Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Joshua A, Mancini"'
Autor:
Jennifer Timm, Douglas H. Pike, Joshua A. Mancini, Alexei M. Tyryshkin, Saroj Poudel, Jan A. Siess, Paul M. Molinaro, James J. McCann, Kate M. Waldie, Ronald L. Koder, Paul G. Falkowski, Vikas Nanda
The most ancient processes for energy production in the evolution of life involve the reversible oxidation of molecular hydrogen by hydrogenase. Extant hydrogenase enzymes are complex, comprising hundreds of amino acids and multiple cofactors. We des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::526222fd361adc0f520d778601ea1a96
https://doi.org/10.1101/2022.04.09.487740
https://doi.org/10.1101/2022.04.09.487740
Autor:
Rosalind E. M. Rickaby, Paul G. Falkowski, Saroj Poudel, Douglas H. Pike, Vikas Nanda, Hagai Raanan, Joshua A. Mancini
Publikováno v:
Proc Natl Acad Sci U S A
Ribulose 1,5-bisphosphate carboxylase/oxygenase (RuBisCO) is the most abundant enzyme on Earth. However, its catalytic rate per molecule of protein is extremely slow and the binding of the primary substrate, CO2, is competitively displaced by O2. Hen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f41781fb95571517af39c8b49598845
https://doi.org/10.1073/pnas.2018939117
https://doi.org/10.1073/pnas.2018939117
Autor:
Michael H. Hecht, Alexei M. Tyryshkin, Douglas H. Pike, Joshua A. Mancini, Vikas Nanda, Michael S. Wang, Saroj Poudel, Liti Haramaty
Publikováno v:
Biotechnology and Applied Biochemistry. 67:574-585
We explore the capacity of the de novo protein, S824, to incorporate a multinuclear iron-sulfur cluster within the core of a single-chain four-helix bundle. This topology has a high intrinsic designability because sequences are constrained largely by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66475934e66bc840e6303ca636bfca64
https://doi.org/10.1002/bab.2003
https://doi.org/10.1002/bab.2003
Autor:
Alexei M. Tyryshkin, Joshua A. Mancini, Vikas Nanda, Jennifer Timm, Douglas H. Pike, Paul G. Falkowski, Saroj Poudel
Publikováno v:
Goldschmidt2021 abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3fcd6c8d37c231f993628ee4d2588a2
https://doi.org/10.7185/gold2021.7964
https://doi.org/10.7185/gold2021.7964
Autor:
Joshua A, Mancini, Douglas H, Pike, Alexei M, Tyryshkin, Liti, Haramaty, Michael S, Wang, Saroj, Poudel, Michael, Hecht, Vikas, Nanda
Publikováno v:
Biotechnology and applied biochemistryReferences. 67(4)
We explore the capacity of the de novo protein, S824, to incorporate a multinuclear iron-sulfur cluster within the core of a single-chain four-helix bundle. This topology has a high intrinsic designability because sequences are constrained largely by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8fd8392840510415e3dbaed5a358e2ab
https://pubmed.ncbi.nlm.nih.gov/32770861
https://pubmed.ncbi.nlm.nih.gov/32770861
Autor:
Michael S. Magaraci, Christopher C. Moser, Ivan A. Kuznetsov, P. Leslie Dutton, Joshua A. Mancini, Molly M. Sheehan, Goutham Kodali, Brian Y. Chow
Publikováno v:
Biochemistry
We report the rational construction of a de novo-designed biliverdin-binding protein by first principles of protein design, informed by energy minimization modeling in Rosetta. The self-assembling tetrahelical bundles bind biliverdin IXa (BV) cofacto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f43aef3543e2a3e1157369bd2d655150
http://europepmc.org/articles/PMC6293442
http://europepmc.org/articles/PMC6293442
Autor:
Goutham Kodali, Joshua A. Mancini, Pawel Wagner, David L. Officer, Christopher J. Hobbs, Christopher C. Moser, Lee A. Solomon, Jonathan E. Barnsley, Kunche Aravindu, Nicholas Roach, Tatiana V. Episova, P. Leslie Dutton, Olga Mass, Keith C. Gordon
Publikováno v:
Chemical Science
Design of nanometer scale artificial light harvesting and charge separating proteins enables reengineering to overcome the limitations of natural selection for efficient systems that better meet human energetic needs.
Natural selection in photos
Natural selection in photos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d3814d2461b81c53883c3a6f659dff0
https://doi.org/10.1039/c6sc02417c
https://doi.org/10.1039/c6sc02417c
Autor:
Päivi Törmä, Anna Lishchuk, P. Leslie Dutton, Goutham Kodali, Olga Mass, Brice Darroch, C. Neil Hunter, Joshua A. Mancini, Matthew Broadbent, Graham J. Leggett, Aleksey Nabok
In strong plasmon-exciton coupling, a surface plasmon mode is coupled to an array of localized emitters to yield new hybrid light-matter states (plexcitons), whose properties may in principle be controlled via modification of the arrangement of emitt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6110d35ed6029bdc8b81406d90a96aa5
https://shura.shu.ac.uk/21740/1/Nabok-SyntheticBiologicalQuantumOpticalSystem(VoR).pdf
https://shura.shu.ac.uk/21740/1/Nabok-SyntheticBiologicalQuantumOpticalSystem(VoR).pdf
Publikováno v:
Mechanisms of Primary Energy Transduction in Biology ISBN: 9781782628651
A practical understanding of first-principles directed protein folding in de novo protein design and the factors that control intraprotein electron tunnelling in both natural and artificial proteins allows the planned design of artificial counterpart
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55320a9f2988b8883e2cc2a78529a074
https://doi.org/10.1039/9781788010405-00001
https://doi.org/10.1039/9781788010405-00001
Autor:
Joshua A. Mancini, Bohdana M. Discher, Chris Bialas, Dirk B. Auman, Tatiana V. Esipova, Nathan M. Ennist, P. Leslie Dutton, Christopher C. Moser, Martin J. Iwanicki
Publikováno v:
Photosynthesis and Bioenergetics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2871adf392202f3a87ec2c5967773ba3
https://doi.org/10.1142/9789813230309_0001
https://doi.org/10.1142/9789813230309_0001