Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Joshua A. Tobin"'
Autor:
Shravan Leonard-Murali, Chetana Bhaskarla, Ghanshyam S. Yadav, Sudeep K. Maurya, Chenna R. Galiveti, Joshua A. Tobin, Rachel J. Kann, Eishan Ashwat, Patrick S. Murphy, Anish B. Chakka, Vishal Soman, Paul G. Cantalupo, Xinming Zhuo, Gopi Vyas, Dara L. Kozak, Lindsey M. Kelly, Ed Smith, Uma R. Chandran, Yen-Michael S. Hsu, Udai S. Kammula
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Immune checkpoint inhibition has shown success in treating metastatic cutaneous melanoma but has limited efficacy against metastatic uveal melanoma, a rare variant arising from the immune privileged eye. To better understand this resistance,
Externí odkaz:
https://doaj.org/article/c3827bd8a22341ebb07936043ec06ea7
Autor:
Deepak Bararia, Johannes A. Hildebrand, Sebastian Stolz, Sarah Haebe, Stefan Alig, Christopher P. Trevisani, Francisco Osorio-Barrios, Michael D. Bartoschek, Michael Mentz, Alessandro Pastore, Erik Gaitzsch, Michael Heide, Vindi Jurinovic, Katharina Rautter, Jay Gunawardana, Muhammed B. Sabdia, Monika Szczepanowski, Julia Richter, Wolfram Klapper, Abner Louissaint, Jr., Christina Ludwig, Sebastian Bultmann, Heinrich Leonhardt, Sebastian Eustermann, Karl-Peter Hopfner, Wolfgang Hiddemann, Michael von Bergwelt-Baildon, Christian Steidl, Robert Kridel, Joshua W.D. Tobin, Maher K. Gandhi, David M. Weinstock, Marc Schmidt-Supprian, Menyhárt B. Sárosi, Martina Rudelius, Verena Passerini, Josef Mautner, Oliver Weigert
Publikováno v:
Cell Reports, Vol 31, Iss 5, Pp - (2020)
Summary: Tumor cells orchestrate their microenvironment. Here, we provide biochemical, structural, functional, and clinical evidence that Cathepsin S (CTSS) alterations induce a tumor-promoting immune microenvironment in follicular lymphoma (FL). We
Externí odkaz:
https://doaj.org/article/0a5e722ca6e94029b574353537c7475f
Autor:
Eliza A Hawkes, Jake Shortt, Greg Hapgood, Belinda A. Campbell, Dejan Radeski, Sze Ting Lee, Maya Latimer, Stephen Lade, Joshua W.D. Tobin, Henry Miles Prince, Bryone J. Kuss, D Purtill
Publikováno v:
Internal Medicine Journal. 52:1806-1817
Peripheral T-cell lymphomas (PTCLs) represent a heterogeneous disease group accounting for 10% of non-Hodgkin lymphomas. PTCL patients have typically poorer outcomes compared to aggressive B-cell lymphomas. However, such outcomes are heavily dependen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb98485529ec656eda264f771a13b798
https://doi.org/10.1111/imj.15595
https://doi.org/10.1111/imj.15595
Publikováno v:
mSphere, Vol 4, Iss 1 (2019)
Externí odkaz:
https://doaj.org/article/342393de76e649fd806dd5ce446d6d46
Publikováno v:
mSphere, Vol 3, Iss 5 (2018)
ABSTRACT Grf10, a homeodomain-containing transcription factor, regulates adenylate and one-carbon metabolism and morphogenesis in the human fungal pathogen Candida albicans. Here, we identified functional domains and key residues involved in transcri
Externí odkaz:
https://doaj.org/article/a010629c8a494a91a0a3fce172fda088
Autor:
Anna Crothers, Paul Anthony Scuffham, Greg Hapgood, Ti Eric Ma, Joshua W.D. Tobin, Maher K. Gandhi, Peter Mollee
Publikováno v:
Leukemia & Lymphoma. 62:3484-3492
Recent data suggest the use of radiotherapy alone (RT) in Early-Stage Follicular Lymphoma is declining. Cost-effectiveness analysis of treatments has not been performed. We constructed a partitioning model (15-year horizon) to compare RT, combined-mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a86ae240d7e4d99641aba06a546f9360
https://doi.org/10.1080/10428194.2021.1957866
https://doi.org/10.1080/10428194.2021.1957866
Publikováno v:
Resuscitation. 163:130-135
Introduction Drowning results in more than 360,000 deaths annually, making it the 3rd leading cause of unintentional injury death worldwide. Prior studies have examined airway interventions affecting patient outcomes in cardiac arrest, but less is kn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5499461f0946d9152fdab96bac1a870
https://doi.org/10.1016/j.resuscitation.2020.12.027
https://doi.org/10.1016/j.resuscitation.2020.12.027
Autor:
Joshua A. Tobin, Shivang Joshi, Janet H. Ford, Russell M. Nichols, Shonda A. Foster, Dustin Ruff, Holland C. Detke, Sheena K. Aurora
Publikováno v:
Journal of medical economics. 25(1)
To analyze secondary objectives of the REGAIN study related to acute headache medication use and healthcare resource utilization (HCRU) in patients with chronic migraine treated with galcanezumab, a monoclonal antibody to calcitonin gene-related pept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aab3fef46bc2e3a284c7fc4c45307b9
https://pubmed.ncbi.nlm.nih.gov/35971655
https://pubmed.ncbi.nlm.nih.gov/35971655
Autor:
Joshua M. Tobin
Publikováno v:
Cardiovascular Engineering and Technology. 12:526-529
Current quantitative descriptions of the cardiovascular system in hemorrhagic shock focus on pressure based metrics. This approach is often incomplete; overlooking the important role of tissue perfusion. Electrical analogs to the cardiovascular syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c839faccc0f8c723aa7c7112d999841
https://doi.org/10.1007/s13239-021-00545-8
https://doi.org/10.1007/s13239-021-00545-8
Autor:
Samantha A Hershenfeld, Victoria Shelton, Mehran Bakhtiari, Lourdes Calvente, Katherine Lajkosz, Keren Isaev, Anjali Silva, Ting Liu, Marianne Brodtkorb, Francesco Annibale d'Amore, Maja Ludvigsen, Charlotte Madsen, Stephen Hamilton-Dutoit, Maher Gandhi, Joshua W.D. Tobin, Tara Baetz, David LeBrun, Nathalie A. Johnson, Andrew J. Mungall, Michael Crump, Jan Delabie, Mary Gospodarowicz, David Hodgson, Michael Hong, Vishal Kukreti, John Kuruvilla, Anca Prica, Rosemarie Tremblay-Lemay, Richard Tsang, Robert Kridel
Publikováno v:
Blood. 140:3532-3533
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0287bd9e544e042ead135bab376f88f7
https://doi.org/10.1182/blood-2022-156571
https://doi.org/10.1182/blood-2022-156571