Zobrazeno 1 - 10
of 279
pro vyhledávání: '"Joshua A. Gordon"'
Autor:
Taylor J. Malone, Nai-Wen Tien, Yan Ma, Lian Cui, Shangru Lyu, Garret Wang, Duc Nguyen, Kai Zhang, Maxym V. Myroshnychenko, Jean Tyan, Joshua A. Gordon, David A. Kupferschmidt, Yi Gu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract The medial entorhinal cortex (MEC) is hypothesized to function as a cognitive map for memory-guided navigation. How this map develops during learning and influences memory remains unclear. By imaging MEC calcium dynamics while mice successfu
Externí odkaz:
https://doaj.org/article/1ff095d633f44923979cb8b6a5b90c73
Autor:
Dakota F. Brockway, Keith R. Griffith, Chloe M. Aloimonos, Thomas T. Clarity, J. Brody Moyer, Grace C. Smith, Nigel C. Dao, Md Shakhawat Hossain, Patrick J. Drew, Joshua A. Gordon, David A. Kupferschmidt, Nicole A. Crowley
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112976- (2023)
Summary: We sought to characterize the unique role of somatostatin (SST) in the prelimbic (PL) cortex in mice. We performed slice electrophysiology in pyramidal and GABAergic neurons to characterize the pharmacological mechanism of SST signaling and
Externí odkaz:
https://doaj.org/article/6d6c0587838643a4b9fa5f7bc88a9bac
Autor:
Sarah E. Morris, Charles A. Sanislow, Jenni Pacheco, Uma Vaidyanathan, Joshua A. Gordon, Bruce N. Cuthbert
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-11 (2022)
Abstract Background In 2013, a few years after the launch of the National Institute of Mental Health’s Research Domain Criteria (RDoC) initiative, Cuthbert and Insel published a paper titled “Toward the future of psychiatric diagnosis: the seven
Externí odkaz:
https://doaj.org/article/70ef920e5841458aa775fa55f7920c7d
Autor:
Daniel C. Lowes, Linda A. Chamberlin, Lisa N. Kretsge, Emma S. Holt, Atheir I. Abbas, Alan J. Park, Lyubov Yusufova, Zachary H. Bretton, Ayesha Firdous, Armen G. Enikolopov, Joshua A. Gordon, Alexander Z. Harris
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Acute stress transiently disrupts reward-seeking behaviour and repeated stress exposure produces lasting anhedonia-like behaviour in rodents. Here, the authors show that stress triggers GABAergic activity in the ventral tegmental area which blunts re
Externí odkaz:
https://doaj.org/article/00c4ef5a5a704504b5b5820961797043
Autor:
Matthew T. Simons, Abdulaziz H. Haddab, Joshua A. Gordon, David Novotny, Christopher L. Holloway
Publikováno v:
IEEE Access, Vol 7, Pp 164975-164985 (2019)
We demonstrate a Rydberg atom-based sensor embedded in a parallel-plate waveguide (PPWG) for amplitude and phase detection of a radio-frequency (RF) electric field. This embedded atomic sensor is also capable of receiving modulated communications sig
Externí odkaz:
https://doaj.org/article/13a3be48dee14f15a2b82a638cb37c1e
Autor:
Nora D. Volkow, George F. Koob, Robert T. Croyle, Diana W. Bianchi, Joshua A. Gordon, Walter J. Koroshetz, Eliseo J. Pérez-Stable, William T. Riley, Michele H. Bloch, Kevin Conway, Bethany G. Deeds, Gayathri J. Dowling, Steven Grant, Katia D. Howlett, John A. Matochik, Glen D. Morgan, Margaret M. Murray, Antonio Noronha, Catherine Y. Spong, Eric M. Wargo, Kenneth R. Warren, Susan R.B. Weiss
Publikováno v:
Developmental Cognitive Neuroscience, Vol 32, Iss , Pp 4-7 (2018)
Adolescence is a time of dramatic changes in brain structure and function, and the adolescent brain is highly susceptible to being altered by experiences like substance use. However, there is much we have yet to learn about how these experiences infl
Externí odkaz:
https://doaj.org/article/0e10e90631814349a111245524928f78
Publikováno v:
Robotics, Vol 10, Iss 4, p 124 (2021)
In this work, we present methods allowing parallel, hybrid, and serial manipulators to be analyzed, calibrated, and controlled with the same analytical tools. We introduce a general approach to describe any robotic manipulator using established seria
Externí odkaz:
https://doaj.org/article/e329b300e07c437783b2217241dbb10b
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Theta- and gamma-frequency oscillatory synchrony correlates with spatial working memory performance. Here the authors report increases in theta-gamma cross-frequency coupling as a compensatory mechism associated with better working memory performance
Externí odkaz:
https://doaj.org/article/0a4e40e9395942198e3c246bdf143b55
Publikováno v:
Computational Psychiatry, Vol 1, Pp 2-23 (2017)
This article provides an illustrative treatment of psychiatric morbidity that offers an alternative to the standard nosological model in psychiatry. It considers what would happen if we treated diagnostic categories not as causes of signs and symptom
Externí odkaz:
https://doaj.org/article/8ced4e5047934e2faf0772c4e4c63e7b
Publikováno v:
Cell Reports, Vol 17, Iss 2, Pp 570-582 (2016)
Proline dehydrogenase (PRODH), which degrades L-proline, resides within the schizophrenia-linked 22q11.2 deletion suggesting a role in disease. Supporting this, elevated L-proline levels have been shown to increase risk for psychotic disorders. Despi
Externí odkaz:
https://doaj.org/article/73face7b50904d78af564f76aaa1113b