS education is siloed within individual graduate medical education (GME) programs. The purpose of this s
Externí odkaz:
https://doaj.org/article/61723eea350b4de4a795136872825004
Autor:
Kylie K. Harmon, Ryan M. Girts, Gabriela Rodriguez, Jonathan P. Beausejour, Jason I. Pagan, Joshua C. Carr, Jeanette Garcia, Michael D. Roberts, Debbie L. Hahs‐Vaughn, Jeffrey R. Stout, David H. Fukuda, Matt S. Stock
Publikováno v:
Experimental Physiology, Vol 109, Iss 7, Pp 1145-1162 (2024)
Abstract Limb immobilization causes rapid declines in muscle strength and mass. Given the role of the nervous system in immobilization‐induced weakness, targeted interventions may be able to preserve muscle strength, but not mass, and vice versa. T
Externí odkaz:
https://doaj.org/article/5824d540f3e04465b22c607a433b63db
Publikováno v:
BioMed, Vol 4, Iss 2, Pp 171-184 (2024)
Existing implants used with Total Knee Arthroplasty (TKA), Total Hip Arthroplasty (THA), and other joint reconstruction treatments, have displayed premature failures and frequent needs for revision surgery in recent years, particularly with young act
Externí odkaz:
https://doaj.org/article/ce1402ba2a214cc4adb8afe1fbac66dd
Autor:
Hannah Meyer, Lexus Trosclair, Sean D. Clayton, Collyn O’Quin, Carol Crochet, Joshua C. Colvin, Valerie Welch, Ahmed Alhaque, Giovanni Solitro, Mila Shah-Bruce, J. Steven Alexander, Donald L. Sorrells
Publikováno v:
Pathophysiology, Vol 31, Iss 2, Pp 298-308 (2024)
Vaginal agenesis (VA) is frequently associated with mullerian agenesis. VA treatments include mechanical dilation and surgical vaginoplasty. We created a vaginal expansion sleeve (VES) as a novel device to progressively lengthen the vaginal canal. Th
Externí odkaz:
https://doaj.org/article/307e2413ac744e0a8d199c191459c645
Autor:
Rebecca Keener, Surya B. Chhetri, Carla J. Connelly, Margaret A. Taub, Matthew P. Conomos, Joshua Weinstock, Bohan Ni, Benjamin Strober, Stella Aslibekyan, Paul L. Auer, Lucas Barwick, Lewis C. Becker, John Blangero, Eugene R. Bleecker, Jennifer A. Brody, Brian E. Cade, Juan C. Celedon, Yi-Cheng Chang, L. Adrienne Cupples, Brian Custer, Barry I. Freedman, Mark T. Gladwin, Susan R. Heckbert, Lifang Hou, Marguerite R. Irvin, Carmen R. Isasi, Jill M. Johnsen, Eimear E. Kenny, Charles Kooperberg, Ryan L. Minster, Take Naseri, Satupa’itea Viali, Sergei Nekhai, Nathan Pankratz, Patricia A. Peyser, Kent D. Taylor, Marilyn J. Telen, Baojun Wu, Lisa R. Yanek, Ivana V. Yang, Christine Albert, Donna K. Arnett, Allison E. Ashley-Koch, Kathleen C. Barnes, Joshua C. Bis, Thomas W. Blackwell, Eric Boerwinkle, Esteban G. Burchard, April P. Carson, Zhanghua Chen, Yii-Der Ida Chen, Dawood Darbar, Mariza de Andrade, Patrick T. Ellinor, Myriam Fornage, Bruce D. Gelb, Frank D. Gilliland, Jiang He, Talat Islam, Stefan Kaab, Sharon L. R. Kardia, Shannon Kelly, Barbara A. Konkle, Rajesh Kumar, Ruth J. F. Loos, Fernando D. Martinez, Stephen T. McGarvey, Deborah A. Meyers, Braxton D. Mitchell, Courtney G. Montgomery, Kari E. North, Nicholette D. Palmer, Juan M. Peralta, Benjamin A. Raby, Susan Redline, Stephen S. Rich, Dan Roden, Jerome I. Rotter, Ingo Ruczinski, David Schwartz, Frank Sciurba, M. Benjamin Shoemaker, Edwin K. Silverman, Moritz F. Sinner, Nicholas L. Smith, Albert V. Smith, Hemant K. Tiwari, Ramachandran S. Vasan, Scott T. Weiss, L. Keoki Williams, Yingze Zhang, Elad Ziv, Laura M. Raffield, Alexander P. Reiner, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Hematology and Hemostasis Working Group, TOPMed Structural Variation Working Group, Marios Arvanitis, Carol W. Greider, Rasika A. Mathias, Alexis Battle
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Genome-wide association studies (GWAS) have become well-powered to detect loci associated with telomere length. However, no prior work has validated genes nominated by GWAS to examine their role in telomere length regulation. We conducted a
Externí odkaz:
https://doaj.org/article/3e293e6c932a4a42b553d789d690044b
Autor:
Jonathan A. O’Donnell, Michael P. Carey, Joshua C. Koch, Carson Baughman, Kenneth Hill, Christian E. Zimmerman, Patrick F. Sullivan, Roman Dial, Timothy Lyons, David J. Cooper, Brett A. Poulin
Publikováno v:
Communications Earth & Environment, Vol 5, Iss 1, Pp 1-10 (2024)
Abstract Climate change in the Arctic is altering watershed hydrologic processes and biogeochemistry. Here, we present an emergent threat to Arctic watersheds based on observations from 75 streams in Alaska’s Brooks Range that recently turned orang
Externí odkaz:
https://doaj.org/article/3bdbe0552c0447bdba4eafd50793d57a