Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Joshua A Granek"'
Autor:
Calla L Telzrow, Paul J Zwack, Shannon Esher Righi, Fred S Dietrich, Cliburn Chan, Kouros Owzar, J Andrew Alspaugh, Joshua A Granek
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 11 (2021)
AbstractRNA sequencing (RNA-Seq) experiments focused on gene expression involve removal of ribosomal RNA (rRNA) because it is the major RNA constituent of cells. This process, called RNA enrichment, is done primarily to reduce cost: without rRNA remo
Externí odkaz:
https://doaj.org/article/1f1e7f4c0f8d42818c119b3b8b401db4
Autor:
Sheng Sun, Vikas Yadav, R Blake Billmyre, Christina A Cuomo, Minou Nowrousian, Liuyang Wang, Jean-Luc Souciet, Teun Boekhout, Betina Porcel, Patrick Wincker, Joshua A Granek, Kaustuv Sanyal, Joseph Heitman
Publikováno v:
PLoS Biology, Vol 15, Iss 8, p e2002527 (2017)
Species within the human pathogenic Cryptococcus species complex are major threats to public health, causing approximately 1 million annual infections globally. Cryptococcus amylolentus is the most closely known related species of the pathogenic Cryp
Externí odkaz:
https://doaj.org/article/21db1a6222ae423e908494e1234c46d3
Autor:
Eve W L Chow, Shelly A Clancey, R Blake Billmyre, Anna Floyd Averette, Joshua A Granek, Piotr Mieczkowski, Maria E Cardenas, Joseph Heitman
Publikováno v:
PLoS Genetics, Vol 13, Iss 4, p e1006667 (2017)
Calcineurin is a highly conserved Ca2+/calmodulin-dependent serine/threonine-specific protein phosphatase that orchestrates cellular Ca2+ signaling responses. In Cryptococcus neoformans, calcineurin is activated by multiple stresses including high te
Externí odkaz:
https://doaj.org/article/dfe7e5afecf14621a9f0266cad3d30f9
Autor:
Kaila M. Pianalto, Calla L. Telzrow, Hannah Brown Harding, Jacob T. Brooks, Joshua A. Granek, Eduardo Gushiken-Ibañez, Salomé LeibundGut-Landmann, Joseph Heitman, Giuseppe Ianiri, J. Andrew Alspaugh
Publikováno v:
mBio, Vol 15, Iss 10 (2024)
ABSTRACT During mammalian colonization and infection, microorganisms must be able to rapidly sense and adapt to changing environmental conditions including alterations in extracellular pH. The fungus-specific Rim/Pal signaling pathway is one process
Externí odkaz:
https://doaj.org/article/dada565781b7409a9bc8099b6a4d1b79
Autor:
Joshua A Granek, Laure Pisella, John Stemberger, Alain Vighetto, Yves Rossetti, Lauren E Sergio
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e86138 (2013)
Guiding a limb often involves situations in which the spatial location of the target for gaze and limb movement are not congruent (i.e. have been decoupled). Such decoupled situations involve both the implementation of a cognitive rule (i.e. strategi
Externí odkaz:
https://doaj.org/article/c3f76aa4fef14e29bbb01072010112ce
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46619 (2012)
Patients with optic ataxia (OA), who are missing the caudal portion of their superior parietal lobule (SPL), have difficulty performing visually-guided reaches towards extra-foveal targets. Such gaze and hand decoupling also occurs in commonly perfor
Externí odkaz:
https://doaj.org/article/6cb3122ed9964940bef4376ac351bd7d
Autor:
Joshua A Granek, Paul M Magwene
Publikováno v:
PLoS Genetics, Vol 6, Iss 1, p e1000823 (2010)
Nutrient stresses trigger a variety of developmental switches in the budding yeast Saccharomyces cerevisiae. One of the least understood of such responses is the development of complex colony morphology, characterized by intricate, organized, and str
Externí odkaz:
https://doaj.org/article/fc26580f268446febe6b0b1eb8393ef5
Autor:
Danielle Nettere, Shakthi Unnithan, Nicole Rodgers, Junsuke Nohara, Paul Cray, Madison Berry, Caroline Jones, Lawrence Armand, Shuk Hang Li, Stella J. Berendam, Genevieve G. Fouda, Derek W. Cain, Taylor N. Spence, Joshua A. Granek, Clemontina A. Davenport, Robert J. Edwards, Kevin Wiehe, Koen K. A. Van Rompay, M. Anthony Moody, Sallie R. Permar, Justin Pollara
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-15 (2023)
Abstract An effective HIV-1 vaccine remains a critical unmet need for ending the AIDS epidemic. Vaccine trials conducted to date have suggested the need to increase the durability and functionality of vaccine-elicited antibodies to improve efficacy.
Externí odkaz:
https://doaj.org/article/47723f7571494d1382df246f734a90c6
Autor:
Calla L. Telzrow, Shannon Esher Righi, Jackson M. Cathey, Joshua A. Granek, J. Andrew Alspaugh
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Introduction: Microbial pathogens undergo significant physiological changes during interactions with the infected host, including alterations in metabolism and cell architecture. The Cryptococcus neoformans Mar1 protein is required for the proper ord
Externí odkaz:
https://doaj.org/article/bda29b4a63e8443080efdf9034719958
Autor:
Michael E. Lidsky, Zechen Wang, Min Lu, Annie Liu, S. David Hsu, Shannon J. McCall, Zhecheng Sheng, Joshua A. Granek, Kouros Owzar, Karen S. Anderson, Kris C. Wood
Publikováno v:
NPJ precision oncology. 6(1)
Intrahepatic cholangiocarcinoma (ICC) remains a deadly malignancy lacking systemic therapies for advanced disease. Recent advancements include selective FGFR1–3 inhibitors for the 15% of ICC patients harboring fusions, although survival is limited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76ca431df9613ff699474b76a3fd16e7
https://pubmed.ncbi.nlm.nih.gov/36274097
https://pubmed.ncbi.nlm.nih.gov/36274097