Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Joshua A. Bagley"'
Autor:
Shan Meltzer, Joshua A. Bagley, Gerardo Lopez Perez, Caitlin E. O’Brien, Laura DeVault, Yanmeng Guo, Lily Yeh Jan, Yuh-Nung Jan
Publikováno v:
Cell Reports, Vol 21, Iss 4, Pp 859-866 (2017)
Summary: Disruptions in lipid homeostasis have been observed in many neurodevelopmental disorders that are associated with dendrite morphogenesis defects. However, the molecular mechanisms of how lipid homeostasis affects dendrite morphogenesis are u
Externí odkaz:
https://doaj.org/article/d901711a896c4637ab29b66523841162
Autor:
Ulrich Elling, Arndt von Haeseler, Florian G. Pflug, Simon Haendeler, Johannes Zuber, Benoit Schroeder, Dominik Lindenhofer, Christopher Esk, Joshua A. Bagley, Jürgen A. Knoblich, Roelof A. Wester
Publikováno v:
Science
Functional screen for microcephaly genes Genetic screens are widely used to identify regulators in biological processes. Human screens are currently limited to two-dimensional cell cultures, which lack the ability to score tissue-dependent gene funct
Autor:
Sunanjay Bajaj, Sakurako Nagumo Wong, Julie Lévi-Strauss, Joshua A. Bagley, Juergen A. Knoblich, Ábel Vértesy, Veronica Krenn, Christoph Sommer
Publikováno v:
EMBO J
Inhibitory GABAergic interneurons migrate over long distances from their extracortical origin into the developing cortex. In humans, this process is uniquely slow and prolonged, and it is unclear whether guidance cues unique to humans govern the vari
Publikováno v:
JBJS reviews. 9(4)
» Radial head arthroplasty is a viable surgical option when a radial head fracture cannot be reconstructed. Radial head arthroplasty provides a load-bearing articular structure against the capitellum in unstable fractured elbows. » Studies have emp
Publikováno v:
JBJS Open Access, Vol 6, Iss 4 (2021)
JBJS Open Access
JBJS Open Access
Background:. Medical knowledge and technical skills are foundations of surgical competency. The American Board of Orthopaedic Surgery (ABOS) and the Resident Review Committee for Orthopaedic Surgery recently mandated simulation training to improve su
Autor:
Gerardo Lopez Perez, Caitlin E. O’Brien, Joshua A. Bagley, Laura DeVault, Lily Yeh Jan, Yuh Nung Jan, Shan Meltzer, Yanmeng Guo
Publikováno v:
Cell Reports, Vol 21, Iss 4, Pp 859-866 (2017)
Cell reports, vol 21, iss 4
Cell reports, vol 21, iss 4
Summary: Disruptions in lipid homeostasis have been observed in many neurodevelopmental disorders that are associated with dendrite morphogenesis defects. However, the molecular mechanisms of how lipid homeostasis affects dendrite morphogenesis are u
Autor:
Ho Min Kim, Myeong Hoon Han, Sung Bae Lee, Do Young Hyeon, Byung Su Ko, Yun Mi Lee, Min Jee Kwon, Daehee Hwang, In Jun Cha, Dong Young Kim, Yuh Nung Jan, Seung Yeol Kim, Joshua A. Bagley
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 115, iss 45
Neurodegenerative disorders, such as Huntington's diseases and spinocerebellar ataxias (SCAs), are driven by proteins with expanded polyglutamine (polyQ) tracts. Recently, coiled-coil structures in polyQ regions of such proteins were shown to facilit
Publikováno v:
Protocol Exchange.
Development of the forebrain involves the migration of GABAergic interneurons over long distances from ventral into dorsal regions. Although defects in interneuron migration are implicated in neuropsychiatric diseases such as Epilepsy, Autism, and Sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1ca377370bac8f8a3a1389c4c467e43
https://doi.org/10.1101/131250
https://doi.org/10.1101/131250
Publikováno v:
Genes & Development. 28:1940-1956
A complex array of genetic factors regulates neuronal dendrite morphology. Epigenetic regulation of gene expression represents a plausible mechanism to control pathways responsible for specific dendritic arbor shapes. By studying the Drosophila dendr