Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Joshua C. Vaughan"'
Autor:
Jeffrey W. Pippin, Natalya Kaverina, Yuliang Wang, Diana G. Eng, Yuting Zeng, Uyen Tran, Carol J. Loretz, Anthony Chang, Shreeram Akilesh, Chetan Poudel, Hannah S. Perry, Christopher O’Connor, Joshua C. Vaughan, Markus Bitzer, Oliver Wessely, Stuart J. Shankland
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 16 (2022)
With an aging population, kidney health becomes an important medical and socioeconomic factor. Kidney aging mechanisms are not well understood. We previously showed that podocytes isolated from aged mice exhibit increased expression of programmed cel
Externí odkaz:
https://doaj.org/article/6f35f7a0c54e416aa558e94eded1b8d9
Autor:
Jason C. Klima, Lindsey A. Doyle, Justin Daho Lee, Michael Rappleye, Lauren A. Gagnon, Min Yen Lee, Emilia P. Barros, Anastassia A. Vorobieva, Jiayi Dou, Samantha Bremner, Jacob S. Quon, Cameron M. Chow, Lauren Carter, David L. Mack, Rommie E. Amaro, Joshua C. Vaughan, Andre Berndt, Barry L. Stoddard, David Baker
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Fluorescent protein reporters based on GFP exist, but have intrinsic disadvantages. Here the authors incorporate pH, Ca2+ and protein–protein interaction sensing modalities into de novo designed mini-fluorescence-activating proteins (mFAPs), with i
Externí odkaz:
https://doaj.org/article/5f1531b0f2b14a3183076ec5a9a3c859
Autor:
William R Hardin, Germain C M Alas, Nikita Taparia, Elizabeth B Thomas, Melissa C Steele-Ogus, Kelli L Hvorecny, Aaron R Halpern, Pavla Tůmová, Justin M Kollman, Joshua C Vaughan, Nathan J Sniadecki, Alexander R Paredez
Publikováno v:
PLoS Pathogens, Vol 18, Iss 4, p e1010496 (2022)
Attachment to the intestinal epithelium is critical to the lifestyle of the ubiquitous parasite Giardia lamblia. The ventrolateral flange is a sheet-like membrane protrusion at the interface between parasites and attached surfaces. This structure has
Externí odkaz:
https://doaj.org/article/1702a80e08fd48c2aac1b51efbb80ac2
Autor:
Adam K. Glaser, Nicholas P. Reder, Ye Chen, Chengbo Yin, Linpeng Wei, Soyoung Kang, Lindsey A. Barner, Weisi Xie, Erin F. McCarty, Chenyi Mao, Aaron R. Halpern, Caleb R. Stoltzfus, Jonathan S. Daniels, Michael Y. Gerner, Philip R. Nicovich, Joshua C. Vaughan, Lawrence D. True, Jonathan T. C. Liu
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
Light-sheet microscopes are increasingly used for imaging cleared tissues, but have imposed constraints on sample geometries and protocols. Here the authors present a multi-immersion open-top light-sheet microscope to overcome these limitations and e
Externí odkaz:
https://doaj.org/article/90636626e5c14c7aacc695bf6808696a
Autor:
Nicholas A. Pease, Phuc H.B. Nguyen, Marcus A. Woodworth, Kenneth K.H. Ng, Blythe Irwin, Joshua C. Vaughan, Hao Yuan Kueh
Publikováno v:
Cell Reports, Vol 34, Iss 12, Pp 108888- (2021)
Summary: During development, progenitors often differentiate many cell generations after receiving signals. These delays must be robust yet tunable for precise population size control. Polycomb repressive mechanisms, involving histone H3 lysine-27 tr
Externí odkaz:
https://doaj.org/article/7373c09769d246d48eff135d9a67e496
Publikováno v:
The Journal of Physical Chemistry B. 127:2701-2707
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb2413301615e16193fa6348dd439e6a
https://doi.org/10.1021/acs.jpcb.2c09053
https://doi.org/10.1021/acs.jpcb.2c09053
Autor:
Nan Jiang, Jeffrey P Rasmussen, Joshua A Clanton, Marci F Rosenberg, Kory P Luedke, Mark R Cronan, Edward D Parker, Hyeon-Jin Kim, Joshua C Vaughan, Alvaro Sagasti, Jay Z Parrish
Publikováno v:
eLife, Vol 8 (2019)
Interactions between epithelial cells and neurons influence a range of sensory modalities including taste, touch, and smell. Vertebrate and invertebrate epidermal cells ensheath peripheral arbors of somatosensory neurons, including nociceptors, yet t
Externí odkaz:
https://doaj.org/article/b7d9fc63257949cb847bf97bd78c6b4d
Autor:
Jonathan T.C. Liu, Lawrence D. True, Anant Madabhushi, Adam K. Glaser, Andrew Janowczyk, Joshua C. Vaughan, C. Dirk Keene, Jonathan L. Wright, Pingfu Fu, Lindsey A. Barner, Kevin W. Bishop, Qinghua Han, Gan Gao, Robert Serafin, Soyoung Kang, Nadia Postupna, Chenyi Mao, Hongyi Huang, Sarah Hawley, Patrick Leo, Can Koyuncu, Nicholas P. Reder, Weisi Xie
Supplementary methods, notes, figures, tables, video captions, and references
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d7f16227e1ff6b73b748733d8019fce
https://doi.org/10.1158/0008-5472.22593115
https://doi.org/10.1158/0008-5472.22593115
Autor:
Min Yen Lee, Chenyi Mao, Adam K. Glaser, Marcus A. Woodworth, Aaron R. Halpern, Adilijiang Ali, Jonathan T. C. Liu, Joshua C. Vaughan
Publikováno v:
Nature Protocols. 17:819-846
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ef12e9a52dbac041dbef5a1b8092a8d
https://doi.org/10.1038/s41596-021-00667-2
https://doi.org/10.1038/s41596-021-00667-2
Autor:
Jonathan T.C. Liu, Lawrence D. True, Anant Madabhushi, Adam K. Glaser, Andrew Janowczyk, Joshua C. Vaughan, C. Dirk Keene, Jonathan L. Wright, Pingfu Fu, Lindsey A. Barner, Kevin W. Bishop, Qinghua Han, Gan Gao, Robert Serafin, Soyoung Kang, Nadia Postupna, Chenyi Mao, Hongyi Huang, Sarah Hawley, Patrick Leo, Can Koyuncu, Nicholas P. Reder, Weisi Xie
Prostate cancer treatment planning is largely dependent upon examination of core-needle biopsies. The microscopic architecture of the prostate glands forms the basis for prognostic grading by pathologists. Interpretation of these convoluted three-dim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cae9a19c954d4ff0c097ef5aec40f8a
https://doi.org/10.1158/0008-5472.c.6513760.v1
https://doi.org/10.1158/0008-5472.c.6513760.v1