Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Joshua A. Kuleape"'
Autor:
Anbarasu Kumaraswamy, Zhi Duan, Diana Flores, Chao Zhang, Archana Sehrawat, Ya-Mei Hu, Olivia A. Swaim, Eva Rodansky, William K. Storck, Joshua A. Kuleape, Karan Bedi, Rahul Mannan, Xiao-Ming Wang, Aaron Udager, Visweswaran Ravikumar, Armand Bankhead III, Ilsa Coleman, John K. Lee, Colm Morrissey, Peter S. Nelson, Arul M. Chinnaiyan, Arvind Rao, Zheng Xia, Joel A. Yates, Joshi J. Alumkal
Publikováno v:
JCI Insight, Vol 8, Iss 15 (2023)
Lysine-specific demethylase 1 (LSD1) is a histone demethylase that promotes stemness and cell survival in cancers such as prostate cancer. Most prostate malignancies are adenocarcinomas with luminal differentiation. However, some tumors undergo cellu
Externí odkaz:
https://doaj.org/article/e4a07a2910524a9eab732b3ab8ace38b
Autor:
Caleb Kwame Sinclear, Junichi Maruyama, Shunta Nagashima, Kyoko Arimoto‐Matsuzaki, Joshua Agbemefa Kuleape, Hiroaki Iwasa, Hiroshi Nishina, Yutaka Hata
Publikováno v:
Cancer Science. 113:1305-1320
Yes-associated protein 1 (YAP1) interacts with TEAD transcription factor in the nucleus and upregulates TEAD-target genes. YAP1 is phosphorylated by large tumor suppressor (LATS) kinases, the core kinases of the Hippo pathway, at 5 serine residues an
Autor:
Joshua Agbemefa Kuleape, Emmanuel Ayitey Tagoe, Peter Puplampu, Evelyn Yayra Bonney, Osbourne Quaye
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0195954 (2018)
Glutathione S-transferase (GST) family of enzymes are involved in a two-stage detoxification process of a wide range of environmental toxins, carcinogens and xenobiotics. The GST enzymes play important roles in oxidative stress pathways, and polymorp
Externí odkaz:
https://doaj.org/article/e00a73a9926e43d9b9aeee923509db04
Autor:
Joshua Agbemefa Kuleape, Shakhawoat Hossain, Caleb Kwame Sinclear, Takanobu Shimizu, Hiroaki Iwasa, Junichi Maruyama, Kyoko Arimoto-Matsuzaki, Hiroshi Nishina, Yutaka Hata
Publikováno v:
Mol Cell Biol
RASSF6, a member of the tumor suppressor Ras-association domain family (RASSF) proteins, regulates cell cycle arrest and apoptosis via p53 and plays a tumor suppressor role. We previously reported that RASSF6 blocks MDM2-mediated p53 degradation and
Autor:
Seth .D. Amanquah, Peter Puplampu, Ishmael Nii Ayibontey Tagoe, Emmanuel Ayitey Tagoe, Osbourne Quaye, Joshua Agbemefa Kuleape, Henry Asare-Anane
Publikováno v:
Tropical Medicine & International Health. 24:766-774
Highly active antiretroviral therapy (HAART) has considerably reduced HIV/AIDS-related morbidity and mortality; however, the therapy has been associated with the development of cardiovascular disease (CVD), and genetic predisposition factors may aggr
Autor:
Joshua Agbemefa Kuleape, Peter Puplampu, Emmanuel Ayitey Tagoe, Evelyn Y. Bonney, Osbourne Quaye
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 7, p e0220181 (2019)
PLoS ONE, Vol 14, Iss 7, p e0220181 (2019)
Human immunodeficiency virus (HIV) infection and antiretroviral therapy (ART) have been associated with high oxidative stress in HIV patients. The disparity in antioxidant-oxidant levels in HIV patients favours viral replication and disease progressi
Autor:
Peter Puplampu, Evelyn Y. Bonney, Osbourne Quaye, Emmanuel Ayitey Tagoe, Joshua Agbemefa Kuleape
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 5, p e0195954 (2018)
PLoS ONE, Vol 13, Iss 5, p e0195954 (2018)
Glutathione S-transferase (GST) family of enzymes are involved in a two-stage detoxification process of a wide range of environmental toxins, carcinogens and xenobiotics. The GST enzymes play important roles in oxidative stress pathways, and polymorp
Autor:
Osbourne Quaye, Joshua Agbemefa Kuleape, Evelyn Yayra Bonney, Peter Puplampu, Emmanuel Ayitey Tagoe
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0220181 (2019)
Human immunodeficiency virus (HIV) infection and antiretroviral therapy (ART) have been associated with high oxidative stress in HIV patients. The disparity in antioxidant-oxidant levels in HIV patients favours viral replication and disease progressi
Externí odkaz:
https://doaj.org/article/d8af27354e504d86b97e31a23e1fd892