Zobrazeno 1 - 10
of 5 559
pro vyhledávání: '"Joshua, I"'
Autor:
Maltsev, Anna V., Barlas, Yasir Z., Hazan, Adina, Zhang, Rui, Ottolia, Michela, Goldhaber, Joshua I.
Biological systems, particularly the brain, are frequently analyzed as networks, conveying mechanistic insights into their function and pathophysiology. This is the first study of a functional network of cardiac tissue. We use calcium imaging to obta
Externí odkaz:
http://arxiv.org/abs/2405.15841
An important problem in time-series analysis is modeling systems with time-varying dynamics. Probabilistic models with joint continuous and discrete latent states offer interpretable, efficient, and experimentally useful descriptions of such data. Co
Externí odkaz:
http://arxiv.org/abs/2306.03291
Autor:
Joshua I Miller, Kathryn L Hassell, Yvonne Kellar-Guenther, Stacey Quesada, Rhonda West, Marci Sontag
Publikováno v:
JMIR Public Health and Surveillance, Vol 10, Pp e64995-e64995 (2024)
Abstract BackgroundSickle cell disease (SCD) is a genetic blood disorder that affects approximately 100,000 individuals in the United States, with the highest prevalence among Black or African American populations. While advances in care have improv
Externí odkaz:
https://doaj.org/article/1dccaa433c474925ac5951ed6bfe7610
Autor:
Kyle Scranton, Scott John, Marina Angelini, Federica Steccanella, Soban Umar, Rui Zhang, Joshua I. Goldhaber, Riccardo Olcese, Michela Ottolia
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The Na+-Ca2+ exchanger (NCX1) is the dominant Ca2+ extrusion mechanism in cardiac myocytes. NCX1 activity is inhibited by intracellular Na+ via a process known as Na+-dependent inactivation. A central question is whether this inactivation pl
Externí odkaz:
https://doaj.org/article/7d9d07a07d3147cf8e90bdb931f0b845
Autor:
de Leon, Jerome P., Livingston, John H., Jenkins, James S., Vines, Jose I., Wittenmyer, Robert A., Clark, Jake T., Winn, Joshua I. M., Addison, Brett, Ballard, Sarah, Bayliss, Daniel, Beichman, Charles, Benneke, Björn, Berardo, David Anthony, Bowler, Brendan P., Brown, Tim, Bryant, Edward M., Christiansen, Jessie, Ciardi, David, Collins, Karen A., Collins, Kevin I., Crossfield, Ian, Deming, Drake, Dragomir, Diana, Dressing, Courtney D., Fukui, Akihiko, Gan, Tianjun, Giacalone, Steven, Gill, Samuel, Alvarez, Erica Gonz\' alez, Hesse, Katharine, Horner, Jonathan, Howell, Steve B., Jenkins, Jon M., Kane, Stephen R., Kendall, Alicia, Kielkopf, John F., Kreidberg, Laura, Latham, David W., Liu, Huigen, Lund, Michael B., Matson, Rachel, Matthews, Elisabeth, Mengel, Matthew W., Morales, Farisa, Mori, Mayuko, Narita, Norio, Nishiumi, Taku, Okumura, Jack, Plavchan, Peter, Quinn, Sam, Rabus, Markus, Ricker, George, Rudat, Alexander, Schlieder, Joshua, Schwarz, Richard P., Seager, Sara, Shporer, Avi, Smith, Alexis M. S., Sphorer, Avi, Stassun, Keivan, Tamura, Motohide, Tan, Thiam Guan, Tinney, C. G., Vanderspek, Roland, Gorjian, Varoujan, Werner, Michael W., West, Richard G., Wright, Duncan, Zhang, Hui, Zhou, George
Transiting exoplanets orbiting young nearby stars are ideal laboratories for testing theories of planet formation and evolution. However, to date only a handful of stars with age <1 Gyr have been found to host transiting exoplanets. Here we present t
Externí odkaz:
http://arxiv.org/abs/2210.08179