Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Joshua, Mell"'
Autor:
Timothy Nacarelli, Ashley Azar, Manali Potnis, Gregg Johannes, Joshua Mell, F. Brad Johnson, Holly Brown-Borg, Eishi Noguchi, Christian Sell
Publikováno v:
Molecular biology of the cell. 33(5)
Cellular senescence is a terminal cell fate characterized by growth arrest and a metabolically active state characterized by high glycolytic activity. Human fibroblasts were placed in a unique metabolic state using a combination of methionine restric
Autor:
Will Dampier, Michael R Nonnemacher, Joshua Mell, Joshua Earl, Garth D Ehrlich, Vanessa Pirrone, Benjamas Aiamkitsumrit, Wen Zhong, Katherine Kercher, Shendra Passic, Jean W Williams, Jeffrey M Jacobson, Brian Wigdahl
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0155382 (2016)
As a result of antiretroviral therapeutic strategies, human immunodeficiency virus type 1 (HIV-1) infection has become a long-term clinically manageable chronic disease for many infected individuals. However, despite this progress in therapeutic cont
Externí odkaz:
https://doaj.org/article/f1cbeb5f8290481ba14b7d940356ffd3
Publikováno v:
EBioMedicine, Vol 1, Iss 2, Pp 99-100 (2014)
Externí odkaz:
https://doaj.org/article/6da2f11bdc084bfe8380320bc548dd4d
Publikováno v:
Annals of the New York Academy of Sciences. 1418(1)
Both methionine restriction and rapamycin treatment are robust longevity-enhancing regimens for which the mechanisms remain unclear. Cellular senescence is a major contributor to the aging process, and we find that both the methionine and rapamycin r