Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Joshua B. Studdert"'
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2490
Here we describe a method to engraft epiblast stem cells (EpiSC) into the epiblast of gastrulation-stage mouse embryo to test the lineage propensity acquired by the EpiSCs during in vitro culture under different signaling conditions. After dissection
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2403
Analysis of animal models allows a deeper understanding of craniofacial development in health and diseases of humans. Wholemount in situ hybridization (WISH) is an informative technique to visualize gene expression in tissues across the developmental
Publikováno v:
Methods in Molecular Biology ISBN: 9781071618462
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40657c45ceb9679eda301491a8205f52
https://doi.org/10.1007/978-1-0716-1847-9_3
https://doi.org/10.1007/978-1-0716-1847-9_3
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2403
Craniofacial morphogenesis is underpinned by orchestrated growth and form-shaping activity of skeletal and soft tissues in the head and face. Disruptions during development can lead to dysmorphology of the skull, jaw, and the pharyngeal structures. D
Publikováno v:
Methods in Molecular Biology ISBN: 9781071618462
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::feac1eebb7479baaf01dc27fd0b6eac4
https://doi.org/10.1007/978-1-0716-1847-9_4
https://doi.org/10.1007/978-1-0716-1847-9_4
Autor:
Jing-Dong J. Han, Patrick P.L. Tam, Guangdun Peng, Joshua B. Studdert, Naihe Jing, Hwee Ngee Goh, Nazmus Salehin, Hilary Knowles, Xiaochen Fan, Nicolas Fossat, Emilie E. Wilkie, Poh-Lynn Khoo, Pierre Osteil
Publikováno v:
Development.
During embryogenesis, a stringent regulation of Wnt activity is critical for the morphogenesis of the head and brain. The loss of function of the Wnt inhibitor, Dkk1, results in elevated Wnt activity, loss of ectoderm lineage attributes from the ante
Autor:
David A.F. Loebel, Kristen Barratt, Vanessa Jones, Doreen Liebhold, Nicolas Fossat, Tania Radziewic, Melinda Power, Patrick P.L. Tam, Karin Tourle, Joshua B. Studdert
Publikováno v:
EMBO reports. 15:903-910
Cytidine (C) to Uridine (U) RNA editing is a post-transcriptional modification that is accomplished by the deaminase APOBEC1 and its partnership with the RNA-binding protein A1CF. We identify and characterise here a novel RNA-binding protein, RBM47,
Autor:
Vanessa Jones, Melinda Power, Joshua B. Studdert, Angelyn Hor, Kirsten A. Steiner, Yoji Kojima, David A.F. Loebel, Patrick P.L. Tam, Oliver H. Tam, Grant J Logan, Erdahl Teber, Keren Kaufman-Francis, Hilda A. Pickett, Gustavo de Alencastro, Michael D. Stutz, Ian E. Alexander
Publikováno v:
Cell Stem Cell. 14:107-120
SummaryMouse epiblast stem cells (EpiSCs) can be derived from a wide range of developmental stages. To characterize and compare EpiSCs with different origins, we derived a series of EpiSC lines from pregastrula stage to late-bud-stage mouse embryos.
Autor:
David A.F. Loebel, Vanessa Jones, Melinda Power, Kirsten A. Steiner, Lorraine Robb, Leigh Coultas, Renuka S. Rao, Nicolas Fossat, Patrick P.L. Tam, Yvette Jackson, Joshua B. Studdert, Tania Radziewic
Publikováno v:
Small GTPases
Rhou encodes a Cdc42-related atypical Rho GTPase that influences actin organization in cultured cells. In mouse embryos at early-somite to early-organogenesis stages, Rhou is expressed in the columnar endoderm epithelium lining the lateral and ventra
Autor:
Chi Kin Ip, Richard R. Behringer, Patrick P.L. Tam, Karin Tourle, David A.F. Loebel, Nicolas Fossat, Kin Ming Kwan, Joshua B. Studdert, Poh Lynn Khoo, Melinda Power, Vanessa Jones, Samara L. Lewis
Publikováno v:
Development (Cambridge, England). 142(11)
Lhx1 encodes a LIM homeobox transcription factor that is expressed in the primitive streak, mesoderm and anterior mesendoderm of the mouse embryo. Using a conditional Lhx1 flox mutation and three different Cre deleters, we demonstrated that LHX1 is r