Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Joshua B. Lowry"'
Autor:
Kenji Sugioka, Danielle R Hamill, Joshua B Lowry, Marie E McNeely, Molly Enrick, Alyssa C Richter, Lauren E Kiebler, James R Priess, Bruce Bowerman
Publikováno v:
eLife, Vol 6 (2017)
The centriole/basal body is a eukaryotic organelle that plays essential roles in cell division and signaling. Among five known core centriole proteins, SPD-2/Cep192 is the first recruited to the site of daughter centriole formation and regulates the
Externí odkaz:
https://doaj.org/article/64d199f2516e4d38bdba7c6e4891a0d7
Publikováno v:
Human Molecular Genetics. 27:1055-1066
Autosomal recessive loss-of-function mutations in N-glycanase 1 (NGLY1) cause NGLY1 deficiency, the only known human disease of deglycosylation. Patients present with developmental delay, movement disorder, seizures, liver dysfunction and alacrima. N
Autor:
Dominique Rasoloson, Matthew R. Wallenfang, Nadin Memar, Robert H. Waterston, Geraldine Seydoux, Mark L. Edgley, Vinci Au, John Yochem, Calvin Mok, Bruce Bowerman, Louis Gevirtzman, Joshua B. Lowry, Ralf Schnabel, Donald G. Moerman, Owen Thompson
Publikováno v:
Genetics. 207:447-463
Mutants remain a powerful means for dissecting gene function in model organisms such as Caenorhabditis elegans. Massively parallel sequencing has simplified the detection of variants after mutagenesis but determining precisely which change is respons
Publikováno v:
The Journal of Cell Biology
KLP-7/MCAK regulates kinetochore–microtubule attachment and spindle tension to promote the coalescence of early spindle pole foci, which produces a bipolar structure during the acentrosomal process of oocyte meiotic spindle assembly in C. elegans.<
Autor:
Robert H. Waterston, Geraldine Seydoux, Mark L. Edgley, Bruce Bowerman, Dominique Rasoloson, Nadin Memar, Joshua B. Lowry, John Yochem, Owen Thompson, Matthew R. Wallenfang, Calvin Mok, Donald G. Moerman, Vinci Au, Louis Gevirtzman, Ralf Schnabel
Temperature sensitive (TS) alleles are important tools for the genetic and functional analysis of essential genes in many model organisms. While isolating TS alleles is not difficult, determining the TS-conferring mutation can be problematic. Even wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1594c5ad4582c9a35dbd136ab4a66395
Autor:
Lauren E Kiebler, Danielle R Hamill, Alyssa C Richter, Bruce Bowerman, Kenji Sugioka, Joshua B. Lowry, James R. Priess, Molly Enrick, Marie E McNeely
Publikováno v:
eLife, Vol 6 (2017)
The centriole/basal body is a eukaryotic organelle that plays essential roles in cell division and signaling. Among five known core centriole proteins, SPD-2/Cep192 is the first recruited to the site of daughter centriole formation and regulates the
Autor:
Joshua B. Lowry, Marie E McNeely, Alyssa C Richter, Molly Enrick, Bruce Bowerman, Lauren E Kiebler, Danielle R Hamill, James R. Priess, Kenji Sugioka
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::557a6e2a5a969786090bdb46e5c77e0f
https://doi.org/10.7554/elife.20353.020
https://doi.org/10.7554/elife.20353.020
Autor:
Luke Carter, Nicholas Stiffler, Eric A. Johnson, Michael R. Miller, Amy A. Connolly, Nick Kamps-Hughes, John Yochem, Sean M. O'Rourke, Douglass W. Turnbull, Meredith H. Price, Bruce Bowerman, Joshua B. Lowry
Publikováno v:
Genetics
Forward genetic screens provide a powerful approach for inferring gene function on the basis of the phenotypes associated with mutated genes. However, determining the causal mutation by traditional mapping and candidate gene sequencing is often the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c771b54e87027b340acb4932d9f8794e
https://europepmc.org/articles/PMC3213368/
https://europepmc.org/articles/PMC3213368/