Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Joshua A. Benne"'
Autor:
Paula R. Chen, Raymond R. R. Rowland, Ana M. Stoian, Vlad Petrovan, Maureen Sheahan, Charan Ganta, Giselle Cino-Ozuna, Dae Young Kim, James M. Dunleavey, Kristin M. Whitworth, Melissa S. Samuel, Lee D. Spate, Raissa F. Cecil, Joshua A. Benne, Xingyu Yan, Ying Fang, Brad St. Croix, Kelly Lechtenberg, Kevin D. Wells, Randall S. Prather
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Senecavirus A (SVA) is a cause of vesicular disease in pigs, and infection rates are rising within the swine industry. Recently, anthrax toxin receptor 1 (ANTXR1) was revealed as the receptor for SVA in human cells. Herein, the role of ANTXR
Externí odkaz:
https://doaj.org/article/2a7f2ae4bfcc4e1b94db3d06a2d64dec
Autor:
Erik A. Koppes, Bethany K. Redel, Marie A. Johnson, Kristen J. Skvorak, Lina Ghaloul-Gonzalez, Megan E. Yates, Dale W. Lewis, Susanne M. Gollin, Yijen L. Wu, Shawn E. Christ, Martine Yerle, Angela Leshinski, Lee D. Spate, Joshua A. Benne, Stephanie L. Murphy, Melissa S. Samuel, Eric M. Walters, Sarah A. Hansen, Kevin D. Wells, Uta Lichter-Konecki, Robert A. Wagner, Joseph T. Newsome, Steven F. Dobrowolski, Jerry Vockley, Randall S. Prather, Robert D. Nicholls
Publikováno v:
JCI Insight, Vol 5, Iss 20 (2020)
Phenylalanine hydroxylase–deficient (PAH-deficient) phenylketonuria (PKU) results in systemic hyperphenylalaninemia, leading to neurotoxicity with severe developmental disabilities. Dietary phenylalanine (Phe) restriction prevents the most deleteri
Externí odkaz:
https://doaj.org/article/25a4c7bc5404441d96bc2b097f4c68db
Autor:
Bethany K Redel, Benjamin P Beaton, Lee D Spate, Joshua A Benne, Stephanie L Murphy, Chad W O’Gorman, Anna M Spate, Randall S Prather, Kevin D Wells
Publikováno v:
BioTechniques, Vol 64, Iss 3, Pp 118-124 (2018)
Production of Cas9 mRNA in vitro typically requires the addition of a 5´ cap and 3´ polyadenylation. A plasmid was constructed that harbored the T7 promoter followed by the EMCV IRES and a Cas9 coding region. We hypothesized that the use of the met
Externí odkaz:
https://doaj.org/article/0c50dbd04e8e4a50b5173c1f244c4e26
Autor:
Paula R Chen, Randall S. Prather, Joshua A. Benne, Lee D. Spate, Taylor K. Hord, Raissa F. Cecil, Melissa Samuel
Publikováno v:
Molecular Reproduction and Development
To improve efficiency of somatic cell nuclear transfer (SCNT), it is necessary to modify differentiated donor cells to become more amendable for reprogramming by the oocyte cytoplasm. A key feature that distinguishes somatic/differentiated cells from
Autor:
Joshua A. Benne, Gregory W. Burns, Martha S Ortega, L. H. Aguiar, Thomas E. Spencer, Gabriela H. Pedroza, Kelsey E. Brooks, Anna C. Denicol, Eleanore V O'Neil
Publikováno v:
Molecular Reproduction and Development. 87:142-151
Conceptus development and elongation is required for successful pregnancy establishment in ruminants and is coincident with the production of interferon τ (IFNT) and prostaglandins (PGs). In both the conceptus trophectoderm and endometrium, PGs are
Autor:
