Zobrazeno 1 - 10
of 365
pro vyhledávání: '"Joshua A Beckman"'
Autor:
Shi Huang, Joshua A Beckman, Eric Farber-Eger, Quinn S Wells, Timothy E Thayer, Evan L Brittain, Jonathan D Mosley
Publikováno v:
Open Heart, Vol 8, Iss 2 (2021)
Objective Red cell distribution width (RDW) is an enigmatic biomarker associated with the presence and severity of multiple cardiovascular diseases (CVDs). It is unclear whether elevated RDW contributes to, results from, or is pleiotropically related
Externí odkaz:
https://doaj.org/article/289da3ba3f394200a4ae9f212d7307dc
Autor:
Joshua A Beckman, Brian R Wood, Kevin L Ard, Christin N Price, Daniel A Solomon, Jonah P Zuflacht, Jessica Milian, Joshua C Prenner, Paul E Sax
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0181993 (2017)
Bilirubin acts as a potent endogenous antioxidant, with higher concentrations associated with lower rates of CVD; the antiretroviral drug atazanavir (ATV) increases bilirubin levels but may also increase von Willebrand factor levels. We tested the hy
Externí odkaz:
https://doaj.org/article/ade110dc54fa4720b7b70372ee5112bb
Autor:
Victoria E. Thomas, Joshua A. Beckman
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 21 (2024)
Peripheral artery disease (PAD) is a progressive atherosclerotic disease that causes lower extremity arterial stenosis or occlusion. Patients with PAD are at increased risk of myocardial infarction, stroke, limitations in ambulation, and amputation.
Externí odkaz:
https://doaj.org/article/43060339a0354b05a87a5beb3c1aec38
Autor:
Mingjian Shi, Chuan Wang, Hao Mei, Marinella Temprosa, Jose C. Florez, Mark Tripputi, Jordi Merino, Loren Lipworth, Xiao‐Ou Shu, Robert E. Gerszten, Thomas J. Wang, Joshua A. Beckman, Jorge L. Gamboa, Jonathan D. Mosley, Jane F. Ferguson
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 11 (2022)
Background Elevated plasma levels of alpha‐aminoadipic acid (2‐AAA) have been associated with the development of type 2 diabetes and atherosclerosis. However, the nature of the association remains unknown. Methods and Results We identified geneti
Externí odkaz:
https://doaj.org/article/bfc48ec14d9c4498899ac92527ab1799
Autor:
Mona Mashayekhi, Joshua A. Beckman, Erica M. Garner, Hui Nian, Chang Yu, Sara E. Howard, Bradley Perkins, Jessica K. Devin, John R. Koethe, Jonathan D. Brown, Heidi Silver, James M. Luther, Nancy J. Brown
Publikováno v:
Journal of Clinical and Translational Science, Vol 6, Pp 81-82 (2022)
OBJECTIVES/GOALS: We aimed to determine if GLP-1 receptor agonists exert beneficial effects on surrogate measures of cardiovascular function independently of weight loss. Our objective was to compare the outcomes between GLP-1 receptor agonist treatm
Externí odkaz:
https://doaj.org/article/21dc8ed76ef642acaa3cbc8d1458f414
Autor:
Joshua A. Beckman, MD, Sean P. Doherty, BA, Zachary B. Feldman, BA, Emily S. Banks, BS, Javid Moslehi, MD, Iris Z. Jaffe, MD, PhD, Naomi M. Hamburg, MD, Quanhu Sheng, PhD, Jonathan D. Brown, MD
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 5, Pp 567-574 (2019)
Summary: In this study low-input RNA-sequencing was used to annotate the molecular identity of endothelial cells isolated and immunopurified with CD144 microbeads. Using this technique, comparative gene expression profiling from healthy subjects and
Externí odkaz:
https://doaj.org/article/b728fbf090354e778a680e203eefa2d7
Autor:
Mona Mashayekhi, Joshua A. Beckman, Hui Nian, Erica M. Garner, Dustin Mayfield, Jessica K. Devin, John R. Koethe, Jonathan D. Brown, Katherine N. Cahill, Chang Yu, Heidi Silver, Kevin Niswender, James M. Luther, Nancy J. Brown
Publikováno v:
Diabetes, Obesity and Metabolism. 25:570-580
To test the hypothesis that glucagon-like peptide-1 receptor (GLP-1R) agonists have beneficial effects on vascular endothelial function, fibrinolysis and inflammation through weight loss-independent mechanisms.Individuals with obesity and prediabetes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1554ab2fcd3086f366e34393195f86fa
https://doi.org/10.1111/dom.14903
https://doi.org/10.1111/dom.14903
Autor:
Hiral Master, Jeffrey Annis, Shi Huang, Joshua A. Beckman, Francis Ratsimbazafy, Kayla Marginean, Robert Carroll, Karthik Natarajan, Frank E. Harrell, Dan M. Roden, Paul Harris, Evan L. Brittain
Publikováno v:
Nature Medicine. 28:2301-2308
The association between physical activity and human disease has not been examined using commercial devices linked to electronic health records. Using the electronic health records data from the All of Us Research Program, we show that step count volu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48c989aa9eeb6f37856c900ec80df93c
https://doi.org/10.1038/s41591-022-02012-w
https://doi.org/10.1038/s41591-022-02012-w
Autor:
Patrick M. Kozak, Meng Xu, Eric Farber‐Eger, David Gailani, Quinn S. Wells, Joshua A. Beckman
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 22 (2019)
Background The value of thrombophilia test acquisition in improving risk prediction beyond clinical presentation remains unknown. We investigated the effect of thrombophilia test acquisition on venous thromboembolism (VTE) outcomes. Methods and Resul
Externí odkaz:
https://doaj.org/article/c051f74baa274dd1b47b1b16d2edc79d
Autor:
Celestine N. Wanjalla, Tecla M. Temu, Mona Mashayekhi, Christian M. Warren, Bryan E. Shepherd, Rama Gangula, Hubaida Fuseini, Samuel Bailin, Curtis L. Gabriel, Pandu Gangula, Meena S. Madhur, Spyros Kalams, Simon A. Mallal, David G. Harrison, Joshua A. Beckman, John R. Koethe
Publikováno v:
AIDS
OBJECTIVE: Chronic inflammation contributes to the high burden of cardiovascular disease (CVD) in persons with HIV (PWH). HIV has broad effects on innate and adaptive immune cells, including innate lymphoid cells (ILCs) and CD4(+) T-helper cells. At
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::162c0d7a5a3f71434e352aed9cc254a9
https://pubmed.ncbi.nlm.nih.gov/35165215
https://pubmed.ncbi.nlm.nih.gov/35165215