Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Joshua B. Slee"'
Publikováno v:
Polymers, Vol 6, Iss 10, Pp 2526-2551 (2014)
Tissue contacting surfaces of medical devices initiate a host inflammatory response, characterized by adsorption of blood proteins and inflammatory cells triggering the release of cytokines, reactive oxygen species (ROS) and reactive nitrogen species
Externí odkaz:
https://doaj.org/article/34c815baeaaf4dfc8bbabfcd08399d52
Autor:
Kylee Shivok, Joshua B. Slee
Publikováno v:
BIOS. 93
Publikováno v:
Scholarship and Practice of Undergraduate Research. 4:49-61
A course-based undergraduate research experience (CURE) using cell culture–based research was developed to allow students to test potential molecules for their ability to prevent the host inflammatory response to implantable biomaterials. This CURE
Autor:
Walter A. Patton, Linda J. Lowe-Krentz, Raymond J. Pugh, Trista Barthol, Sara Lynn N. Farwell, Joshua B. Slee, Yaqiu Li
Publikováno v:
Journal of Biological Chemistry. 291:5326-5341
Vascular cell responses to exogenous heparin have been documented to include decreased vascular smooth muscle cell proliferation following decreased ERK pathway signaling. However, the molecular mechanism(s) by which heparin interacts with cells to i
Publikováno v:
Journal of Visualized Experiments.
When novel proteins are identified through affinity-based isolation and bioinformatics analysis, they are often largely uncharacterized. Antibodies against specific peptides within the predicted sequence allow some localization experiments. However,
Publikováno v:
CourseSource. 4
Publikováno v:
Polymers
Polymers, Vol 6, Iss 10, Pp 2526-2551 (2014)
Polymers, Vol 6, Iss 10, Pp 2526-2551 (2014)
Tissue contacting surfaces of medical devices initiate a host inflammatory response, characterized by adsorption of blood proteins and inflammatory cells triggering the release of cytokines, reactive oxygen species (ROS) and reactive nitrogen species
Autor:
Linda J. Lowe-Krentz, Joshua B. Slee
Publikováno v:
Journal of Cellular Biochemistry. 114:782-795
Vascular endothelial cells and their actin microfilaments align in the direction of fluid shear stress (FSS) in vitro and in vivo. To determine whether cofilin, an actin severing protein, is required in this process, the levels of phospho-cofilin (se
Autor:
Mark D. Cipolle, Elizabeth A. Miller, Joshua B. Slee, Sara Lynn N. Farwell, Marianne Hamel, Daniela Kanyi, Linda J. Lowe-Krentz
Despite the large number of heparin and heparan sulfate binding proteins, the molecular mechanism(s) by which heparin alters vascular cell physiology is not well understood. Studies with vascular smooth muscle cells (VSMCs) indicate a role for induct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b63b99c94dd97f9402b62ed2070008d6
https://europepmc.org/articles/PMC4777865/
https://europepmc.org/articles/PMC4777865/
Autor:
John W. Weisel, Ivan S. Alferiev, Robert J. Levy, Ilia Fishbein, Joshua B. Slee, Stanley J. Stachelek, Chandrasekaran Nagaswami
Publikováno v:
Biomaterials. 87
The effectiveness of endovascular stents is hindered by in-stent restenosis (ISR), a secondary re-obstruction of treated arteries due to unresolved inflammation and activation of smooth muscle cells in the arterial wall. We previously demonstrated th