Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Joshua, Montroy"'
Autor:
Donald J. Bastin, Joshua Montroy, Michael A. Kennedy, Andre B. Martel, Risa Shorr, Maryam Ghiasi, Dominique M. Boucher, Boaz Wong, Louise Gresham, Jean-Simon Diallo, Dean A. Fergusson, Manoj M. Lalu, Natasha Kekre, Rebecca C. Auer
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract We conducted a systematic review and meta-analysis of randomized control trials to formally assess the safety and efficacy of autologous whole cell vaccines as immunotherapies for solid tumors. Our primary safety outcome was number, and grad
Externí odkaz:
https://doaj.org/article/ddd371329bd54c08b78dd40a6df911c2
Autor:
Manoj M. Lalu, Natasha Kekre, Joshua Montroy, Maryam Ghiasi, Kevin Hay, Scott McComb, Risini Weeratna, Harold Atkins, Brian Hutton, Ayel Yahya, Ashish Masurekar, Mohamad Sobh, Dean A. Fergusson
Publikováno v:
Systematic Reviews, Vol 12, Iss 1, Pp 1-7 (2023)
Abstract Background Chimeric antigen receptor T cell therapy (CAR-T) represents a promising and exciting new therapy for hematologic malignancies, where prognosis for relapsed/refractory patients remains poor. Encouraging results from clinical trials
Externí odkaz:
https://doaj.org/article/e178a854e819485ba2fe09dae90e30a0
Autor:
Victoria T Hunniford, Agnes Grudniewicz, Dean A Fergusson, Joshua Montroy, Emma Grigor, Casey Lansdell, Manoj M Lalu, On behalf of The Canadian Critical Care Translational Biology Group
Publikováno v:
eLife, Vol 12 (2023)
Background: Multicentric approaches are widely used in clinical trials to assess the generalizability of findings, however, they are novel in laboratory-based experimentation. It is unclear how multilaboratory studies may differ in conduct and result
Externí odkaz:
https://doaj.org/article/c3bacf29ec004c61ba79555030c592f1
Autor:
Manoj M Lalu, Justin Presseau, Madison K Foster, Victoria T Hunniford, Kelly D Cobey, Jamie C Brehaut, Carolina Ilkow, Joshua Montroy, Analyssa Cardenas, Ayni Sharif, Matthew S Jeffers, Dean A Fergusson
Publikováno v:
PLoS Biology, Vol 21, Iss 1, p e3001932 (2023)
Use of rigorous study design methods and transparent reporting in publications are 2 key strategies proposed to improve the reproducibility of preclinical research. Despite promotion of these practices by funders and journals, assessments suggest upt
Externí odkaz:
https://doaj.org/article/7c1b9dca302b43ebafa4f4159c7a047f
Autor:
Gisell Castillo, Manoj Lalu, Sarah Asad, Madison Foster, Natasha Kekre, Dean Fergusson, Terry Hawrysh, Harold Atkins, Kednapa Thavorn, Joshua Montroy, Stuart Schwartz, Robert Holt, Raewyn Broady, Justin Presseau, on behalf of the GO CART team
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-13 (2021)
Abstract Background Novel therapies often fail to reach the bedside due to low trial recruitment rates. Prior to conducting one of the first chimeric antigen receptor (CAR) T cell therapy trials in Canada, we used the Theoretical Domains Framework, a
Externí odkaz:
https://doaj.org/article/430aa40df7a447f89b64632aa30c865a
Autor:
David Moher, Agnes Grudniewicz, Kelly D Cobey, Manoj M Lalu, Joshua Montroy, Gregory L Bryson, Christian Lehmann, Olivier Brandts-Longtin, Euan A Adie, Marc A Albert, Elham Almoli, Faris Almoli, Christophe Dony, Daniel Dunleavy, Rémy Lhoest, Mallory Pitts, Alicia Ricketts, Paul Thirion
Publikováno v:
BMJ Open, Vol 12, Iss 4 (2022)
Introduction Many predatory journals fail to follow best publication practices. Studies assessing the impact of predatory journals have focused on how these articles are cited in reputable academic journals. However, it is possible that research from
Externí odkaz:
https://doaj.org/article/ddee563746c242cd966798b5d0b7ede1
Autor:
Joshua Montroy, Rania Berjawi, Manoj M. Lalu, Eyal Podolsky, Cayden Peixoto, Levent Sahin, Alain Stintzi, David Mack, Dean A. Fergusson
Publikováno v:
BMC Gastroenterology, Vol 20, Iss 1, Pp 1-14 (2020)
Abstract Background Inflammatory bowel disease (IBD) is a debilitating chronic disease with limited treatment options. Resistant starches may represent a novel treatment for IBD. However, its efficacy and safety remain unclear. Our objective was to p
Externí odkaz:
https://doaj.org/article/8dc6b58a940649e7acf731147016481e
Autor:
Madison Foster, Dean A Fergusson, Terry Hawrysh, Justin Presseau, Natasha Kekre, Stuart Schwartz, Gisell Castillo, Sarah Asad, Grace Fox, Harold Atkins, Kednapa Thavorn, Joshua Montroy, Robert A Holt, Zarah Monfaredi, Manoj M Lalu
Publikováno v:
Research Involvement and Engagement, Vol 6, Iss 1, Pp 1-10 (2020)
Abstract Aim Though patient engagement in clinical research is growing, recent reports suggest few clinical trials report on such activities. To address this gap, we describe our approach to patient engagement in the development of a clinical trial p
Externí odkaz:
https://doaj.org/article/41291d56e02947a0aa68b46ceb1c3cfe
Autor:
Alvin Tieu, Kevin Hu, Catherine Gnyra, Joshua Montroy, Dean A. Fergusson, David S. Allan, Duncan J. Stewart, Bernard Thébaud, Manoj M. Lalu
Publikováno v:
Journal of Extracellular Vesicles, Vol 10, Iss 12, Pp n/a-n/a (2021)
Abstract Preclinical studies suggest mesenchymal stromal cell extracellular vesicles (MSC‐EVs) reduce inflammation and improve organ function in lung diseases; however, an objective analysis of all available data is needed prior to translation. Usi
Externí odkaz:
https://doaj.org/article/1135f3706c91491abd39cc98cf17aef2
Autor:
Grace Fox, Dean A. Fergusson, Zeinab Daham, Mark Youssef, Madison Foster, Evelyn Poole, Ayni Sharif, Dawn P. Richards, Kathryn Hendrick, Asher A. Mendelson, Kimberly F. Macala, Zarah Monfaredi, Joshua Montroy, Kirsten M. Fiest, Justin Presseau, Manoj M. Lalu
Publikováno v:
EBioMedicine, Vol 70, Iss , Pp 103484- (2021)
Background: ‘Patient engagement’ involves meaningful collaboration between researchers and ‘patient partners’ to co-create research. It helps ensure that research being conducted is relevant to its ultimate end-users. Although patient engagem
Externí odkaz:
https://doaj.org/article/adb7d3a7384c4ba58fee46815e04a397