Paula R. Chen, Raymond R. R. Rowland, Ana M. Stoian, Vlad Petrovan, Maureen Sheahan, Charan Ganta, Giselle Cino-Ozuna, Dae Young Kim, James M. Dunleavey, Kristin M. Whitworth, Melissa S. Samuel, Lee D. Spate, Raissa F. Cecil, Joshua A. Benne, Xingyu Yan, Ying Fang, Brad St. Croix, Kelly Lechtenberg, Kevin D. Wells, Randall S. Prather
Publikováno v:
Scientific reports. 12(1)
Senecavirus A (SVA) is a cause of vesicular disease in pigs, and infection rates are rising within the swine industry. Recently, anthrax toxin receptor 1 (ANTXR1) was revealed as the receptor for SVA in human cells. Herein, the role of ANTXR1 as a re
Autor:
Thomas E. Spencer, Michael F. Smith, Megan K McLean, Melissa Samuel, Ashley E Meyer, Joshua A. Benne, Clifton N. Murphy, Lee D. Spate, Rodney D. Geisert, Caroline A Pfeiffer, Kevin D. Wells, Raissa F. Cecil, Susanta K. Behura, Randall S. Prather, Lauren A Ciernia, Kelsey E. Brooks, Kristin M. Whitworth
Publikováno v:
Biology of Reproduction. 101:148-161
The proposed signal for maternal recognition of pregnancy in pigs is estrogen (E2), produced by the elongating conceptuses between days 11 to 12 of pregnancy with a more sustained increase during conceptus attachment and placental development on days
Autor:
Melissa Samuel, Kevin D. Wells, Bethany R. Mordhorst, Kristin M. Whitworth, Raissa F. Cecil, Lee D. Spate, Jonathan A. Green, Clifton N. Murphy, Randall S. Prather, Joshua A. Benne
Publikováno v:
Molecular Reproduction and Development
Genetically engineered pigs serve as excellent biomedical and agricultural models. To date, the most reliable way to generate genetically engineered pigs is via somatic cell nuclear transfer (SCNT), however, the efficiency of cloning in pigs is low (
Autor:
Robert Wagner, Kevin D. Wells, Steven F. Dobrowolski, Susanne M. Gollin, Robert D. Nicholls, Yijen L. Wu, Marie A. Johnson, Eric M. Walters, Erik A. Koppes, Sarah A. Hansen, M Yerle, Shawn E. Christ, Dale W. Lewis, Melissa Samuel, Joseph T. Newsome, Kristen J. Skvorak, Megan E. Yates, Lina Ghaloul-Gonzalez, Randall S. Prather, Uta Lichter-Konecki, Stephanie L. Murphy, Lee D. Spate, Joshua A. Benne, Jerry Vockley, Bethany K. Redel, Angela Leshinski
Publikováno v:
JCI Insight
JCI Insight, American Society for Clinical Investigation, 2020, 5 (20), ⟨10.1172/jci.insight.141523⟩
JCI Insight, Vol 5, Iss 20 (2020)
JCI Insight, American Society for Clinical Investigation, 2020, 5 (20), ⟨10.1172/jci.insight.141523⟩
JCI Insight, Vol 5, Iss 20 (2020)
Phenylalanine hydroxylase–deficient (PAH-deficient) phenylketonuria (PKU) results in systemic hyperphenylalaninemia, leading to neurotoxicity with severe developmental disabilities. Dietary phenylalanine (Phe) restriction prevents the most deleteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85254df3b5697eb1b6ace05dcedc976c
https://hal.inrae.fr/hal-03158896
https://hal.inrae.fr/hal-03158896
Autor:
Randall S. Prather, Joshua A. Benne, Lee D. Spate, Raissa F. Cecil, Taylor K. Hord, Eric C. Leffeler, Paula R Chen
Publikováno v:
Molecular Reproduction and Development
Hypotaurine (HT) is a routine component of porcine embryo culture medium, functioning as an antioxidant, but its requirement may be diminished as most embryo culture systems now use 5% O2 instead of atmospheric (20%) O2. Our objective was to determin