Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Joshua A Chu-Tan"'
Autor:
Yvette Wooff, Nilisha Fernando, Josephine H. C. Wong, Catherine Dietrich, Riemke Aggio-Bruce, Joshua A. Chu-Tan, Avril A. B. Robertson, Sarah L. Doyle, Si Ming Man, Riccardo Natoli
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-3 (2024)
Externí odkaz:
https://doaj.org/article/0b42afea808f428c96da1b32ffbd34be
Autor:
Yvette Wooff, Adrian V. Cioanca, Elly Wills, Joshua A. Chu-Tan, Rakshanya Sekar, Riccardo Natoli
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionAge-related macular degeneration (AMD) is the leading cause of blindness in the developed world, currently affecting over 350 billion people globally. For the most prevalent late-stage form of this disease, atrophic AMD, there are no avai
Externí odkaz:
https://doaj.org/article/859ce25eeee54fbfb8205c4dc0d493fe
Autor:
Joshua A. Chu-Tan, Adrian V. Cioanca, Yvette Wooff, Max Kirkby, Marissa Ellis, Pranay Gulati, Tim Karl, Jeffrey H. Boatright, Katie Bales, John Nickerson, Riccardo Natoli
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Background: Exercise has been shown to promote a healthier and longer life and linked to a reduced risk of developing neurodegenerative diseases including retinal degenerations. However, the molecular pathways underpinning exercise-induced cellular p
Externí odkaz:
https://doaj.org/article/5bc5c860b3b44c759c0f1b6a685c192d
Autor:
Joshua A. Chu-Tan, Adrian V. Cioanca, Zhi-Ping Feng, Yvette Wooff, Ulrike Schumann, Riemke Aggio-Bruce, Hardip Patel, Matt Rutar, Katherine Hannan, Konstantin Panov, Jan Provis, Riccardo Natoli
Publikováno v:
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-21 (2021)
Abstract Background MicroRNA (miRNA) play a significant role in the pathogenesis of complex neurodegenerative diseases including age-related macular degeneration (AMD), acting as post-transcriptional gene suppressors through their association with ar
Externí odkaz:
https://doaj.org/article/e8092aeac0204c3e936b785d776b9dc5
Autor:
Nilisha Fernando, Josephine H. C. Wong, Shannon Das, Catherine Dietrich, Riemke Aggio-Bruce, Adrian V. Cioanca, Yvette Wooff, Joshua A. Chu-Tan, Ulrike Schumann, Chinh Ngo, Rohan W. Essex, Camilla Dorian, Sarah A. Robertson, Si Ming Man, Jan Provis, Riccardo Natoli
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
IntroductionMicroRNAs (miRNAs) are small, non-coding RNA molecules that have powerful regulatory properties, with the ability to regulate multiple messenger RNAs (mRNAs) and biological pathways. MicroRNA-223-3p (miR-223) is known to be a critical reg
Externí odkaz:
https://doaj.org/article/0fef47723931438ea4faac0fc6890274
Autor:
Yvette Wooff, Adrian V. Cioanca, Joshua A. Chu-Tan, Riemke Aggio-Bruce, Ulrike Schumann, Riccardo Natoli
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Photoreceptor cell death and inflammation are known to occur progressively in retinal degenerative diseases such as age-related macular degeneration (AMD). However, the molecular mechanisms underlying these biological processes are largely unknown. E
Externí odkaz:
https://doaj.org/article/6c82a65ef8ec4c99a575b171b89f4bd4
Autor:
Riccardo Natoli, Nilisha Fernando, Michele Madigan, Joshua A. Chu-Tan, Krisztina Valter, Jan Provis, Matt Rutar
Publikováno v:
Molecular Neurodegeneration, Vol 12, Iss 1, Pp 1-11 (2017)
Abstract Background Chemokine signalling is required for the homing of leukocytes during retinal inflammation, and is associated with pathogenesis of diseases such as age-related macular degeneration (AMD). Here, we explore the role of interleukin-1
Externí odkaz:
https://doaj.org/article/7659da9dc07e4b47b56fb1ea803c1d7a
Publikováno v:
Clinical & Experimental Ophthalmology. 50:74-90
The benefits of exercise to human health have long been recognised. However, only in the past decade have researchers started to discover the molecular benefits that exercise confers, especially to the central nervous system (CNS). These discoveries
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7899d00fbeeef8ff6f3ce312ec4d2dfd
https://doi.org/10.1111/ceo.14023
https://doi.org/10.1111/ceo.14023
Autor:
Joshua A. Chu-Tan, Matt Rutar, Kartik Saxena, Yunlu Wu, Lauren Howitt, Krisztina Valter, Jan Provis, Riccardo Natoli
Publikováno v:
International Journal of Photoenergy, Vol 2016 (2016)
Photobiomodulation at a wavelength of 670 nm has been shown to be effective in preventing photoreceptor cell death in the retina. We treated Sprague-Dawley (SD) rats with varying doses of 670 nm light (9; 18; 36; 90 J/cm2) before exposing them to dif
Externí odkaz:
https://doaj.org/article/053e98aefbfe48038152981055040440
Autor:
Riemke Aggio-Bruce, Joshua A Chu-Tan, Adrian V Cioanca, Ulrike Schumann, Riccardo Natoli, Yvette Wooff
Publikováno v:
Molecular Neurobiology
Although extensively investigated in inflammatory conditions, the role of pro-inflammatory microRNAs (miRNAs), miR-155 and miR-146a, has not been well-studied in retinal degenerative diseases. We therefore aimed to explore the role and regulation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0345c7ec47a6a1119ba3a47b698f183c
https://doi.org/10.1007/s12035-020-02158-z
https://doi.org/10.1007/s12035-020-02158-z