Zobrazeno 1 - 10
of 222
pro vyhledávání: '"Joshua B Edel"'
Autor:
Chayachon Apiwat, Jack W. Houghton, Ren Ren, Edward Tate, Joshua B. Edel, Narong Chanlek, Patraporn Luksirikul, Deanpen Japrung
Publikováno v:
ACS Omega, Vol 9, Iss 39, Pp 40592-40607 (2024)
Externí odkaz:
https://doaj.org/article/4243bd359b9b4826894fb1b56ccb9986
Autor:
Ren Ren, Shenglin Cai, Xiaona Fang, Xiaoyi Wang, Zheng Zhang, Micol Damiani, Charlotte Hudlerova, Annachiara Rosa, Joshua Hope, Nicola J. Cook, Peter Gorelkin, Alexander Erofeev, Pavel Novak, Anjna Badhan, Michael Crone, Paul Freemont, Graham P. Taylor, Longhua Tang, Christopher Edwards, Andrew Shevchuk, Peter Cherepanov, Zhaofeng Luo, Weihong Tan, Yuri Korchev, Aleksandar P. Ivanov, Joshua B. Edel
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract We report on single-molecule nanopore sensing combined with position-encoded DNA molecular probes, with chemistry tuned to simultaneously identify various antigen proteins and multiple RNA gene fragments of SARS-CoV-2 with high sensitivity a
Externí odkaz:
https://doaj.org/article/1aeae1396aa84739853d9656c3d758c3
Publikováno v:
Research, Vol 7 (2024)
Biocompatible connections between external artificial devices and living organisms show promise for future neuroprosthetics and therapeutics. The study in Science by Zhao and colleagues introduces a cascade-heterogated biphasic gel (HBG) iontronic de
Externí odkaz:
https://doaj.org/article/ad616f67cc5e445cbc160a6063e8dcb2
Autor:
Alexander J. Ainscough, Timothy J. Smith, Maike Haensel, Christopher J. Rhodes, Adam Fellows, Harry J. Whitwell, Eleni Vasilaki, Kelly Gray, Adrian Freeman, Luke S. Howard, John Wharton, Benjamin Dunmore, Paul D. Upton, Martin R. Wilkins, Joshua B. Edel, Beata Wojciak-Stothard
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
A biomimetic inducible model of pulmonary arterial hypertension (PAH) is presented, combining natural and induced BMPR2 dysfunction with hypoxia in lung endothelial cells and blood-derived PAH cells to induce smooth muscle activation & proliferation.
Externí odkaz:
https://doaj.org/article/23b65781f0864f158a058def624a88d9
Autor:
Shenglin Cai, Thomas Pataillot-Meakin, Akifumi Shibakawa, Ren Ren, Charlotte L. Bevan, Sylvain Ladame, Aleksandar P. Ivanov, Joshua B. Edel
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
miRNA profiling from patient blood can be used for cancer diagnosis. Here the authors present an electro-optical nanopore sensing platform which allows sensitive and specific miRNA detection directly in human serum and apply to monitoring of miR-141-
Externí odkaz:
https://doaj.org/article/d3c563e3e37e455093e426357d5c1670
Autor:
Sang-Hyun Oh, Hatice Altug, Xiaojia Jin, Tony Low, Steven J. Koester, Aleksandar P. Ivanov, Joshua B. Edel, Phaedon Avouris, Michael S. Strano
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
This review presents an overview of scenarios where van der Waals (vdW) materials provide unique advantages for nanophotonic biosensing applications. The authors discuss basic sensing principles based on vdW materials, advantages of the reduced dimen
Externí odkaz:
https://doaj.org/article/a28aa6ec52f64ac482de6c79272a28e5
Autor:
Longhua Tang, Binoy Paulose Nadappuram, Paolo Cadinu, Zhiyu Zhao, Liang Xue, Long Yi, Ren Ren, Jiangwei Wang, Aleksandar P. Ivanov, Joshua B. Edel
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Abstract Quantum tunnelling offers a unique opportunity to study nanoscale objects with atomic resolution using electrical readout. However, practical implementation is impeded by the lack of simple, stable probes, that are required for successful op
Externí odkaz:
https://doaj.org/article/20f17a5127d0420fbb2edabc0e595c3a
Autor:
Peter A. Summers, Benjamin W. Lewis, Jorge Gonzalez-Garcia, Rosa M. Porreca, Aaron H. M. Lim, Paolo Cadinu, Nerea Martin-Pintado, David J. Mann, Joshua B. Edel, Jean Baptiste Vannier, Marina K. Kuimova, Ramon Vilar
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Direct observation of G-quadruplexes (G4s) in live cells is challenging. Here the authors report a method to identify G4s within the nuclei of live and fixed cells using a fluorescent probe combined with fluorescence lifetime imaging microscopy.
Externí odkaz:
https://doaj.org/article/37fc31773c234ea49cb172f66805dd72
Autor:
Yanjun Zhang, Yasufumi Takahashi, Sung Pil Hong, Fengjie Liu, Joanna Bednarska, Philip S. Goff, Pavel Novak, Andrew Shevchuk, Sahana Gopal, Iros Barozzi, Luca Magnani, Hideki Sakai, Yoshimoto Suguru, Takuto Fujii, Alexander Erofeev, Peter Gorelkin, Alexander Majouga, Dominik J. Weiss, Christopher Edwards, Aleksandar P. Ivanov, David Klenerman, Elena V. Sviderskaya, Joshua B. Edel, Yuri Korchev
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Current methods to measure extracellular pH are often limited in resolution and response times. Here the authors present a label-free nanoprobe, consisting of a zwitterionic nanomembrane at the tip of a nanopipette, which enables high spatiotemporal
Externí odkaz:
https://doaj.org/article/ebd98ca7f57c46df9f47297895059247
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Nanopore detection of small molecules can be improved using molecular carriers, but separating a small analyte from the carrier signal can be challenging. Here the authors address this challenge using simultaneous electrical and optical readout in na
Externí odkaz:
https://doaj.org/article/3aa322cfb567432698be53e2febb90a6