Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Joshua A. Dubland"'
Autor:
Joshua A. Dubland
Publikováno v:
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 23, Iss , Pp 7-13 (2022)
Ion mobility spectrometry (IMS) is an analytical technique where ions are separated in the gas phase based on their mobility through a buffer gas in the presence of an electric field. An ion passing through an IMS device has a characteristic collisio
Externí odkaz:
https://doaj.org/article/7a8e64199cd04c748c91d8585c20ec92
Publikováno v:
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 20, Iss , Pp 1-10 (2021)
Inborn errors of propionate, cobalamin and methionine metabolism are targets for Newborn Screening (NBS) in most programs world-wide, and are primarily screened by analyzing for propionyl carnitine (C3) and methionine in dried blood spot (DBS) cards
Externí odkaz:
https://doaj.org/article/7194934e3c43437c96bc4be6d7b3ef31
Autor:
Ramesh Saeedi, Ali Mojebi-Mogharar, Supna K. Sandhu, Joshua A. Dubland, Jo-Ann Ford, Masoud Yousefi, Morris Pudek, Daniel T. Holmes, Siegfried R. Erb, Wing C. Peter Kwan, David L Kendler, Eric M. Yoshida
Publikováno v:
Annals of Hepatology, Vol 16, Iss 2, Pp 207-214 (2017)
Background. Patients with chronic hepatitis B virus (HBV) are often treated with nucleoside/nucleotide antiviral agents and metabolic bone toxicity is a possible concern.Objective. To determine the relationships between fibroblast growth factor 23 (F
Externí odkaz:
https://doaj.org/article/bb7188e7b0ef46db8d80447d6b84672a
Publikováno v:
Pediatric Nephrology. 37:1347-1353
The presence of ketone bodies (KBs) can interfere with creatinine (Cr) measurement in both enzymatic and Jaffe methods. Since a high proportion of children hospitalized for diabetic ketoacidosis (DKA) develop acute kidney injury (AKI), here we invest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8e8f3aa0e8fa7238bb83635121e1a97
https://doi.org/10.1007/s00467-021-05324-0
https://doi.org/10.1007/s00467-021-05324-0
Publikováno v:
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 20, Iss, Pp 1-10 (2021)
Journal of Mass Spectrometry and Advances in the Clinical Lab
Journal of Mass Spectrometry and Advances in the Clinical Lab
Highlights • Analysis of 2-methylcitric acid, methylmalonic acid, and homocysteine in DBS. • A dual derivatization LC-MS/MS strategy developed for use in second-tier NBS. • Second-tier panel replaces multiple initial follow-up tests. • Improv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50beebd48c7a916d499a13356b9284c0
https://doi.org/10.1016/j.jmsacl.2021.03.001
https://doi.org/10.1016/j.jmsacl.2021.03.001
Publikováno v:
Clinical biochemistry.
Urine organic acids profiling by gas chromatography-mass spectrometry (GC-MS) is routinely performed in hospital biochemical genetics laboratories for the investigation of inborn errors of metabolism. In particular, accurate identification of urinary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9822134cf6c8dc3a8b56f5ecf7b46a3c
https://pubmed.ncbi.nlm.nih.gov/35500672
https://pubmed.ncbi.nlm.nih.gov/35500672
Autor:
Joshua A Dubland, Gordon A Francis
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 3 (2015)
Unregulated cellular uptake of apolipoprotein B-containing lipoproteins in the arterial intima leads to the formation of foam cells in atherosclerosis. Lysosomal acid lipase (LAL) plays a crucial role in both lipoprotein lipid catabolism and excess l
Externí odkaz:
https://doaj.org/article/2d08c79ccfb94760a0043b9dfb383f89
Autor:
Ying Wang, Basak Sahin, Michael A. Seidman, Don D. Sin, Gordon A. Francis, Nicholas J. Leeper, Joshua A. Dubland, Sima Allahverdian, Jen Erh Jaw, Enyinnaya Asonye
Publikováno v:
Arterioscler Thromb Vasc Biol
Objective— Smooth muscle cells (SMCs) are the most abundant cells in human atherosclerotic lesions and are suggested to contribute at least 50% of atheroma foam cells. In mice, SMCs contribute fewer total lesional cells. The purpose of this study w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deefea3f77db8b9f50b3191b30fe3f8d
https://doi.org/10.1161/atvbaha.119.312434
https://doi.org/10.1161/atvbaha.119.312434
Publikováno v:
Current Opinion in Lipidology. 30:117-124
Purpose of review Smooth muscle cells (SMCs) are the major cell type in human atherosclerosis-prone arteries and take up excess lipids, thereby contributing to luminal occlusion. Here we provide a focused review on pathways by which smooth muscle cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caab060e6440a5b46cf98213a82f18fe
https://doi.org/10.1097/mol.0000000000000574
https://doi.org/10.1097/mol.0000000000000574
Autor:
Collin S Pryma, Carleena Ortega, Katrina J. Besler, Teddy Chan, Joshua A. Dubland, Ying Wang, Michael A. Seidman, Sima Allahverdian, Gordon A. Francis, Kamel Boukais
Publikováno v:
Arterioscler Thromb Vasc Biol
Objective: We previously reported smooth muscle cells (SMCs) represent ≥50% of foam cells in human coronary and ≈70% in apoE (apolipoprotein E)-deficient mouse aortic atheromas and exhibit reduced expression of the cholesterol exporter ABCA1 (ATP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::506e6b5abd23067e88ebb0a04c406a41
https://pubmed.ncbi.nlm.nih.gov/33853350
https://pubmed.ncbi.nlm.nih.gov/33853350