Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Joshua, Rhein"'
Autor:
Mark Okwir, Abigail Link, Bosco Opio, Fred Okello, Ritah Nakato, Betty Nabongo, Jimmy Alal, Joshua Rhein, David Meya, Yu Liu, Paul R. Bohjanen
Publikováno v:
PLoS ONE, Vol 19, Iss 5 (2024)
Externí odkaz:
https://doaj.org/article/284e25f446c74eaa8e34659bdb38c4ea
Autor:
Samuel Okurut, David R. Boulware, Elizabeth Okafor, Joshua Rhein, Henry Kajumbula, Bernard S. Bagaya, Freddie Bwanga, Joseph O. Olobo, Yukari C. Manabe, David B. Meya, Edward N. Janoff
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionSurvival among people with HIV-associated cryptococcal meningitis (CM) remains low, particularly among women, despite the currently optimal use of antifungal drugs. Cryptococcus dissemination into the central nervous system [brain, spinal
Externí odkaz:
https://doaj.org/article/85c7253969b7452594bd58c0ae40b479
Autor:
Frank Mulindwa, Barbara Castelnuovo, Nele Brusselaers, Robert Bollinger, Joshua Rhein, Mutebi Edrisa, Allan Buzibye, Willington Amutuhaire, George Yendewa, Sarah Nabaggala, Eva Laker Agnes Odongpiny, Ronald Kiguba, Aisha Nakawooza, Simon Dujanga, Martin Nabwana, Jean-Marc Schwarz
Publikováno v:
AIDS Research and Therapy, Vol 20, Iss 1, Pp 1-11 (2023)
Abstract Background Following reports of anti-retroviral therapy (ART) experienced Ugandan people living with HIV (PLHIV) presenting with diabetic ketoacidosis weeks to months following a switch to dolutegravir (DTG), the Uganda Ministry of Health re
Externí odkaz:
https://doaj.org/article/58234e13d0684a1e866b4bc5050096d7
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
In the setting of viral challenge, natural killer (NK) cells play an important role as an early immune responder against infection. During this response, significant changes in the NK cell population occur, particularly in terms of their frequency, l
Externí odkaz:
https://doaj.org/article/72bbcef9ff784117bae901b524ae948a
Autor:
Noemia S. Lima, Maryam Musayev, Timothy S. Johnston, Danielle A. Wagner, Amy R. Henry, Lingshu Wang, Eun Sung Yang, Yi Zhang, Kevina Birungi, Walker P. Black, Sijy O’Dell, Stephen D. Schmidt, Damee Moon, Cynthia G. Lorang, Bingchun Zhao, Man Chen, Kristin L. Boswell, Jesmine Roberts-Torres, Rachel L. Davis, Lowrey Peyton, Sandeep R. Narpala, Sarah O’Connell, Leonid Serebryannyy, Jennifer Wang, Alexander Schrager, Chloe Adrienna Talana, Geoffrey Shimberg, Kwanyee Leung, Wei Shi, Rawan Khashab, Asaf Biber, Tal Zilberman, Joshua Rhein, Sara Vetter, Afeefa Ahmed, Laura Novik, Alicia Widge, Ingelise Gordon, Mercy Guech, I-Ting Teng, Emily Phung, Tracy J. Ruckwardt, Amarendra Pegu, John Misasi, Nicole A. Doria-Rose, Martin Gaudinski, Richard A. Koup, Peter D. Kwong, Adrian B. McDermott, Sharon Amit, Timothy W. Schacker, Itzchak Levy, John R. Mascola, Nancy J. Sullivan, Chaim A. Schramm, Daniel C. Douek
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Vaccines against the WA1 SARS-CoV2 strain confer protection against other variants. However, the mechanisms underlying cross-protection are not fully understood. Here, the authors develop a method for rapid analysis of single B cells from patient sam
Externí odkaz:
https://doaj.org/article/b6d4d09b5933465b8ae8f4b440a22b6a
Autor:
Caleb P. Skipper, Katherine Huppler Hullsiek, Fiona V. Cresswell, Kiiza K. Tadeo, Michael Okirwoth, Mark Blackstad, Nelmary Hernandez-Alvarado, Claudia Fernández-Alarcón, Stewart Walukaga, Emily Martyn, Jayne Ellis, Kenneth Ssebambulidde, Lillian Tugume, Edwin Nuwagira, Joshua Rhein, David B. Meya, David R. Boulware, Mark R. Schleiss
Publikováno v:
International Journal of Infectious Diseases, Vol 122, Iss , Pp 785-792 (2022)
Objectives: CMV viremia is associated with increased mortality in persons with HIV. We previously demonstrated that CMV viremia was a risk factor for 10-week mortality in antiretroviral therapy (ART)-naïve persons with cryptococcal meningitis. We in
Externí odkaz:
https://doaj.org/article/b0a922ef9fe944e9a2f7fe858d771042
Autor:
Jonathan Mayito, David B Meya, Akia Miriam, Flavia Dhikusooka, Joshua Rhein, Christine Sekaggya-Wiltshire
Publikováno v:
PLoS ONE, Vol 18, Iss 11, p e0291834 (2023)
BackgroundInterferon-gamma release assay and tuberculin skin test use is limited by costly sundries and cross-reactivity with non-tuberculous mycobacteria and Bacille Calmette-Guérin (BCG) vaccination respectively. We investigated the Monocyte to Ly
Externí odkaz:
https://doaj.org/article/ce376a61089f48e690be6d6679c627cd
Autor:
Kathryn A. Pape, Thamotharampillai Dileepan, William E. Matchett, Charles Ellwood, Samuel Stresemann, Amanda J. Kabage, Daria Kozysa, Clayton Evert, Michael Matson, Sharon Lopez, Peter D. Krueger, Carolyn T. Graiziger, Byron P. Vaughn, Eugenia Shmidt, Joshua Rhein, Timothy W. Schacker, Tyler D. Bold, Ryan A. Langlois, Alexander Khoruts, Marc K. Jenkins
Publikováno v:
JCI Insight, Vol 7, Iss 12 (2022)
Immunosuppressed patients with inflammatory bowel disease (IBD) generate lower amounts of SARS-CoV-2 spike antibodies after mRNA vaccination than healthy controls. We assessed SARS-CoV-2 spike S1 receptor binding domain–specific (S1-RBD–specific)
Externí odkaz:
https://doaj.org/article/eb08f1691f214363a7c22e6224ae5433
Autor:
Caleb P Skipper, Katherine Huppler Hullsiek, Anna Stadelman, Darlisha A Williams, Kenneth Ssebambulidde, Elizabeth Okafor, Lillian Tugume, Edwin Nuwagira, Andrew Akampurira, Abdu K Musubire, Mahsa Abassi, Conrad Muzoora, Joshua Rhein, David R Boulware, David B Meya
Publikováno v:
Journal of Fungi, Vol 9, Iss 1, p 46 (2022)
Cryptococcus is the leading cause of AIDS-related meningitis in sub-Saharan Africa. The clinical implications of a sterile cerebrospinal fluid (CSF) culture among individuals diagnosed with cryptococcal meningitis using CSF cryptococcal antigen (CrAg
Externí odkaz:
https://doaj.org/article/60540634be1549199487c0da73afa219
Autor:
Richard Kwizera, Alisat Sadiq, Jane Frances Ndyetukira, Elizabeth Nalintya, Darlisha Williams, Joshua Rhein, David R. Boulware, David B. Meya, on behalf of the COAT and ASTRO trial teams
Publikováno v:
Research Involvement and Engagement, Vol 6, Iss 1, Pp 1-7 (2020)
Abstract Background Clinical trials remain the cornerstone of improving outcomes for HIV-infected individuals with cryptococcal meningitis. Community engagement aims at involving participants and their advocates as partners in research rather than me
Externí odkaz:
https://doaj.org/article/1516e701b9d84a10b72d87098b777d24